Literature DB >> 19746808

Quantitative megavoltage radiation therapy dosimetry using the storage phosphor KCl: Eu2+.

Zhaohui Han1, Joseph P Driewer, Yuanshui Zheng, Daniel A Low, H Harold Li.   

Abstract

This work, for the first time, reports the use of europium doped potassium chloride (KCl:Eu2+) storage phosphor for quantitative megavoltage radiation therapy dosimetry. In principle, KCl:Eu2+ functions using the same photostimulatated luminescence (PSL) mechanism as commercially available BaFBr0.85I0.15:Eu2+ material that is used for computed radiography (CR) but features a significantly smaller effective atomic number--18 versus 49--making it a potentially useful material for nearly tissue-equivalent radiation dosimetry. Cylindrical KCl:Eu2+ dosimeters, 7 mm in diameter and 1 mm thick, were fabricated in-house. Dosimetric properties, including radiation hardness, response linearity, signal fading, dose rate sensitivity, and energy dependence, were studied with a laboratory optical reader after irradiation by a linear accelerator. The overall experimental uncertainty was estimated to be within +/-2.5%. The findings were (1) KCl:Eu2+ showed satisfactory radiation hardness. There was no significant change in the stimulation spectra after irradiation up to 200 Gy when compared to a fresh dosimeter, indicating that this material could be reused at least 100 times if 2 Gy per use was assumed, e.g., for patient-specific IMRT QA. (2) KCl:Eu2+ exhibited supralinear response to dose after irradiation from 0 to 800 cGy. (3) After x ray irradiation, the PSL signal faded with time and eventually reached a fading rate of about 0.1 % /h after 12 h. (4) The sensitivity of the dosimeter was independent of the dose rate ranging from 15 to 1000 cGy/min. (5) The sensitivity showed no beam energy dependence for either open x ray or megavoltage electron fields. (6) Over-response to low-energy scattered photons was comparable to radiographic film, e.g., Kodak EDR2 film. By sandwiching dosimeters between low-energy photon filters (0.3 mm thick lead foils) during irradiation, the over-response was reduced. The authors have demonstrated that KCl:Eu2+ dosimeters have many desirable dosimetric characteristics that make the material conducive to radiation therapy dosimetry. In the future, a large-area KCl:Eu2+-based CR plate with a thickness of the order of a few microns, created using modern thin film techniques, could provide a reusable, quantitative, high-resolution two-dimensional dosimeter with minimal energy dependence.

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Year:  2009        PMID: 19746808      PMCID: PMC2724175          DOI: 10.1118/1.3171687

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  28 in total

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  10 in total

1.  Theoretical and empirical investigations of KCl : Eu2+ for nearly water-equivalent radiotherapy dosimetry.

Authors:  Yuanshui Zheng; Zhaohui Han; Joseph P Driewer; Daniel A Low; H Harold Li
Journal:  Med Phys       Date:  2010-01       Impact factor: 4.071

2.  Evaluation of the absorbed dose to the breast using radiochromic film in a dedicated CT mammotomography system employing a quasi-monochromatic x-ray beam.

Authors:  Dominic J Crotty; Samuel L Brady; D'Vone C Jackson; Greta I Toncheva; Colin E Anderson; Terry T Yoshizumi; Martin P Tornai
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3.  Radiation hardness of the storage phosphor europium doped potassium chloride for radiation therapy dosimetry.

Authors:  Joseph P Driewer; Haijian Chen; Andres Osvet; Daniel A Low; H Harold Li
Journal:  Med Phys       Date:  2011-08       Impact factor: 4.071

4.  The role of activator concentration and precipitate formation on optical and dosimetric properties of KCl:Eu(2+) storage phosphor detectors.

Authors:  Rachael A Hansel; Zhiyan Xiao; Yanle Hu; Olga Green; Deshan Yang; H Harold Li
Journal:  Med Phys       Date:  2013-09       Impact factor: 4.071

5.  Temporal signal stability of KCl:Eu(2+) storage phosphor dosimeters.

Authors:  Zhiyan Xiao; Rachael Hansel; Haijian Chen; Dongsu Du; Deshan Yang; H Harold Li
Journal:  Med Phys       Date:  2013-02       Impact factor: 4.071

6.  X ray storage performance of KCl:Eu2+ with high cumulated dose.

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7.  Temperature dependence of the photostimulated luminescence in KCl:Eu2+

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8.  Two-dimensional high spatial-resolution dosimeter using europium doped potassium chloride: a feasibility study.

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9.  Performance of KCl:Eu2+ storage phosphor dosimeters for low-dose measurements.

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  10 in total

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