Literature DB >> 19351983

The development, validation and application of a multi-detector CT (MDCT) scanner model for assessing organ doses to the pregnant patient and the fetus using Monte Carlo simulations.

J Gu1, B Bednarz, P F Caracappa, X G Xu.   

Abstract

The latest multiple-detector technologies have further increased the popularity of x-ray CT as a diagnostic imaging modality. There is a continuing need to assess the potential radiation risk associated with such rapidly evolving multi-detector CT (MDCT) modalities and scanning protocols. This need can be met by the use of CT source models that are integrated with patient computational phantoms for organ dose calculations. Based on this purpose, this work developed and validated an MDCT scanner using the Monte Carlo method, and meanwhile the pregnant patient phantoms were integrated into the MDCT scanner model for assessment of the dose to the fetus as well as doses to the organs or tissues of the pregnant patient phantom. A Monte Carlo code, MCNPX, was used to simulate the x-ray source including the energy spectrum, filter and scan trajectory. Detailed CT scanner components were specified using an iterative trial-and-error procedure for a GE LightSpeed CT scanner. The scanner model was validated by comparing simulated results against measured CTDI values and dose profiles reported in the literature. The source movement along the helical trajectory was simulated using the pitch of 0.9375 and 1.375, respectively. The validated scanner model was then integrated with phantoms of a pregnant patient in three different gestational periods to calculate organ doses. It was found that the dose to the fetus of the 3 month pregnant patient phantom was 0.13 mGy/100 mAs and 0.57 mGy/100 mAs from the chest and kidney scan, respectively. For the chest scan of the 6 month patient phantom and the 9 month patient phantom, the fetal doses were 0.21 mGy/100 mAs and 0.26 mGy/100 mAs, respectively. The paper also discusses how these fetal dose values can be used to evaluate imaging procedures and to assess risk using recommendations of the report from AAPM Task Group 36. This work demonstrates the ability of modeling and validating an MDCT scanner by the Monte Carlo method, as well as assessing fetal and organ doses by combining the MDCT scanner model and the pregnant patient phantom.

Entities:  

Mesh:

Year:  2009        PMID: 19351983      PMCID: PMC3376893          DOI: 10.1088/0031-9155/54/9/007

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  41 in total

1.  Characteristics of kilovoltage x-ray beams used for cone-beam computed tomography in radiation therapy.

Authors:  George X Ding; Dennis M Duggan; Charles W Coffey
Journal:  Phys Med Biol       Date:  2007-02-27       Impact factor: 3.609

Review 2.  Computed tomography--an increasing source of radiation exposure.

Authors:  David J Brenner; Eric J Hall
Journal:  N Engl J Med       Date:  2007-11-29       Impact factor: 91.245

3.  The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103.

Authors: 
Journal:  Ann ICRP       Date:  2007

4.  Validation of a Monte Carlo tool for patient-specific dose simulations in multi-slice computed tomography.

Authors:  Paul Deak; Marcel van Straten; Paul C Shrimpton; Maria Zankl; Willi A Kalender
Journal:  Eur Radiol       Date:  2007-12-08       Impact factor: 5.315

5.  Early first-trimester fetal radiation dose estimation in 16-MDCT without and with automated tube current modulation.

Authors:  Tracy A Jaffe; Terry T Yoshizumi; Greta I Toncheva; Giao Nguyen; Lynne M Hurwitz; Rendon C Nelson
Journal:  AJR Am J Roentgenol       Date:  2008-04       Impact factor: 3.959

6.  American College of Radiology white paper on radiation dose in medicine.

Authors:  E Stephen Amis; Priscilla F Butler; Kimberly E Applegate; Steven B Birnbaum; Libby F Brateman; James M Hevezi; Fred A Mettler; Richard L Morin; Michael J Pentecost; Geoffrey G Smith; Keith J Strauss; Robert K Zeman
Journal:  J Am Coll Radiol       Date:  2007-05       Impact factor: 5.532

7.  Trends in the use of unenhanced helical CT for acute urinary colic.

Authors:  M Y Chen; R J Zagoria; H S Saunders; R B Dyer
Journal:  AJR Am J Roentgenol       Date:  1999-12       Impact factor: 3.959

8.  Assessment of patient organ doses and effective doses using the VIP-Man adult male phantom for selected cone-beam CT imaging procedures during image guided radiation therapy.

