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Literature DB >> 6180119

Multiple human beta interferon genes.

A D Sagar, P B Sehgal, D L Slate, F H Ruddle.

Abstract

Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. The results obtained are consistent with the existence of IFN-beta genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1982 PMID： 6180119 PMCID： PMC2186800 DOI： 10.1084/jem.156.3.744

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

37 in total

1. The somatic cell genetics of human interferon: assignment of human interferon loci to chromosomes 2 and 5.

Authors: Y H Tan; R P Creagan; F H Ruddle
Journal: Proc Natl Acad Sci U S A Date: 1974-06 Impact factor: 11.205

2. Production of high-titered interferon in cultures of human diploid cells.

Authors: E A Havell; J Vilcek
Journal: Antimicrob Agents Chemother Date: 1972-12 Impact factor: 5.191

3. Molecular cloning of human interferon cDNA.

Authors: T Taniguchi; Y Fujii-Kuriyama; M Muramatsu
Journal: Proc Natl Acad Sci U S A Date: 1980-07 Impact factor: 11.205

4. Synthesis of human fibroblast interferon by E. coli.

Authors: D V Goeddel; H M Shepard; E Yelverton; D Leung; R Crea; A Sloma; S Pestka
Journal: Nucleic Acids Res Date: 1980-09-25 Impact factor: 16.971

5. Nucleotide sequence of the chromosomal gene for human fibroblast (beta 1) interferon and of the flanking regions.

Authors: W Degrave; R Derynck; J Tavernier; G Haegeman; W Fiers
Journal: Gene Date: 1981-08 Impact factor: 3.688

6. Leukocyte and fibroblast interferon genes are located on human chromosome 9.

Authors: D Owerbach; W J Rutter; T B Shows; P Gray; D V Goeddel; R M Lawn
Journal: Proc Natl Acad Sci U S A Date: 1981-05 Impact factor: 11.205

7. Human fibroblast interferon gene lacks introns.

Authors: R M Lawn; J Adelman; A E Franke; C M Houck; M Gross; R Najarian; D V Goeddel
Journal: Nucleic Acids Res Date: 1981-03-11 Impact factor: 16.971

8. Human leukocyte interferon produced by E. coli is biologically active.

Authors: D V Goeddel; E Yelverton; A Ullrich; H L Heyneker; G Miozzari; W Holmes; P H Seeburg; T Dull; L May; N Stebbing; R Crea; S Maeda; R McCandliss; A Sloma; J M Tabor; M Gross; P C Familletti; S Pestka
Journal: Nature Date: 1980-10-02 Impact factor: 49.962

9. The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase.

Authors: M Houghton; M A Easton; A G Stewart; J C Smith; S M Doel; G H Catlin; H M Lewis; T P Patel; J S Emtage; N H Carey; A G Porter
Journal: Nucleic Acids Res Date: 1980-07-11 Impact factor: 16.971

10. Human beta interferon gene localization and expression in somatic cell hybrids.

Authors: P M Pitha; D L Slate; N B Raj; F H Ruddle
Journal: Mol Cell Biol Date: 1982-05 Impact factor: 4.272

11 in total

1. Unusually long mRNA species coding for human alpha and beta interferons.

Authors: P B Sehgal; L T May; K S LaForge; M Inouye
Journal: Proc Natl Acad Sci U S A Date: 1982-11 Impact factor: 11.205

2. Human chromosome 7 carries the beta 2 interferon gene.

Authors: P B Sehgal; A Zilberstein; R M Ruggieri; L T May; A Ferguson-Smith; D L Slate; M Revel; F H Ruddle
Journal: Proc Natl Acad Sci U S A Date: 1986-07 Impact factor: 11.205

3. Anti-beta-interferon antibodies inhibit the increased expression of HLA-B7 mRNA in tumor necrosis factor-treated human fibroblasts: structural studies of the beta 2 interferon involved.

Authors: L T May; D C Helfgott; P B Sehgal
Journal: Proc Natl Acad Sci U S A Date: 1986-12 Impact factor: 11.205

4. Structure and expression in Escherichia coli of a cloned rat interferon-alpha gene.

Authors: R Dijkema; P Pouwels; A de Reus; H Schellekens
Journal: Nucleic Acids Res Date: 1984-01-25 Impact factor: 16.971

5. Lactoferrin release and interleukin-1, interleukin-6, and tumor necrosis factor production by human polymorphonuclear cells stimulated by various lipopolysaccharides: relationship to growth inhibition of Candida albicans.

Authors: C Palma; A Cassone; D Serbousek; C A Pearson; J Y Djeu
Journal: Infect Immun Date: 1992-11 Impact factor: 3.441

Review 6. The interferons.

Authors: J L Toy
Journal: Clin Exp Immunol Date: 1983-10 Impact factor: 4.330

7. A cytokine network in human diploid fibroblasts: interactions of beta-interferons, tumor necrosis factor, platelet-derived growth factor, and interleukin-1.

Authors: M Kohase; L T May; I Tamm; J Vilcek; P B Sehgal
Journal: Mol Cell Biol Date: 1987-01 Impact factor: 4.272