Literature DB >> 17238396

Re-identification of familial database records.

Bradley Malin1.   

Abstract

Many genome-based research projects include familial relationships, such as pedigrees, with genomic data records. To protect anonymity when sharing family information, data holders remove, or encode, explicit identifiers (e.g. personal name). In this paper, however, we introduce IdentiFamily, a software program that can link de-identified family relations to named people. The program extracts genealogical knowledge from publicly available records and ascertains the re-identification risk for specific family relations. We find robust genealogies on current populations can be extracted from online sources, such as newspaper obituaries and death records. We evaluate IdentiFamily on real world data for a state's capital city and demonstrate unique identifiability for approximately 70% of the population. IdentiFamily provides organizations with a tool to evaluate the anonymity of pedigrees prior to disclosure and design formal privacy protection techniques.

Entities:  

Mesh:

Year:  2006        PMID: 17238396      PMCID: PMC1839550     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  13 in total

1.  Procedure to protect confidentiality of familial data in community genetics and genomic research.

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2.  Determining the identifiability of DNA database entries.

Authors:  B Malin; L Sweeney
Journal:  Proc AMIA Symp       Date:  2000

3.  The Zipper: a method for using personal identifiers to link data while preserving confidentiality.

Authors:  R L Kruse; B G Ewigman; G C Tremblay
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4.  Establishment of a method of anonymization of DNA samples in genetic research.

Authors:  Kazuo Hara; Kazuhiko Ohe; Takashi Kadowaki; Naoya Kato; Yasushi Imai; Katsushi Tokunaga; Ryozo Nagai; Masao Omata
Journal:  J Hum Genet       Date:  2003-05-15       Impact factor: 3.172

5.  How (not) to protect genomic data privacy in a distributed network: using trail re-identification to evaluate and design anonymity protection systems.

Authors:  Bradley Malin; Latanya Sweeney
Journal:  J Biomed Inform       Date:  2004-06       Impact factor: 6.317

6.  Genetics. Genomic research and human subject privacy.

Authors:  Zhen Lin; Art B Owen; Russ B Altman
Journal:  Science       Date:  2004-07-09       Impact factor: 47.728

7.  An evaluation of the current state of genomic data privacy protection technology and a roadmap for the future.

Authors:  Bradley A Malin
Journal:  J Am Med Inform Assoc       Date:  2004-10-18       Impact factor: 4.497

8.  Integration of genomic data in Electronic Health Records--opportunities and dilemmas.

Authors:  U Sax; S Schmidt
Journal:  Methods Inf Med       Date:  2005       Impact factor: 2.176

9.  DNA markers for nervous system diseases.

Authors:  J F Gusella; R E Tanzi; M A Anderson; W Hobbs; K Gibbons; R Raschtchian; T C Gilliam; M R Wallace; N S Wexler; P M Conneally
Journal:  Science       Date:  1984-09-21       Impact factor: 47.728

10.  Protection of privacy by third-party encryption in genetic research in Iceland.

Authors:  J R Gulcher; K Kristjánsson; H Gudbjartsson; K Stefánsson
Journal:  Eur J Hum Genet       Date:  2000-10       Impact factor: 4.246

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  22 in total

1.  Preserving temporal relations in clinical data while maintaining privacy.

Authors:  George Hripcsak; Parsa Mirhaji; Alexander Fh Low; Bradley A Malin
Journal:  J Am Med Inform Assoc       Date:  2016-03-24       Impact factor: 4.497

2.  Is deidentification sufficient to protect health privacy in research?

Authors:  Mark A Rothstein
Journal:  Am J Bioeth       Date:  2010-09       Impact factor: 11.229

3.  Reducing patient re-identification risk for laboratory results within research datasets.

Authors:  Ravi V Atreya; Joshua C Smith; Allison B McCoy; Bradley Malin; Randolph A Miller
Journal:  J Am Med Inform Assoc       Date:  2012-07-21       Impact factor: 4.497

4.  Genetic data sharing and privacy.

Authors:  Marco D Sorani; John K Yue; Sourabh Sharma; Geoffrey T Manley; Adam R Ferguson
Journal:  Neuroinformatics       Date:  2015-01

5.  Eyes wide open: the personal genome project, citizen science and veracity in informed consent.

Authors:  Misha Angrist
Journal:  Per Med       Date:  2009-11       Impact factor: 2.512

Review 6.  Routes for breaching and protecting genetic privacy.

Authors:  Yaniv Erlich; Arvind Narayanan
Journal:  Nat Rev Genet       Date:  2014-05-08       Impact factor: 53.242

7.  Technical and policy approaches to balancing patient privacy and data sharing in clinical and translational research.

Authors:  Bradley Malin; David Karp; Richard H Scheuermann
Journal:  J Investig Med       Date:  2010-01       Impact factor: 2.895

8.  Privacy in the Genomic Era.

Authors:  Muhammad Naveed; Erman Ayday; Ellen W Clayton; Jacques Fellay; Carl A Gunter; Jean-Pierre Hubaux; Bradley A Malin; Xiaofeng Wang
Journal:  ACM Comput Surv       Date:  2015-09       Impact factor: 10.282

9.  Addressing Benefits, Risks and Consent in Next Generation Sequencing Studies.

Authors:  R Meller
Journal:  J Clin Res Bioeth       Date:  2015-12-14

10.  Confronting real time ethical, legal, and social issues in the Electronic Medical Records and Genomics (eMERGE) Consortium.

Authors:  Ellen Wright Clayton; Maureen Smith; Stephanie M Fullerton; Wylie Burke; Catherine A McCarty; Barbara A Koenig; Amy L McGuire; Laura M Beskow; Lynn Dressler; Amy A Lemke; Erin M Ramos; Laura Lyman Rodriguez
Journal:  Genet Med       Date:  2010-10       Impact factor: 8.822

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