Literature DB >> 6169589

Nucleotide sequence of the chromosomal gene for human fibroblast (beta 1) interferon and of the flanking regions.

W Degrave, R Derynck, J Tavernier, G Haegeman, W Fiers.   

Abstract

The nucleotide sequence of the human fibroblast (beta 1) interferon chromosomal gene and its flanking regions was determined. These results confirm the absence of intervening sequences in the gene. The presence of some sequences in the upstream flanking region homologous to similar features for other eukaryotic genes was revealed: these include not only the TATAAAT sequence and the consensus sequence (reported by Benoist et al., 1980) but also two additional motifs, one of which is so far present only in inducible genes. Furthermore, a striking similarity between the upstream flanking regions of the human beta 1 and alpha 1 interferon genes is observed.

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Year:  1981        PMID： 6169589     DOI： 10.1016/0378-1119(81)90109-8

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  21 in total

1.  Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides.

Authors:  D J Capon; H M Shepard; D V Goeddel
Journal:  Mol Cell Biol       Date:  1985-04       Impact factor: 4.272

2.  A human IFN-beta 1 gene deleted of promoter sequences upstream from the TATA box is controlled post-transcriptionally by dsRNA.

Authors:  U Nir; B Cohen; L Chen; M Revel
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

3.  Inducer-responsive expression of the cloned human interferon beta 1 gene introduced into cultured mouse cells.

Authors:  S Ohno; T Taniguchi
Journal:  Nucleic Acids Res       Date:  1982-02-11       Impact factor: 16.971

4.  Organization, structure and expression of murine interferon alpha genes.

Authors:  E C Zwarthoff; A T Mooren; J Trapman
Journal:  Nucleic Acids Res       Date:  1985-02-11       Impact factor: 16.971

5.  Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells.

Authors:  D Canaani; P Berg
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

6.  Induction of human beta-interferon synthesis with poly(rI . rC) in mouse cells transfected with cloned cDNA plasmids.

Authors:  P M Pitha; D M Ciufo; M Kellum; N B Raj; G R Reyes; G S Hayward
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

7.  Human fibroblast interferon RNA transcripts of different sizes in poly(I).poly(C) induced cells.

Authors:  J Content; L De Wit; J Tavernier; W Fiers
Journal:  Nucleic Acids Res       Date:  1983-05-11       Impact factor: 16.971

8.  Molecular cloning of the imidazoleglycerolphosphate dehydratase gene of Trichoderma harzianum by genetic complementation in Saccharomyces cerevisiae using a direct expression vector.

Authors:  G H Goldman; J Demolder; S Dewaele; A Herrera-Estrella; R A Geremia; M Van Montagu; R Contreras
Journal:  Mol Gen Genet       Date:  1992-09

9.  The complete nucleotide sequence of the chick a-actin gene and its evolutionary relationship to the actin gene family.

Authors:  J A Fornwald; G Kuncio; I Peng; C P Ordahl
Journal:  Nucleic Acids Res       Date:  1982-07-10       Impact factor: 16.971

10.  The primary structure of the larval beta 1-globin gene of Xenopus laevis and its flanking regions.

Authors:  W Meyerhof; S Klinger-Mitropoulos; J Stalder; R Weber; W Knöchel
Journal:  Nucleic Acids Res       Date:  1984-10-25       Impact factor: 16.971
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