Literature DB >> 1426150

The presence of free D-serine, D-alanine and D-proline in human plasma.

Y Nagata1, R Masui, T Akino.   

Abstract

Twelve neutral free amino acids, i.e. serine, threonine, glutamine, asparagine, alanine, proline, methionine, tyrosine, valine, leucine, isoleucine and phenylalanine, were surveyed for the presence of D-enantiomers in plasma samples from patients with renal diseases and from normal subjects. D-serine, D-alanine and D-proline were found in the patient's plasma. The highest concentrations (D/L ratio) of D-serine, D-alanine and D-proline were 0.2362, 0.2087 and 0.0986, respectively. The sum of the contents of the three D-amino acid was shown to be present in the plasma proteins.

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Year:  1992        PMID： 1426150     DOI： 10.1007/bf01919147

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

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4.  Distribution of two aminotransferases and D-amino acid oxidase within the nephron of young and adult rats.

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Journal:  J Histochem Cytochem       Date:  1979-03       Impact factor: 2.479

5.  D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis.

Authors:  F A Carone; C E Ganote
Journal:  Arch Pathol       Date:  1975-12

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Authors:  Y Nagata; R Konno; Y Yasumura; T Akino
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

7.  Microdetermination of serum D-amino acids.

Authors:  Y Nagata; T Akino; K Ohno
Journal:  Anal Biochem       Date:  1985-10       Impact factor: 3.365

8.  Accumulation of D-aspartic acid with age in the human brain.

Authors:  E H Man; M E Sandhouse; J Burg; G H Fisher
Journal:  Science       Date:  1983-06-24       Impact factor: 47.728

9.  Free D-amino acids in human plasma in relation to senescence and renal diseases.

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Journal:  Clin Sci (Lond)       Date:  1987-07       Impact factor: 6.124

10.  Aspartic acid racemization in tooth enamel from living humans.

Authors:  P M Helfman; J L Bada
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205
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  16 in total

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5.  Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes.

Authors:  Wouter F Visser; Nanda M Verhoeven-Duif; Tom J de Koning
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Review 6.  Chiral secondary amino acids, their importance, and methods of analysis.

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7.  A trial to determine D-amino acids in tissue proteins of mice.

Authors:  Y Nagata; K Kubota
Journal:  Amino Acids       Date:  1993-02       Impact factor: 3.520

8.  Pathogenicity and immunogenicity of a Listeria monocytogenes strain that requires D-alanine for growth.

Authors:  R J Thompson; H G Bouwer; D A Portnoy; F R Frankel
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9.  D-Amino acids in chronic renal failure and the effects of dialysis and urinary losses.

Authors:  G A Young; S Kendall; A M Brownjohn
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10.  Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker.

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