Literature DB >> 21614135

Comparison of Detector Intrinsic Spatial Resolution Characteristics for Sensor on the Entrance Surface and Conventional Readout Designs.

Robert S Miyaoka1, Xiaoli Li, Cate Lockhart, Tom K Lewellen.   

Abstract

We report on a high resolution, monolithic crystal PET detector design concept that provides depth of interaction (DOI) positioning within the crystal. Our design utilizes a novel sensor on the entrance surface (SES) approach combined with a maximum likelihood positioning algorithm. We compare the intrinsic spatial resolution characteristics (i.e., X, Y and Z) using our SES design versus conventional placement of the photo-sensors on the rear surface of the crystal. The sensors can be any two-dimensional array of solid state readout devices (e.g., silicon photomultipliers (SiPM) or avalanche photodiodes (APD)). SiPMs are a new type of solid-state photodetector with Geiger mode operation that can provide signal gain similar to a photomltipiler tube (PMT). Utilizing a multi-step simulation process, we determined the intrinsic spatial resolution characteristics for a variety of detector configurations. The SES design was evaluated via simulation for three different two-dimensional array sizes: 8×8 with 5.8×5.8 mm(2) pads; 12×12 with 3.8×3.8mm(2) pads; and 16×16 with 2.8×2.8 mm(2) pads. To reduce the number of signal channels row-column summing readout was used for the 12×12 and 16×16 channel array devices. The crystal was modeled as a 15 mm monolithic slab of a lutetium-based scintillator with the large area surface varying from 48.8×48.8 mm(2) up to 49.6×49.6 mm(2) depending upon the dimensions of the two-dimensional photo-sensor array. The intrinsic spatial resolution for the 8×8 array is 0.88 mm FWHM in X and Y, and 1.83 mm FWHM in Z (i.e., DOI). Comparing the results versus using a conventional design with the photo-sensors on the backside of the crystal, an average improvement of ~24% in X and Y and 20% in Z is achieved. The X, Y intrinsic spatial resolution improved to 0.67 mm and 0.64 mm FWHM for the 12×12 and 16×16 arrays using row-column readout. Using the 12×12 and 16×16 arrays also led to a slight improvement in the DOI positioning accuracy.

Entities:  

Year:  2010        PMID: 21614135      PMCID: PMC3099648          DOI: 10.1109/TNS.2010.2046675

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  4 in total

1.  MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging.

Authors:  Yuan-Chuan Tai; Arion F Chatziioannou; Yongfeng Yang; Robert W Silverman; Ken Meadors; Stefan Siegel; Danny F Newport; Jennifer R Stickel; Simon R Cherry
Journal:  Phys Med Biol       Date:  2003-06-07       Impact factor: 3.609

2.  Depth of interaction decoding of a continuous crystal detector module.

Authors:  T Ling; T K Lewellen; R S Miyaoka
Journal:  Phys Med Biol       Date:  2007-03-29       Impact factor: 3.609

3.  A novel, SiPM-array-based, monolithic scintillator detector for PET.

Authors:  Dennis R Schaart; Herman T van Dam; Stefan Seifert; Ruud Vinke; Peter Dendooven; Herbert Löhner; Freek J Beekman
Journal:  Phys Med Biol       Date:  2009-05-15       Impact factor: 3.609

4.  Development of a single detector ring micro crystal element scanner: QuickPET II.

Authors:  Robert S Miyaoka; Marie L Janes; Kisung Lee; Byungki Park; Paul E Kinahan; Tom K Lewellen
Journal:  Mol Imaging       Date:  2005 Apr-Jun       Impact factor: 4.488

  4 in total
  11 in total

1.  Performance Evaluation of Small Animal PET Scanners With Different System Designs.

Authors:  Xiaoli Li; Adam M Alessio; Thompson H Burnett; Thomas K Lewellen; Roberts Miyaoka
Journal:  IEEE Trans Nucl Sci       Date:  2013-06       Impact factor: 1.679

2.  Measurements of entrance-surface vs. conventional single-ended readout of a monolithic scintillator.

Authors:  William C J Hunter; Wendy McDougald; Jerome J Griesmer; Lingxiong Shao; Robert Zahn; Tom K Lewellen; Robert S Miyaoka
Journal:  IEEE Trans Nucl Sci       Date:  2011       Impact factor: 1.679

3.  Multiple-hit parameter estimation in monolithic detectors.

Authors:  William C J Hunter; Harrison H Barrett; Tom K Lewellen; Robert S Miyaoka
Journal:  IEEE Trans Med Imaging       Date:  2012-11-10       Impact factor: 10.048

4.  Characterization or Monolithic Scintillation Detectors Etched with Laser Induced Optical Barriers.

Authors:  J V Panetta; S Surti; B Singh; J S Karp
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2018-10-10

5.  Study of PET Detector Performance with Varying SiPM Parameters and Readout Schemes.

Authors:  Xiaoli Li; Cate Lockhart; Tom K Lewellen; Robert S Miyaoka
Journal:  IEEE Trans Nucl Sci       Date:  2011       Impact factor: 1.679

6.  Use of Cramer-Rao Lower Bound for Performance Evaluation of Different Monolithic Crystal PET Detector Designs.

Authors:  Xiaoli Li; William C J Hunter; Tom K Lewellen; Robert S Miyaoka
Journal:  IEEE Trans Nucl Sci       Date:  2012       Impact factor: 1.679

7.  Pulse shape discrimination and classification methods for continuous depth of interaction encoding PET detectors.

Authors:  Emilie Roncali; Jennifer E Phipps; Laura Marcu; Simon R Cherry
Journal:  Phys Med Biol       Date:  2012-09-25       Impact factor: 3.609

Review 8.  Application of silicon photomultipliers to positron emission tomography.

Authors:  Emilie Roncali; Simon R Cherry
Journal:  Ann Biomed Eng       Date:  2011-02-15       Impact factor: 3.934

9.  Resolution Properties of a Prototype Continuous Miniature Crystal Element (cMiCE) Scanner.

Authors:  Robert S Miyaoka; Xiaoli Li; William Hunter; Larry A Pierce; Wendy McDougald; Paul E Kinahan; Thomas K Lewellen
Journal:  IEEE Trans Nucl Sci       Date:  2011-10       Impact factor: 1.679

10.  Modelling the transport of optical photons in scintillation detectors for diagnostic and radiotherapy imaging.

Authors:  Emilie Roncali; Mohammad Amin Mosleh-Shirazi; Aldo Badano
Journal:  Phys Med Biol       Date:  2017-10-04       Impact factor: 3.609

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