| Literature DB >> 33173251 |
Milan Grkovski1,2, Karol Brzezinski3, Vladimir Cindro1, Neal H Clinthorne4, Harris Kagan5, Carlos Lacasta3, Marko Mikuž1, Carles Solaz3, Andrej Studen1, Peter Weilhammer5, Dejan Žontar1.
Abstract
Conventional PET systems can be augmented with additional detectors placed in close proximity of the region of interest. We developed a high resolution PET insert module to evaluate the added benefit of such a combination. The insert module consists of two back-to-back 1 mm thick silicon sensors, each segmented into 1040 1 mm2 pads arranged in a 40 by 26 array. A set of 16 VATAGP7.1 ASICs and a custom assembled data acquisition board were used to read out the signal from the insert module. Data were acquired in slice (2D) geometry with a Jaszczak phantom (rod diameters of 1.2-4.8 mm) filled with 18F-FDG and the images were reconstructed with ML-EM method. Both data with full and limited angular coverage from the insert module were considered and three types of coincidence events were combined. The ratio of high-resolution data that substantially improves quality of the reconstructed image for the region near the surface of the insert module was estimated to be about 4%. Results from our previous studies suggest that such ratio could be achieved at a moderate technological expense by using an equivalent of two insert modules (an effective sensor thickness of 4 mm).Entities:
Keywords: Image reconstruction; PET insert; Positron emission tomography; Silicon detectors
Year: 2015 PMID: 33173251 PMCID: PMC7650022 DOI: 10.1016/j.nima.2015.03.078
Source DB: PubMed Journal: Nucl Instrum Methods Phys Res A ISSN: 0168-9002 Impact factor: 1.455