Literature DB >> 6193915

The interferons.

J L Toy.   

Abstract

An overview of the interferons is presented. A description of something of what is known about them is given, including: their genes; their protein structures and characteristics; their mechanisms of actions; and their varied biological effects emphasising particularly their immunomodulatory actions. Finally, a brief summary is made of the current status of human clinical studies that have been conducted with interferons in the oncological and viral fields, mentioning also recent findings in patients who have the acquired immunodeficiency syndrome (AIDS).

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Year:  1983        PMID: 6193915      PMCID: PMC1536188     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN: 0009-9104            Impact factor:   4.330


  121 in total

1.  Interferon-the first quarter century.

Authors:  T C Merigan
Journal:  JAMA       Date:  1982-11-19       Impact factor: 56.272

Review 2.  Biochemistry of interferons and their actions.

Authors:  P Lengyel
Journal:  Annu Rev Biochem       Date:  1982       Impact factor: 23.643

3.  Acid-labile human leukocyte interferon in homosexual men with Kaposi's sarcoma and lymphadenopathy.

Authors:  E DeStefano; R M Friedman; A E Friedman-Kien; J J Goedert; D Henriksen; O T Preble; J A Sonnabend; J Vilcek
Journal:  J Infect Dis       Date:  1982-10       Impact factor: 5.226

4.  Human leukocyte interferon and cimetidine for metastatic melanoma.

Authors:  S Borgström; F E von Eyben; P Flodgren; B Axelsson; H O Sjögren
Journal:  N Engl J Med       Date:  1982-10-21       Impact factor: 91.245

5.  Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells.

Authors:  D Wallach; M Fellous; M Revel
Journal:  Nature       Date:  1982-10-28       Impact factor: 49.962

6.  Effects of interferon-alpha on human warts.

Authors:  G J Pazin; M Ho; H W Haverkos; J A Armstrong; M C Breinig; H L Wechsler; A Arvin; T C Merigan; K Cantell
Journal:  J Interferon Res       Date:  1982

7.  Effect of interferon therapy on circulating lymphocytes in humans.

Authors:  L Rasmussen; T C Merigan
Journal:  J Interferon Res       Date:  1980

8.  Heterogeneity of human gamma interferon preparations: evidence for presence of alpha interferon.

Authors:  M Wiranowska-Stewart
Journal:  J Interferon Res       Date:  1981-02

9.  Structure of the human immune interferon gene.

Authors:  P W Gray; D V Goeddel
Journal:  Nature       Date:  1982-08-26       Impact factor: 49.962

10.  Multiple human beta interferon genes.

Authors:  A D Sagar; P B Sehgal; D L Slate; F H Ruddle
Journal:  J Exp Med       Date:  1982-09-01       Impact factor: 14.307

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  16 in total

1.  Recombinant interferon-alpha, but not interferon-gamma is effective therapy for essential thrombocythemia.

Authors:  M J Abegg-Werter; J M Raemaekers; B E de Pauw; C Haanen
Journal:  Blut       Date:  1990-01

2.  A toxicity study of recombinant interferon-gamma given by intravenous infusion to patients with advanced cancer.

Authors:  K Sriskandan; P Garner; J Watkinson; K W Pettingale; D Brinkley; F M Calman; D E Tee
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

3.  Human macrophage activation. Modulation of mannosyl, fucosyl receptor activity in vitro by lymphokines, gamma and alpha interferons, and dexamethasone.

Authors:  T Mokoena; S Gordon
Journal:  J Clin Invest       Date:  1985-02       Impact factor: 14.808

4.  Autoimmune haemolytic anaemia associated with interferon alfa-2a in a patient with mycosis fungoides.

Authors:  L R Braathen; P Stavem
Journal:  BMJ       Date:  1989-06-24

Review 5.  Viewpoint on the impact of interferon in the treatment of multiple myeloma: benefit for a small proportion of patients?

Authors:  J Bladé; J Esteve
Journal:  Med Oncol       Date:  2000-05       Impact factor: 3.064

6.  Interference of hepatitis B virus surface antigen with natural killer cell function.

Authors:  M de Martino; M E Rossi; A T Muccioli; M Resti; A Vierucci
Journal:  Clin Exp Immunol       Date:  1985-07       Impact factor: 4.330

7.  Suppression of foreign body granuloma by recombinant interferon.

Authors:  A Nethersell; K Sikora; T Wheeler; P Conn
Journal:  Br Med J (Clin Res Ed)       Date:  1984-06-30

8.  Effect of interferon gamma and tumour necrosis factor alpha on sensitivity to cisplatin in ovarian carcinoma cell lines.

Authors:  S Clark; M A McGuckin; T Hurst; B G Ward
Journal:  Cancer Immunol Immunother       Date:  1994-08       Impact factor: 6.968

9.  Relationship of HLA protein display to activation of 2-5A synthetase in HBe antigen or anti-HBe positive chronic HBV infection.

Authors:  T Ikeda; M Pignatelli; A M Lever; H C Thomas
Journal:  Gut       Date:  1986-12       Impact factor: 23.059

10.  Cell-mediated immunity in patients with chronic fatigue syndrome, healthy control subjects and patients with major depression.

Authors:  A Lloyd; I Hickie; C Hickie; J Dwyer; D Wakefield
Journal:  Clin Exp Immunol       Date:  1992-01       Impact factor: 4.330

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