Literature DB >> 24126364

Pediatric chest and abdominopelvic CT: organ dose estimation based on 42 patient models.

Xiaoyu Tian1, Xiang Li, W Paul Segars, Erik K Paulson, Donald P Frush, Ehsan Samei.   

Abstract

PURPOSE: To estimate organ dose from pediatric chest and abdominopelvic computed tomography (CT) examinations and evaluate the dependency of organ dose coefficients on patient size and CT scanner models.
MATERIALS AND METHODS: The institutional review board approved this HIPAA-compliant study and did not require informed patient consent. A validated Monte Carlo program was used to perform simulations in 42 pediatric patient models (age range, 0-16 years; weight range, 2-80 kg; 24 boys, 18 girls). Multidetector CT scanners were modeled on those from two commercial manufacturers (LightSpeed VCT, GE Healthcare, Waukesha, Wis; SOMATOM Definition Flash, Siemens Healthcare, Forchheim, Germany). Organ doses were estimated for each patient model for routine chest and abdominopelvic examinations and were normalized by volume CT dose index (CTDI(vol)). The relationships between CTDI(vol)-normalized organ dose coefficients and average patient diameters were evaluated across scanner models.
RESULTS: For organs within the image coverage, CTDI(vol)-normalized organ dose coefficients largely showed a strong exponential relationship with the average patient diameter (R(2) > 0.9). The average percentage differences between the two scanner models were generally within 10%. For distributed organs and organs on the periphery of or outside the image coverage, the differences were generally larger (average, 3%-32%) mainly because of the effect of overranging.
CONCLUSION: It is feasible to estimate patient-specific organ dose for a given examination with the knowledge of patient size and the CTDI(vol). These CTDI(vol)-normalized organ dose coefficients enable one to readily estimate patient-specific organ dose for pediatric patients in clinical settings. This dose information, and, as appropriate, attendant risk estimations, can provide more substantive information for the individual patient for both clinical and research applications and can yield more expansive information on dose profiles across patient populations within a practice. © RSNA, 2013.

Entities:  

Mesh:

Year:  2013        PMID: 24126364      PMCID: PMC4228746          DOI: 10.1148/radiol.13122617

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  21 in total

1.  CT dose index and patient dose: they are not the same thing.

Authors:  Cynthia H McCollough; Shuai Leng; Lifeng Yu; Dianna D Cody; John M Boone; Michael F McNitt-Gray
Journal:  Radiology       Date:  2011-05       Impact factor: 11.105

2.  Estimated risks of radiation-induced fatal cancer from pediatric CT.

Authors:  D Brenner; C Elliston; E Hall; W Berdon
Journal:  AJR Am J Roentgenol       Date:  2001-02       Impact factor: 3.959

3.  Radiation exposure from CT scans: how to close our knowledge gaps, monitor and safeguard exposure--proceedings and recommendations of the Radiation Dose Summit, sponsored by NIBIB, February 24-25, 2011.

Authors:  John M Boone; William R Hendee; Michael F McNitt-Gray; Steven E Seltzer
Journal:  Radiology       Date:  2012-09-10       Impact factor: 11.105

4.  Patient-specific radiation dose and cancer risk for pediatric chest CT.

Authors:  Xiang Li; Ehsan Samei; W Paul Segars; Gregory M Sturgeon; James G Colsher; Donald P Frush
Journal:  Radiology       Date:  2011-04-05       Impact factor: 11.105

5.  Extension of RPI-adult male and female computational phantoms to obese patients and a Monte Carlo study of the effect on CT imaging dose.

Authors:  Aiping Ding; Matthew M Mille; Tianyu Liu; Peter F Caracappa; X George Xu
Journal:  Phys Med Biol       Date:  2012-04-05       Impact factor: 3.609

6.  Organ doses for reference pediatric and adolescent patients undergoing computed tomography estimated by Monte Carlo simulation.

Authors:  Choonsik Lee; Kwang Pyo Kim; Daniel J Long; Wesley E Bolch
Journal:  Med Phys       Date:  2012-04       Impact factor: 4.071

7.  In-plane bismuth breast shields for pediatric CT: effects on radiation dose and image quality using experimental and clinical data.

