Literature DB >> 6180309

Human beta interferon gene localization and expression in somatic cell hybrids.

P M Pitha, D L Slate, N B Raj, F H Ruddle.   

Abstract

The human fibroblast interferon gene beta 1 was mapped to human chromosome 9. Sequence homology with a beta 1 cDNA clone was detected in both genomic DNA and induced mRNA of human/mouse or human/hamster somatic cell hybrids containing human chromosome 9, but not in lines lacking this chromosome or those retaining a complex translocation involving chromosomes 9 and 11. Interferon mRNA that did not share sequence homology with the beta 1 cDNA clone was detected in lines containing human chromosomes 2 and 5 but lacking chromosome 9, suggesting the presence of other unlinked interferon sequences in the human genome.

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Year:  1982        PMID： 6180309      PMCID： PMC369826          DOI： 10.1128/mcb.2.5.564-570.1982

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  22 in total

1.  Interferon activity produced by translation of human interferon messenger RNA in cell-free ribosomal systems and in Xenopus oöcytes.

Authors:  F H Reynolds; E Premkumar; P M Pitha
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

Review 3.  Ph1-positive leukaemia, including chronic myelogenous leukaemia.

Authors:  J D Rowley
Journal:  Clin Haematol       Date:  1980-02

4.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

5.  Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Authors:  G M Wahl; M Stern; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

6.  Involvement of a gene on chromosome 9 in human fibroblast interferon production.

Authors:  A Meager; H Graves; D C Burke; D M Swallow
Journal:  Nature       Date:  1979-08-09       Impact factor: 49.962

7.  The somatic cell genetics of human interferon: assignment of human interferon loci to chromosomes 2 and 5.

Authors:  Y H Tan; R P Creagan; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1974-06       Impact factor: 11.205

8.  Somatic cell genetics of human interferon production in human-rodent cell hybrids.

Authors:  A Meager; H E Graves; J R Walker; D C Burke; D M Swallow; A Westerveld
Journal:  J Gen Virol       Date:  1979-11       Impact factor: 3.891

9.  Messenger RNA for myosin polypeptides: isolation from single myogenic cell cultures.

Authors:  R C Strohman; P S Moss; J Micou-Eastwood; D Spector; A Przybyla; B Paterson
Journal:  Cell       Date:  1977-02       Impact factor: 41.582

10.  Fibroblast interferon in man is coded by two loci on separate chromosomes.

Authors:  D L Slate; F H Ruddle
Journal:  Cell       Date:  1979-01       Impact factor: 41.582
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  7 in total

1.  Family of human alpha-interferon-like sequences.

Authors:  S I Feinstein; Y Mory; Y Chernajovsky; L Maroteaux; U Nir; V Lavie; M Revel
Journal:  Mol Cell Biol       Date:  1985-03       Impact factor: 4.272

2.  Two levels of regulation of beta-interferon gene expression in human cells.

Authors:  N B Raj; P M Pitha
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

3.  Characterization of a mouse interferon gene locus I. Isolation of a cluster of four alpha interferon genes.

Authors:  K A Kelley; P M Pitha
Journal:  Nucleic Acids Res       Date:  1985-02-11       Impact factor: 16.971

4.  Induction of human beta-interferon synthesis with poly(rI . rC) in mouse cells transfected with cloned cDNA plasmids.

Authors:  P M Pitha; D M Ciufo; M Kellum; N B Raj; G R Reyes; G S Hayward
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

5.  Linkage analysis of the murine interferon-alpha locus on chromosome 4.

Authors:  F Dandoy; K A Kelley; J DeMaeyer-Guignard; E DeMaeyer; P M Pitha
Journal:  J Exp Med       Date:  1984-07-01       Impact factor: 14.307

6.  Human immune interferon gene is located on chromosome 12.

Authors:  S L Naylor; A Y Sakaguchi; T B Shows; M L Law; D V Goeddel; P W Gray
Journal:  J Exp Med       Date:  1983-03-01       Impact factor: 14.307

7.  Multiple human beta interferon genes.

Authors:  A D Sagar; P B Sehgal; D L Slate; F H Ruddle
Journal:  J Exp Med       Date:  1982-09-01       Impact factor: 14.307
  7 in total

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