Literature DB >> 20175476

Theoretical and empirical investigations of KCl : Eu2+ for nearly water-equivalent radiotherapy dosimetry.

Yuanshui Zheng1, Zhaohui Han, Joseph P Driewer, Daniel A Low, H Harold Li.   

Abstract

PURPOSE: The low effective atomic number, reusability, and other computed radiography-related advantages make europium doped potassium chloride (KCl : Eu2+) a promising dosimetry material. The purpose of this study is to model KCl : Eu2+ point dosimeters with a Monte Carlo (MC) method and, using this model, to investigate the dose responses of two-dimensional (2D) KCl : Eu2+ storage phosphor films (SPFs).
METHODS: KCl : Eu2+ point dosimeters were irradiated using a 6 MV beam at four depths (5-20 cm) for each of five square field sizes (5 x 5-25 x 25 cm2). The dose measured by KCl : Eu2+ was compared to that measured by an ionization chamber to obtain the magnitude of energy dependent dose measurement artifact. The measurements were simulated using DOSXYZnrc with phase space files generated by BEAMnrcMP. Simulations were also performed for KCl : Eu2+ films with thicknesses ranging from 1 microm to 1 mm. The work function of the prototype KCl : Eu2+ material was determined by comparing the sensitivity of a 150 microm thick KCl : Eu2+ film to a commercial BaFBr0.85 I0.15 : Eu(2+)-based SPF with a known work function. The work function was then used to estimate the sensitivity of a 1 microm thick KCl : Eu2+ film.
RESULTS: The simulated dose responses of prototype KCl : Eu2+ point dosimeters agree well with measurement data acquired by irradiating the dosimeters in the 6 MV beam with varying field size and depth. Furthermore, simulations with films demonstrate that an ultrathin KCl : Eu2+ film with thickness of the order of 1 microm would have nearly water-equivalent dose response. The simulation results can be understood using classic cavity theories. Finally, preliminary experiments and theoretical calculations show that ultrathin KCl : Eu2+ film could provide excellent signal in a 1 cGy dose-to-water irradiation.
CONCLUSIONS: In conclusion, the authors demonstrate that KCl : Eu(2+)-based dosimeters can be accurately modeled by a MC method and that 2D KCl : Eu2+ films of the order of 1 microm thick would have minimal energy dependence. The data support the future research and development of a KCl : Eu2+ storage phosphor-based system for quantitative, high-resolution multidimensional radiation therapy dosimetry.

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Year:  2010        PMID: 20175476      PMCID: PMC2801734          DOI: 10.1118/1.3271338

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  20 in total

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9.  Quantitative megavoltage radiation therapy dosimetry using the storage phosphor KCl: Eu2+.

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2.  Radiation hardness of the storage phosphor europium doped potassium chloride for radiation therapy dosimetry.

Authors:  Joseph P Driewer; Haijian Chen; Andres Osvet; Daniel A Low; H Harold Li
Journal:  Med Phys       Date:  2011-08       Impact factor: 4.071

3.  The role of activator concentration and precipitate formation on optical and dosimetric properties of KCl:Eu(2+) storage phosphor detectors.

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7.  Two-dimensional high spatial-resolution dosimeter using europium doped potassium chloride: a feasibility study.

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