| Literature DB >> 35270497 |
Jung-Ah Kwon1, Yoon-Kyum Shin2,3, Deok-Ju Kim4, Sung-Rae Cho2,3,5,6.
Abstract
Therapeutic goals for hemiplegic patients with neurological impairments are mainly focused on improving their independent lives. Based on the previously reported effectiveness of Wii Fit balance training, this study investigated the most influential outcomes after long-term intensive training (including balance and functional factors) on quality of life in hemiplegic patients. The intervention group (n = 21) received Nintendo Wii Fit balance training under supervision, and control group (n = 20) received conventional balance training by an occupational therapist. Two groups were matched based on age and onset duration. Both groups received a total of 15 treatments for 30 min per session, twice a week for 8 weeks. There were significant improvements not only in balance confidence and activities of daily living, but also in body composition, such as fat proportion and metabolic rate, in the intervention group compared to the control group (p < 0.05). In particular, balance confidence significantly affected EuroQoL Visual Analogue Scale according to stepwise multiple regression analyses in this study. These results demonstrated that Wii Fit balance training using virtual reality improved the quality of life of hemiplegic patients while overcoming the asymmetrical weight distribution of the affected side via the self-modulating biofeedback exercises.Entities:
Keywords: Wii Fit balance training; balance confidence; health-related quality of life; hemiplegic patients
Mesh:
Year: 2022 PMID: 35270497 PMCID: PMC8910515 DOI: 10.3390/ijerph19052805
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Clinical characteristics of subjects (N = 41).
| Intervention Group (n = 21) | Control Group (n = 20) |
| |
|---|---|---|---|
| Age, years | 46.52 ± 14.15 † | 47.00 ± 13.82 | 0.252 |
| Gender, n(%) | 0.087 | ||
| Male | 7 (33.3) | 12 (60.0) | |
| Female | 14 (66.7) | 8 (40.0) | |
| Diagnosis, n (%) | 0.511 | ||
| Stroke | 15 (71.4) | 14 (70.0) | |
| Traumatic brain injury | 2 (9.5) | 4 (20.0) | |
| Tumor | 4 (19.1) | 2 (10.0) | |
| Onset duration, years | 9.16 ± 7.92 | 6.11 ± 4.60 | 0.452 |
| Affected side, n (%) | 0.867 | ||
| Rt. side | 11 (52.3) | 11 (55.0) | |
| Lt. side | 10 (47.7) | 9 (45.0) |
† Mean ± SD; continuous variables analyzed by independent t-test; categorical variables analyzed by Chi-square test.
Figure 1Procedures of the study.
Changes in the symmetricity of weight distribution and balance age.
| Variables (Unit) Group | Pre | Post |
| Difference |
|
|---|---|---|---|---|---|
| Affected side (%) | |||||
| Intervention | 44.83 ± 7.25 † | 50.25 ± 4.36 | 0.001 ** | 5.31 ± 1.33 § | 0.004 ** |
| Control | 51.26 ± 7.67 | 50.05 ± 5.24 | 0.492 | −1.21 ± 1.72 | |
| Less affected side (%) | |||||
| Intervention | 55.17 ± 7.25 | 49.75 ± 4.36 | 0.001 ** | −5.42 ± 1.33 | 0.004 ** |
| Control | 48.75 ± 7.67 | 49.95 ± 5.24 | 0.492 | 1.21 ± 1.72 | |
| Balance age (years) | |||||
| Intervention | 59.14 ± 12.95 | 49.43 ± 11.50 | 0.000 *** | −9.71 ± 1.32 | 0.003 ** |
| Control | 58.20 ± 15.04 | 55.15 ± 16.17 | 0.108 | −2.90 ± 1.75 |
† Mean ± SD; § Mean ± SE; ** p < 0.01 *** p < 0.001; p a, paired t-test; p b, independent t-test.
Figure 2Representative outcomes showing significant group differences in this study. Values are mean ± SE; ** p < 0.01, *** p < 0.001; Dotted line: the expected value indicating an average of all variables from individuals in each outcome measure; WBB (AS/LS): weight distribution using Wii Balance Board in the affected side or the less affected side; BBS: Berg Balance Scale; ABC: Activities-specific Balance Confidence scale; FIM: Functional Independence Measure; EQ-5D-5L: EuroQoL 5 Dimensions (Total score).
