PURPOSE: To investigate the behavior of whole-head and local specific absorption rate (SAR) as a function of trajectory acceleration factor and target excitation pattern due to the parallel transmission (pTX) of spatially tailored excitations at 7T. MATERIALS AND METHODS: Finite-difference time domain (FDTD) simulations in a multitissue head model were used to obtain B(1) (+) and electric field maps of an eight-channel transmit head array. Local and average SAR produced by 2D-spiral-trajectory excitations were examined as a function of trajectory acceleration factor, R, and a variety of target excitation parameters when pTX pulses are designed for constant root-mean-square excitation pattern error. RESULTS: Mean and local SAR grow quadratically with flip angle and more than quadratically with R, but the ratio of local to mean SAR is not monotonic with R. SAR varies greatly with target position, exhibiting different behaviors as a function of target shape and size for small and large R. For example, exciting large regions produces less SAR than exciting small ones for R >or=4, but the opposite trend occurs when R <4. Furthermore, smoother and symmetric patterns produce lower SAR. CONCLUSION: Mean and local SAR vary by orders of magnitude depending on acceleration factor and excitation pattern, often exhibiting complex, nonintuitive behavior. To ensure safety compliance, it seems that model-based validation of individual target patterns and corresponding pTX pulses is necessary. (c) 2008 Wiley-Liss, Inc.
PURPOSE: To investigate the behavior of whole-head and local specific absorption rate (SAR) as a function of trajectory acceleration factor and target excitation pattern due to the parallel transmission (pTX) of spatially tailored excitations at 7T. MATERIALS AND METHODS: Finite-difference time domain (FDTD) simulations in a multitissue head model were used to obtain B(1) (+) and electric field maps of an eight-channel transmit head array. Local and average SAR produced by 2D-spiral-trajectory excitations were examined as a function of trajectory acceleration factor, R, and a variety of target excitation parameters when pTX pulses are designed for constant root-mean-square excitation pattern error. RESULTS: Mean and local SAR grow quadratically with flip angle and more than quadratically with R, but the ratio of local to mean SAR is not monotonic with R. SAR varies greatly with target position, exhibiting different behaviors as a function of target shape and size for small and large R. For example, exciting large regions produces less SAR than exciting small ones for R >or=4, but the opposite trend occurs when R <4. Furthermore, smoother and symmetric patterns produce lower SAR. CONCLUSION: Mean and local SAR vary by orders of magnitude depending on acceleration factor and excitation pattern, often exhibiting complex, nonintuitive behavior. To ensure safety compliance, it seems that model-based validation of individual target patterns and corresponding pTX pulses is necessary. (c) 2008 Wiley-Liss, Inc.
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