Literature DB >> 27182077

Characterization of Large-Area SiPM Array for PET Applications.

Junwei Du1, Yongfeng Yang1, Xiaowei Bai1, Martin S Judenhofer1, Eric Berg1, Kun Di1, Steve Buckley2, Carl Jackson2, Simon R Cherry1.   

Abstract

The performance of an 8 × 8 array of 6.0 × 6.0 mm2 (active area) SiPMs was evaluated for PET applications using crystal arrays with different pitch sizes (3.4 mm, 1.5 mm, 1.35 mm and 1.2 mm) and custom designed five-channel front-end readout electronics (four channels for position information and one channel for timing information). The total area of this SiPM array is 57.4 × 57.4 mm2, and the pitch size is 7.2 mm. It was fabricated using enhanced blue sensitivity SiPMs (MicroFB-60035-SMT) with peak spectral sensitivity at 420 nm. The performance of the SiPM array was characterized by measuring flood histogram decoding quality, energy resolution, timing resolution and saturation at several bias voltages (from 25.0 V to 30.0 V in 0.5 V intervals) and two different temperatures (5 °C and 20 °C). Results show that the best flood histogram was obtained at a bias voltage of 28.0 V and 5 °C and an array of polished LSO crystals with a pitch as small as 1.2 mm can be resolved. No saturation was observed up to a bias voltage of 29.5 V during the experiments, due to adequate light sharing between SiPMs. Energy resolution and timing resolution at 5 °C ranged from 12.7 ± 0.8% to 14.6 ± 1.4 % and 1.58 ± 0.13 ns to 2.50 ± 0.44 ns, for crystal array pitch sizes of 3.4 mm and 1.2 mm respectively. Superior flood histogram quality, energy resolution and timing resolution were obtained with larger crystal array pitch sizes and at lower temperature. Based on our findings, we conclude that this large-area SiPM array can serve as a suitable photodetector for high-resolution small-animal PET or dedicated human brain PET scanners.

Entities:  

Keywords:  Instrumentation; Nuclear medicine; PET; Silicon photomultiplier

Year:  2016        PMID: 27182077      PMCID: PMC4863987          DOI: 10.1109/TNS.2015.2499726

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  18 in total

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Journal:  J Nucl Med       Date:  2012-03-13       Impact factor: 10.057

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Review 3.  An outlook on future design of hybrid PET/MRI systems.

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Journal:  Med Phys       Date:  2011-10       Impact factor: 4.071

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Authors:  Martin S Judenhofer; Bernd J Pichler; Simon R Cherry
Journal:  Phys Med Biol       Date:  2005-01-07       Impact factor: 3.609

5.  Evaluation of Matrix9 silicon photomultiplier array for small-animal PET.

Authors:  Junwei Du; Jeffrey P Schmall; Yongfeng Yang; Kun Di; Emilie Roncali; Gregory S Mitchell; Steve Buckley; Carl Jackson; Simon R Cherry
Journal:  Med Phys       Date:  2015-02       Impact factor: 4.071

6.  MR compatibility aspects of a silicon photomultiplier-based PET/RF insert with integrated digitisation.

Authors:  Bjoern Weissler; Pierre Gebhardt; Christoph W Lerche; Jakob Wehner; Torsten Solf; Benjamin Goldschmidt; Jane E Mackewn; Paul K Marsden; Fabian Kiessling; Michael Perkuhn; Dirk Heberling; Volkmar Schulz
Journal:  Phys Med Biol       Date:  2014-08-14       Impact factor: 3.609

7.  A sub-millimeter resolution PET detector module using a multi-pixel photon counter array.

Authors:  Tae Yong Song; Heyu Wu; Sergey Komarov; Stefan B Siegel; Yuan-Chuan Tai
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8.  Timing and Energy Resolution of new near-UV SiPMs coupled to LaBr3:Ce for TOF-PET.

Authors:  Jeffrey P Schmall; Rony I Wiener; Suleman Surti; Alessandro Ferri; Alberto Gola; Alessandro Tarolli; Claudio Piemonte; Joel S Karp
Journal:  IEEE Trans Nucl Sci       Date:  2014-10       Impact factor: 1.679

9.  A Simple Capacitive Charge-Division Readout for Position-Sensitive Solid-State Photomultiplier Arrays.

Authors:  Junwei Du; Jeffrey P Schmall; Yongfeng Yang; Kun Di; Purushottam A Dokhale; Kanai S Shah; Simon R Cherry
Journal:  IEEE Trans Nucl Sci       Date:  2013-10       Impact factor: 1.679

10.  A Study of Position-Sensitive Solid-State Photomultiplier Signal Properties.

Authors:  Jeffrey P Schmall; Junwei Du; Martin S Judenhofer; Purushottam Dokhale; James Christian; Mickel McClish; Kanai S Shah; Simon R Cherry
Journal:  IEEE Trans Nucl Sci       Date:  2014-06-12       Impact factor: 1.679

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  12 in total

1.  Small animal, positron emission tomography-magnetic resonance imaging system based on a clinical magnetic resonance imaging scanner: evaluation of basic imaging performance.

Authors:  Raymond R Raylman; Patrick Ledden; Alexander V Stolin; Bob Hou; Ganghadar Jaliparthi; Peter F Martone
Journal:  J Med Imaging (Bellingham)       Date:  2018-09-08

2.  A depth-of-interaction encoding PET detector module with dual-ended readout using large-area silicon photomultiplier arrays.

Authors:  Junwei Du; Xiaowei Bai; Simon R Cherry
Journal:  Phys Med Biol       Date:  2018-12-14       Impact factor: 3.609

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4.  Performance of a high-resolution depth-encoding PET detector module using linearly-graded SiPM arrays.

Authors:  Junwei Du; Xiaowei Bai; Alberto Gola; Fabio Acerbi; Alessandro Ferri; Claudio Piemonte; Yongfeng Yang; Simon R Cherry
Journal:  Phys Med Biol       Date:  2018-02-05       Impact factor: 3.609

5.  A high resolution and high detection efficiency depth-encoding detector for brain positron emission tomography based on a 0.75 mm pitch scintillator array.

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Journal:  J Instrum       Date:  2021-05-20       Impact factor: 1.415

6.  Performance of Dual-Ended Readout PET Detectors Based on BGO Arrays and BaSO4 Reflector.

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7.  Impact of event positioning algorithm on performance of a whole-body PET scanner using one-to-one coupled detectors.

Authors:  S Surti; J S Karp
Journal:  Phys Med Biol       Date:  2018-03-02       Impact factor: 3.609

8.  Shared-photodetector readout to improve the sensitivity of positron emission tomography.

Authors:  Junwei Du; Peng Peng; Xiaowei Bai; Simon R Cherry
Journal:  Phys Med Biol       Date:  2018-10-09       Impact factor: 3.609

9.  Improving Edge Crystal Identification in Flood Histograms Using Triangular Shape Crystals.

Authors:  Peng Peng; Chih-Chieh Liu; Junwei Du; Xiaowei Bai; Simon R Cherry
Journal:  Biomed Phys Eng Express       Date:  2018-02-09

10.  A depth-encoding PET detector for high resolution PET using 1 mm SiPMs.

Authors:  Junwei Du; Xiaowei Bai; Simon R Cherry
Journal:  Phys Med Biol       Date:  2020-08-19       Impact factor: 3.609

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