Literature DB >> 24319305

A large area, silicon photomultiplier-based PET detector module.

Rr Raylman1, A Stolin, S Majewski, J Proffitt.   

Abstract

The introduction of silicon photomultipliers (SiPM) has facilitated construction of compact, efficient and magnetic field-hardened positron emission tomography (PET) scanners. To take full advantage of these devices, methods for using them to produce large field-of-view PET scanners are needed. In this investigation, we explored techniques to combine two SiPM arrays to form the building block for a small animal PET scanner. The module consists of a 26 × 58 array of 1.5 × 1.5mm2 LYSO elements (spanning 41 × 91mm2) coupled to two SensL SiPM arrays. The SiPMs were read out with new multiplexing electronics developed for this project. To facilitate calculation of event position with multiple SiPM arrays it was necessary to spread scintillation light amongst a number of elements with a small light guide. This method was successful in permitting identification of all detector elements, even at the seam between two SiPM arrays. Since the performance of SiPMs is enhanced by cooling, the detector module was fitted with a cooling jacket, which allowed the temperature of the device and electronics to be controlled. Testing demonstrated that the peak-to-valley contrast ratio of the light detected from the scintillation array was increased by ∼45% when the temperature was reduced from 28 °C to 16 °C. Energy resolution for 511 keV photons improved slightly from 18.8% at 28 °C to 17.8% at 16 °C. Finally, the coincidence timing resolution of the module was found to be insufficient for time-of-flight applications (∼2100 ps at 14 °C). The first use of these new modules will be in the construction of a small animal PET scanner to be integrated with a 3T clinical magnetic resonance imaging scanner.

Entities:  

Keywords:  Nuclear Medicine Instrumentation; PET; Silicon Photomultipliers

Year:  2014        PMID: 24319305      PMCID: PMC3849045          DOI: 10.1016/j.nima.2013.10.008

Source DB:  PubMed          Journal:  Nucl Instrum Methods Phys Res A        ISSN: 0168-9002            Impact factor:   1.455


  7 in total

1.  Initial results of simultaneous PET/MRI experiments with an MRI-compatible silicon photomultiplier PET scanner.

Authors:  Hyun Suk Yoon; Guen Bae Ko; Sun Il Kwon; Chan Mi Lee; Mikiko Ito; In Chan Song; Dong Soo Lee; Seong Jong Hong; Jae Sung Lee
Journal:  J Nucl Med       Date:  2012-03-13       Impact factor: 10.057

2.  Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI.

Authors:  Bernd J Pichler; Martin S Judenhofer; Ciprian Catana; Jeffrey H Walton; Manfred Kneilling; Robert E Nutt; Stefan B Siegel; Claus D Claussen; Simon R Cherry
Journal:  J Nucl Med       Date:  2006-04       Impact factor: 10.057

3.  A novel, SiPM-array-based, monolithic scintillator detector for PET.

Authors:  Dennis R Schaart; Herman T van Dam; Stefan Seifert; Ruud Vinke; Peter Dendooven; Herbert Löhner; Freek J Beekman
Journal:  Phys Med Biol       Date:  2009-05-15       Impact factor: 3.609

4.  Sub-200 ps CRT in monolithic scintillator PET detectors using digital SiPM arrays and maximum likelihood interaction time estimation.

Authors:  Herman T van Dam; Giacomo Borghi; Stefan Seifert; Dennis R Schaart
Journal:  Phys Med Biol       Date:  2013-04-24       Impact factor: 3.609

5.  Positron emission tomography within a magnetic field using photomultiplier tubes and lightguides.

Authors:  N L Christensen; B E Hammer; B G Heil; K Fetterly
Journal:  Phys Med Biol       Date:  1995-04       Impact factor: 3.609

6.  Development of a Si-PM-based high-resolution PET system for small animals.

Authors:  Seiichi Yamamoto; Masao Imaizumi; Tadashi Watabe; Hiroshi Watabe; Yasukazu Kanai; Eku Shimosegawa; Jun Hatazawa
Journal:  Phys Med Biol       Date:  2010-09-16       Impact factor: 3.609

Review 7.  Application of silicon photomultipliers to positron emission tomography.

Authors:  Emilie Roncali; Simon R Cherry
Journal:  Ann Biomed Eng       Date:  2011-02-15       Impact factor: 3.934

  7 in total
  8 in total

1.  Small animal, positron emission tomography-magnetic resonance imaging system based on a clinical magnetic resonance imaging scanner: evaluation of basic imaging performance.

Authors:  Raymond R Raylman; Patrick Ledden; Alexander V Stolin; Bob Hou; Ganghadar Jaliparthi; Peter F Martone
Journal:  J Med Imaging (Bellingham)       Date:  2018-09-08

2.  Preclinical positron emission tomography scanner based on a monolithic annulus of scintillator: initial design study.

Authors:  Alexander V Stolin; Peter F Martone; Gangadhar Jaliparthi; Raymond R Raylman
Journal:  J Med Imaging (Bellingham)       Date:  2017-01-05

3.  Thermal regulation of tightly packed solid-state photodetectors in a 1 mm(3) resolution clinical PET system.

Authors:  D L Freese; A Vandenbroucke; D Innes; F W Y Lau; D F C Hsu; P D Reynolds; Craig S Levin
Journal:  Med Phys       Date:  2015-01       Impact factor: 4.071

4.  Parameter-Transferred Wasserstein Generative Adversarial Network (PT-WGAN) for Low-Dose PET Image Denoising.

Authors:  Yu Gong; Hongming Shan; Yueyang Teng; Ning Tu; Ming Li; Guodong Liang; Ge Wang; Shanshan Wang
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2020-09-21

5.  Characterization of Large-Area SiPM Array for PET Applications.

Authors:  Junwei Du; Yongfeng Yang; Xiaowei Bai; Martin S Judenhofer; Eric Berg; Kun Di; Steve Buckley; Carl Jackson; Simon R Cherry
Journal:  IEEE Trans Nucl Sci       Date:  2016-02-15       Impact factor: 1.679

6.  Evaluation of a high resolution silicon PET insert module.

Authors:  Milan Grkovski; Karol Brzezinski; Vladimir Cindro; Neal H Clinthorne; Harris Kagan; Carlos Lacasta; Marko Mikuž; Carles Solaz; Andrej Studen; Peter Weilhammer; Dejan Žontar
Journal:  Nucl Instrum Methods Phys Res A       Date:  2015-04-08       Impact factor: 1.455

7.  Impact of event positioning algorithm on performance of a whole-body PET scanner using one-to-one coupled detectors.

Authors:  S Surti; J S Karp
Journal:  Phys Med Biol       Date:  2018-03-02       Impact factor: 3.609

Review 8.  Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.

Authors:  Haewook Park; Minseok Yi; Jae Sung Lee
Journal:  Biomed Eng Lett       Date:  2022-07-16
  8 in total

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