Authors:  Bradley L Fricke; Lane F Donnelly; Donald P Frush; Terry Yoshizumi; Vladimir Varchena; Stacy A Poe; Javier Lucaya
Journal:  AJR Am J Roentgenol       Date:  2003-02       Impact factor: 3.959

8.  Population of anatomically variable 4D XCAT adult phantoms for imaging research and optimization.

Authors:  W P Segars; Jason Bond; Jack Frush; Sylvia Hon; Chris Eckersley; Cameron H Williams; Jianqiao Feng; Daniel J Tward; J T Ratnanather; M I Miller; D Frush; E Samei
Journal:  Med Phys       Date:  2013-04       Impact factor: 4.071

9.  Dose coefficients in pediatric and adult abdominopelvic CT based on 100 patient models.

Authors:  Xiaoyu Tian; Xiang Li; W Paul Segars; Donald P Frush; Erik K Paulson; Ehsan Samei
Journal:  Phys Med Biol       Date:  2013-12-04       Impact factor: 3.609

10.  Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study.

Authors:  Mark S Pearce; Jane A Salotti; Mark P Little; Kieran McHugh; Choonsik Lee; Kwang Pyo Kim; Nicola L Howe; Cecile M Ronckers; Preetha Rajaraman; Alan W Sir Craft; Louise Parker; Amy Berrington de González
Journal:  Lancet       Date:  2012-06-07       Impact factor: 79.321

View more
  27 in total

1.  The development of a population of 4D pediatric XCAT phantoms for imaging research and optimization.

Authors:  W P Segars; Hannah Norris; Gregory M Sturgeon; Yakun Zhang; Jason Bond; Anum Minhas; Daniel J Tward; J T Ratnanather; M I Miller; D Frush; E Samei
Journal:  Med Phys       Date:  2015-08       Impact factor: 4.071

2.  The impact on CT dose of the variability in tube current modulation technology: a theoretical investigation.

Authors:  Xiang Li; W Paul Segars; Ehsan Samei
Journal:  Phys Med Biol       Date:  2014-07-28       Impact factor: 3.609

3.  Prospective estimation of organ dose in CT under tube current modulation.

Authors:  Xiaoyu Tian; Xiang Li; W Paul Segars; Donald P Frush; Ehsan Samei
Journal:  Med Phys       Date:  2015-04       Impact factor: 4.071

4.  Development of a paediatric head voxel model database for dosimetric applications.

Authors:  Andreas Stratis; Nathan Touyz; Guozhi Zhang; Reinhilde Jacobs; Ria Bogaerts; Hilde Bosmans
Journal:  Br J Radiol       Date:  2017-07-27       Impact factor: 3.039

5.  Extending the concept of weighted CT dose index to elliptical phantoms of various aspect ratios.

Authors:  Andrey Markovich; Ashraf G Morgan; Frank F Dong; Andrew N Primak; Xiang Li
Journal:  J Med Imaging (Bellingham)       Date:  2017-07-05

6.  Accuracy of patient-specific organ dose estimates obtained using an automated image segmentation algorithm.

Authors:  Taly Gilat Schmidt; Adam S Wang; Thomas Coradi; Benjamin Haas; Josh Star-Lack
Journal:  J Med Imaging (Bellingham)       Date:  2016-11-29

7.  Evaluation of Effective Dose from CT Scans for Overweight and Obese Adult Patients Using the VirtualDose Software.

Authors:  Baohui Liang; Yiming Gao; Zhi Chen; X George Xu
Journal:  Radiat Prot Dosimetry       Date:  2017-04-25       Impact factor: 0.972

Review 8.  Application of the 4-D XCAT Phantoms in Biomedical Imaging and Beyond.

Authors:  W Paul Segars; B M W Tsui; George S K Fung; Ehsan Samei
Journal:  IEEE Trans Med Imaging       Date:  2017-08-10       Impact factor: 10.048

9.  Organ doses from CT localizer radiographs: Development, validation, and application of a Monte Carlo estimation technique.

Authors:  Jocelyn Hoye; Shobhit Sharma; Yakun Zhang; Wanyi Fu; Francesco Ria; Anuj Kapadia; W Paul Segars; Joshua Wilson; Ehsan Samei
Journal:  Med Phys       Date:  2019-09-16       Impact factor: 4.071

10.  Radiation risk index for pediatric CT: a patient-derived metric.

Authors:  Ehsan Samei; Xiaoyu Tian; W Paul Segars; Donald P Frush
Journal:  Pediatr Radiol       Date:  2017-08-30
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.