Authors:  Jianwei Gu; Bryan Bednarz; X George Xu; Steve B Jiang
Journal:  Radiat Prot Dosimetry       Date:  2008-07-29       Impact factor: 0.972

9.  Managing patient dose in multi-detector computed tomography(MDCT). ICRP Publication 102.

Authors:  J Valentin
Journal:  Ann ICRP       Date:  2007

10.  Radiation dose to the fetus for pregnant patients undergoing multidetector CT imaging: Monte Carlo simulations estimating fetal dose for a range of gestational age and patient size.

Authors:  Erin Angel; Clinton V Wellnitz; Mitchell M Goodsitt; Nazanin Yaghmai; John J DeMarco; Christopher H Cagnon; James W Sayre; Dianna D Cody; Donna M Stevens; Andrew N Primak; Cynthia H McCollough; Michael F McNitt-Gray
Journal:  Radiology       Date:  2008-10       Impact factor: 11.105

View more
  31 in total

1.  The feasibility of a scanner-independent technique to estimate organ dose from MDCT scans: using CTDIvol to account for differences between scanners.

Authors:  Adam C Turner; Maria Zankl; John J DeMarco; Chris H Cagnon; Di Zhang; Erin Angel; Dianna D Cody; Donna M Stevens; Cynthia H McCollough; Michael F McNitt-Gray
Journal:  Med Phys       Date:  2010-04       Impact factor: 4.071

Review 2.  Risks to the fetus from diagnostic imaging during pregnancy: review and proposal of a clinical protocol.

Authors:  Mafalda Gomes; Alexandra Matias; Filipe Macedo
Journal:  Pediatr Radiol       Date:  2015-08-14

3.  Dosimetric assessment of the exposure of radiotherapy patients due to cone-beam CT procedures.

Authors:  Mariana Baptista; Salvatore Di Maria; Sandra Vieira; Joana Santos; Joana Pereira; Miguel Pereira; Pedro Vaz
Journal:  Radiat Environ Biophys       Date:  2018-11-03       Impact factor: 1.925

4.  A method to acquire CT organ dose map using OSL dosimeters and ATOM anthropomorphic phantoms.

Authors:  Da Zhang; Xinhua Li; Yiming Gao; X George Xu; Bob Liu
Journal:  Med Phys       Date:  2013-08       Impact factor: 4.071

5.  Monte Carlo calculation of patient organ doses from computed tomography.

Authors:  Takeshi Oono; Fujio Araki; Shoya Tsuduki; Keiichi Kawasaki
Journal:  Radiol Phys Technol       Date:  2013-11-30

6.  Pediatric chest and abdominopelvic CT: organ dose estimation based on 42 patient models.

Authors:  Xiaoyu Tian; Xiang Li; W Paul Segars; Erik K Paulson; Donald P Frush; Ehsan Samei
Journal:  Radiology       Date:  2013-10-28       Impact factor: 11.105

7.  Comparing different methods for estimating radiation dose to the conceptus.

Authors:  X Lopez-Rendon; M S Walgraeve; S Woussen; A Dedulle; G Zhang; H Bosmans; F Zanca
Journal:  Eur Radiol       Date:  2016-05-10       Impact factor: 5.315

8.  Monte Carlo calculation of imaging doses from diagnostic multidetector CT and kilovoltage cone-beam CT as part of prostate cancer treatment plans.

Authors:  Aiping Ding; Jianwei Gu; Alexei V Trofimov; X George Xu
Journal:  Med Phys       Date:  2010-12       Impact factor: 4.071

9.  Experimental validation of a method characterizing bow tie filters in CT scanners using a real-time dose probe.

Authors:  Sarah E McKenney; Anita Nosratieh; Dale Gelskey; Kai Yang; Shin-Ying Huang; Lin Chen; John M Boone
Journal:  Med Phys       Date:  2011-03       Impact factor: 4.071

10.  Fetal doses to pregnant patients from CT with tube current modulation calculated using Monte Carlo simulations and realistic phantoms.

Authors:  Jianwei Gu; X George Xu; Peter F Caracappa; Bob Liu
Journal:  Radiat Prot Dosimetry       Date:  2012-12-06       Impact factor: 0.972

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.