Literature DB >> 33173251

Evaluation of a high resolution silicon PET insert module.

Milan Grkovski1,2, Karol Brzezinski3, Vladimir Cindro1, Neal H Clinthorne4, Harris Kagan5, Carlos Lacasta3, Marko Mikuž1, Carles Solaz3, Andrej Studen1, Peter Weilhammer5, Dejan Žontar1.   

Abstract

Conventional PET systems can be augmented with additional detectors placed in close proximity of the region of interest. We developed a high resolution PET insert module to evaluate the added benefit of such a combination. The insert module consists of two back-to-back 1 mm thick silicon sensors, each segmented into 1040 1 mm2 pads arranged in a 40 by 26 array. A set of 16 VATAGP7.1 ASICs and a custom assembled data acquisition board were used to read out the signal from the insert module. Data were acquired in slice (2D) geometry with a Jaszczak phantom (rod diameters of 1.2-4.8 mm) filled with 18F-FDG and the images were reconstructed with ML-EM method. Both data with full and limited angular coverage from the insert module were considered and three types of coincidence events were combined. The ratio of high-resolution data that substantially improves quality of the reconstructed image for the region near the surface of the insert module was estimated to be about 4%. Results from our previous studies suggest that such ratio could be achieved at a moderate technological expense by using an equivalent of two insert modules (an effective sensor thickness of 4 mm).

Entities:  

Keywords:  Image reconstruction; PET insert; Positron emission tomography; Silicon detectors

Year:  2015        PMID: 33173251      PMCID: PMC7650022          DOI: 10.1016/j.nima.2015.03.078

Source DB:  PubMed          Journal:  Nucl Instrum Methods Phys Res A        ISSN: 0168-9002            Impact factor:   1.455


  22 in total

1.  Improving PET imaging for breast cancer using virtual pinhole PET half-ring insert.

Authors:  Aswin John Mathews; Sergey Komarov; Heyu Wu; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  Phys Med Biol       Date:  2013-09-02       Impact factor: 3.609

2.  Virtual-pinhole PET.

Authors:  Yuan-Chuan Tai; Heyu Wu; Debashish Pal; Joseph A O'Sullivan
Journal:  J Nucl Med       Date:  2008-02-20       Impact factor: 10.057

3.  A feasibility study of a prototype PET insert device to convert a general-purpose animal PET scanner to higher resolution.

Authors:  Heyu Wu; Debashish Pal; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  J Nucl Med       Date:  2007-12-12       Impact factor: 10.057

4.  Theoretical analysis and simulation study of a high-resolution zoom-in PET system.

Authors:  Jian Zhou; Jinyi Qi
Journal:  Phys Med Biol       Date:  2009-08-11       Impact factor: 3.609

5.  Timing performance of the silicon PET insert probe.

Authors:  A Studen; D Burdette; E Chesi; V Cindro; N H Clinthorne; E Cochran; B Grosicar; H Kagan; C Lacasta; V Linhart; M Mikuz; V Stankova; P Weilhammer; D Zontar
Journal:  Radiat Prot Dosimetry       Date:  2010-03-09       Impact factor: 0.972

6.  Experimental assessment of resolution improvement of a zoom-in PET.

Authors:  Jinyi Qi; Yongfeng Yang; Jian Zhou; Yibao Wu; Simon R Cherry
Journal:  Phys Med Biol       Date:  2011-08-09       Impact factor: 3.609

7.  Fundamental Limits of Spatial Resolution in PET.

Authors:  William W Moses
Journal:  Nucl Instrum Methods Phys Res A       Date:  2011-08-21       Impact factor: 1.455

8.  Construction and Evaluation of a Prototype High Resolution, Silicon Photomultiplier-Based, Tandem Positron Emission Tomography System.

Authors:  Alexander V Stolin; Stan Majewski; Gangadhar Jaliparthi; Raymond R Raylman
Journal:  IEEE Trans Nucl Sci       Date:  2013-02       Impact factor: 1.679

9.  Design study of a high-resolution breast-dedicated PET system built from cadmium zinc telluride detectors.

Authors:  Hao Peng; Craig S Levin
Journal:  Phys Med Biol       Date:  2010-04-19       Impact factor: 3.609

Review 10.  Tumor quantification in clinical positron emission tomography.

Authors:  Bing Bai; James Bading; Peter S Conti
Journal:  Theranostics       Date:  2013-10-07       Impact factor: 11.556

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  1 in total

1.  System resolution versus image uncertainty for positron emission tomography scanners.

Authors:  Andrej Studen; Neal Clinthorne
Journal:  J Med Imaging (Bellingham)       Date:  2022-05-13
  1 in total

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