Changes in balance and functional outcomes.
| Variables (Unit) Group | Pre | Post |
| Difference |
| |
|---|---|---|---|---|---|---|
| BBS (score) | ||||||
| Intervention | 42.10 ± 9.36 † | 48.10 ± 7.18 | 0.000 *** | 5.90 ± 0.69 § | 0.000 *** | |
| Control | 47.00 ± 8.52 | 48.35 ± 7.71 | 0.001** | 1.30 ± 0.33 | ||
| ABC (score) | ||||||
| Intervention | 55.95 ± 22.74 | 69.76 ± 20.98 | 0.000 *** | 14.19 ± 1.82 | 0.000 *** | |
| Control | 64.99 ± 29.82 | 66.10 ± 27.87 | 0.501 | 1.16 ± 1.64 | ||
| FIM (score) | ||||||
| Intervention | 30.14 ± 2.35 | 31.67 ± 2.80 | 0.000 *** | 1.52 ± 0.26 | 0.000 *** | |
| Control | 30.90 ± 3.34 | 31.15 ± 3.01 | 0.096 | 0.25 ± 0.14 | ||
| Walking speed (m/s) | Regular speed | |||||
| Intervention | 1.54 ± 0.50 | 1.29 ± 0.41 | 0.000 *** | −0.22 ± 0.05 | 0.091 | |
| Control | 1.30 ± 0.51 | 1.25 ± 0.54 | 0.390 | −0.08 ± 0.07 | ||
| Fast speed | ||||||
| Intervention | 1.21 ± 0.50 | 1.06 ± 0.40 | 0.003 ** | −0.14 ± 0.05 | 0.144 | |
| Control | 1.03 ± 0.38 | 0.96 ± 0.32 | 0.219 | 0.05 ± 0.12 | ||
† Mean ± SD; § Mean ± SE; ** p < 0.01; *** p < 0.001; p a, paired t-test; p b, independent t-test; BBS: Berg Balance Scale; ABC: Activity-specific Balance Confidence scale; FIM: Functional Independence Measure; walking speed in the 10-meter walk test.
Changes in body composition.
| Variable (Unit) Group | Pre | Post |
| Difference |
| |
|---|---|---|---|---|---|---|
| Body composition | BMI (kg/m2) | |||||
| Intervention | 23.32 ± 2.89 † | 23.44 ± 3.29 | 0.666 | 0.12 ± 0.27 § | 0.842 | |
| Control | 24.89 ± 3.39 | 24.83 ± 3.58 | 0.849 | 0.04 ± 0.29 | ||
| Weight (kg) | ||||||
| Intervention | 64.73 ± 11.65 | 64.30 ± 12.41 | 0.473 | −0.42 ± 0.59 | 0.169 | |
| Control | 69.79 ± 14.34 | 70.51 ± 14.95 | 0.213 | 0.72 ± 0.56 | ||
| Body fat rate (%) | ||||||
| Intervention | 33.22 ± 7.60 | 29.98 ± 8.06 | 0.034 * | −3.30 ± 1.41 | 0.109 | |
| Control | 29.99 ± 7.74 | 29.55 ± 7.32 | 0.571 | −0.70 ± 0.71 | ||
| Body fat amount (kg) | ||||||
| Intervention | 21.09 ± 5.39 | 18.40 ± 4.53 | 0.021 * | −2.69 ± 1.08 | 0.021 * | |
| Control | 21.04 ± 6.66 | 21.39 ± 7.11 | 0.600 | 0.35 ± 0.65 | ||
| Muscle mass (kg) | ||||||
| Intervention | 23.37 ± 6.30 | 24.99 ± 8.17 | 0.039 * | 1.61 ± 0.73 | 0.122 | |
| Control | 26.83 ± 6.82 | 27.25 ± 6.76 | 0.133 | 0.37 ± 0.27 | ||
| Basic metabolic rate (%) | ||||||
| Intervention | 1303.29 ± 232.26 | 1374.24 ± 256.43 | 0.017 * | 70.95 ± 27.18 | 0.038 * | |
| Control | 1438.25 ± 268.22 | 1437.50 ± 240.49 | 0.969 | −0.75 ± 18.91 | ||
| Mid-thigh | Affected side (cm) | |||||
| Intervention | 52.64 ± 4.91 † | 54.33 ± 4.41 | 0.027 * | 1.71 ± 0.70 § | 0.658 | |
| Control | 49.95 ± 8.94 | 51.25 ± 9.31 | 0.021 * | 1.33 ± 0.51 | ||
| Less affected side (cm) | ||||||
| Intervention | 54.88 ± 4.34 | 56.48 ± 4.56 | 0.065 | 1.60 ± 0.82 | 0.249 | |
| Control | 52.65 ± 7.82 | 53.18 ± 8.24 | 0.305 | 0.48 ± 0.50 | ||
† Mean ± SD; § Mean ± SE; * p < 0.05; p a, paired t-test; p b, independent t-test; BMI: Body Mass Index.
