Literature DB >> 25530626

Timing and Energy Resolution of new near-UV SiPMs coupled to LaBr3:Ce for TOF-PET.

Jeffrey P Schmall1, Rony I Wiener1, Suleman Surti1, Alessandro Ferri2, Alberto Gola2, Alessandro Tarolli2, Claudio Piemonte2, Joel S Karp1.   

Abstract

The high light output and fast decay time of LaBr3:Ce scintillation detectors leads to excellent timing performance. To realize the potential of timing resolution with LaBr3:Ce we have investigated the performance with SiPMs, which enable 1-to-1 coupling to individual crystals, and which have been optimized for the near-ultraviolet (NUV) scintillation light emission of LaBr3:Ce. Coincidence timing resolution (CTR) of 100 ps was measured for a 4×4×5 mm3 LaBr3:30%Ce crystal directly coupled to a large-area 4×4 mm2 NUV-SiPM. Results show very little dependence on temperature, in the range of -20° to 20°C, and bias voltage, from 2 V to 5 V over breakdown. Optimal performance was achieved at an over-voltage (OV) range of 3 V - 5 V, at which high gain and high photon detection efficiency are achieved. Though saturation was evident at 511 keV, an energy resolution of 6.8% was measured after correcting for non-linearity. We also measured a CTR of 110 ps for a 4×4×5mm3 LaBr3:5%Ce crystal and 245 ps for a 4×4×30 mm3 LaBr3:5%Ce crystal using the NUV-SIPM. The poorer timing measurement for the 30-mm long crystal is due mainly to a systematic shift in the time pick-off as a function of the depth-of-interaction. The excellent temperature stability, fast rise time, high gain, and low noise of the NUV-SiPM make it a practical and highly appealing photodetector for the readout of a LaBr3:Ce TOF-PET detector.

Entities:  

Year:  2014        PMID: 25530626      PMCID: PMC4266942          DOI: 10.1109/TNS.2014.2346579

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  13 in total

1.  Benefit of time-of-flight in PET: experimental and clinical results.

Authors:  Joel S Karp; Suleman Surti; Margaret E Daube-Witherspoon; Gerd Muehllehner
Journal:  J Nucl Med       Date:  2008-02-20       Impact factor: 10.057

2.  DOI Determination by Rise Time Discrimination in Single-Ended Readout for TOF PET Imaging.

Authors:  R I Wiener; S Surti; J S Karp
Journal:  IEEE Trans Nucl Sci       Date:  2013-06       Impact factor: 1.679

3.  Performance of FBK high-density SiPM technology coupled to Ce:LYSO and Ce:GAGG for TOF-PET.

Authors:  Alessandro Ferri; Alberto Gola; Nicola Serra; Alessandro Tarolli; Nicola Zorzi; Claudio Piemonte
Journal:  Phys Med Biol       Date:  2014-02-03       Impact factor: 3.609

4.  Time-of-flight positron emission tomography: status relative to conventional PET.

Authors:  T F Budinger
Journal:  J Nucl Med       Date:  1983-01       Impact factor: 10.057

5.  Performance of Philips Gemini TF PET/CT scanner with special consideration for its time-of-flight imaging capabilities.

Authors:  Suleman Surti; Austin Kuhn; Matthew E Werner; Amy E Perkins; Jeffrey Kolthammer; Joel S Karp
Journal:  J Nucl Med       Date:  2007-03       Impact factor: 10.057

6.  Improvement in lesion detection with whole-body oncologic time-of-flight PET.

Authors:  Georges El Fakhri; Suleman Surti; Cathryn M Trott; Joshua Scheuermann; Joel S Karp
Journal:  J Nucl Med       Date:  2011-02-14       Impact factor: 10.057

7.  Physical performance of the new hybrid PET∕CT Discovery-690.

Authors:  V Bettinardi; L Presotto; E Rapisarda; M Picchio; L Gianolli; M C Gilardi
Journal:  Med Phys       Date:  2011-10       Impact factor: 4.071

8.  An assessment of the impact of incorporating time-of-flight information into clinical PET/CT imaging.

Authors:  Cristina Lois; Bjoern W Jakoby; Misty J Long; Karl F Hubner; David W Barker; Michael E Casey; Maurizio Conti; Vladimir Y Panin; Dan J Kadrmas; David W Townsend
Journal:  J Nucl Med       Date:  2010-01-15       Impact factor: 10.057

9.  The imaging performance of a LaBr3-based PET scanner.

Authors:  M E Daube-Witherspoon; S Surti; A Perkins; C C M Kyba; R Wiener; M E Werner; R Kulp; J S Karp
Journal:  Phys Med Biol       Date:  2010-01-07       Impact factor: 3.609

10.  Impact of time-of-flight on PET tumor detection.

Authors:  Dan J Kadrmas; Michael E Casey; Maurizio Conti; Bjoern W Jakoby; Cristina Lois; David W Townsend
Journal:  J Nucl Med       Date:  2009-07-17       Impact factor: 10.057

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  3 in total

1.  Quantitative and Visual Assessments toward Potential Sub-mSv or Ultrafast FDG PET Using High-Sensitivity TOF PET in PET/MRI.

Authors:  Spencer C Behr; Emma Bahroos; Randall A Hawkins; Lorenzo Nardo; Vahid Ravanfar; Emily V Capbarat; Youngho Seo
Journal:  Mol Imaging Biol       Date:  2018-06       Impact factor: 3.488

2.  Characterization of Large-Area SiPM Array for PET Applications.

Authors:  Junwei Du; Yongfeng Yang; Xiaowei Bai; Martin S Judenhofer; Eric Berg; Kun Di; Steve Buckley; Carl Jackson; Simon R Cherry
Journal:  IEEE Trans Nucl Sci       Date:  2016-02-15       Impact factor: 1.679

3.  Recent developments in time-of-flight PET.

Authors:  S Vandenberghe; E Mikhaylova; E D'Hoe; P Mollet; J S Karp
Journal:  EJNMMI Phys       Date:  2016-02-16
  3 in total

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