Changes in quality of life: EQ-5D-5L and EQ-VAS.
| Variables (Unit) Group | Pre | Post |
| Difference |
| |
|---|---|---|---|---|---|---|
| EQ-5D-5L | Mobility (score) | |||||
| Intervention | 2.33 ± 0.91 † | 1.81 ± 0.87 | 0.001 ** | −0.43 ± 0.18 § | 0.051 | |
| Control | 2.20 ± 0.95 | 2.15 ± 0.93 | 0.330 | −0.05 ± 0.05 | ||
| Self-care (score) | ||||||
| Intervention | 1.95 ± 0.80 | 1.95 ± 0.80 | — | — | — | |
| Control | 1.95 ± 0.69 | 1.95 ± 0.69 | — | — | ||
| Activity (score) | ||||||
| Intervention | 2.33 ± 0.73 | 2.33 ± 0.73 | — | — | — | |
| Control | 2.20 ± 0.62 | 2.20 ± 0.62 | — | — | ||
| Pain (score) | ||||||
| Intervention | 2.10 ± 0.70 | 2.10 ± 0.70 | — | — | — | |
| Control | 2.20 ± 0.70 | 2.20 ± 0.70 | — | — | ||
| Anxiety (score) | ||||||
| Intervention | 1.95 ± 0.67 | 1.90 ± 0.62 | 0.329 | −0.05 ± 0.05 | 0.329 | |
| Control | 1.95 ± 0.76 | 1.95 ± 0.76 | — | — | ||
| Total score | ||||||
| Intervention | 10.67 ± 2.33 | 10.10 ± 2.34 | 0.001 ** | −0.57 ± 0.15 | 0.003 ** | |
| Control | 10.50 ± 2.98 | 10.45 ± 2.96 | 0.330 | −0.05 ± 0.05 | ||
| EQ-VAS (score) | Intervention | 76.24 ± 14.07 † | 80.90 ± 10.30 | 0.003 ** | 2.76 ± 1.62 § | 0.592 |
| Control | 75.45 ± 16.89 | 77.30 ± 14.86 | 0.110 | 1.70 ± 1.08 | ||
† Mean ± SD; § Mean ± SE; ** p < 0.01; —, not observed difference between variables; p a, paired t-test; p b, independent t-test; EQ-5D-5L: EuroQoL 5 Dimensions; EQ-VAS: EuroQoL Visual Analogue Scale.
Factors affecting health-related quality of life.
| Variable | Model 1 | Model 2 | ||||||
|---|---|---|---|---|---|---|---|---|
| β |
| Odds Ratio | 95% CI | β |
| Odds Ratio | 95% CI | |
| Gender (female) | 0.105 | 0.479 | 2.651 | −4.878–10.180 | 0.202 | 0.203 | 5.078 | −2.885–13.041 |
| Age | −0.030 | 0.870 | −0.027 | −0.364–0.309 | 0.113 | 0.545 | 0.104 | −0.242–0.449 |
| Diagnosis (tumor) | ||||||||
| Stroke | −0.650 | 0.002 ** | −17.927 | −28.828–−7.026 | −0.448 | 0.021 * | −13.457 | −24.775–−2.139 |
| TBI | −0.431 | 0.046 * | −15.281 | −30.251–−0.310 | −0.377 | 0.074 | −13.382 | −28.150–1.387 |
| Onset duration | −0.217 | 0.150 | −0.417 | −0.991–0.158 | −0.185 | 0.202 | −0.355 | −0.910–0.200 |
| BBS | 0.307 | 0.070 | 0.530 | −0.046–1.107 | ||||
| ABC | 0.411 | 0.017 * | 0.214 | 0.040–0.388 | ||||
| FIM | 0.273 | 0.100 | 1.205 | −0.243–2.652 | ||||
| R2 | 0.279 | 0.396 | ||||||
| Adjusted R2 | 0.176 | 0.245 | ||||||
| F( | 2.771 (0.036 *) | 2.624 (0.025 *) | ||||||
* p < 0.05 ** p < 0.01; TBI: Traumatic Brain Injury; BBS: Berg Balance Scale; ABC: Activity-specific Balance Confidence scale; FIM: Functional Independence Measure; CI: Confidence Interval.