Literature DB >> 29298960

Simulation study of the second-generation MR-compatible SPECT system based on the inverted compound-eye gamma camera design.

Xiaochun Lai1, Ling-Jian Meng.   

Abstract

In this paper, we present simulation studies for the second-generation MRI compatible SPECT system, MRC-SPECT-II, based on an inverted compound eye (ICE) gamma camera concept. The MRC-SPECT-II system consists of a total of 1536 independent micro-pinhole-camera-elements (MCEs) distributed in a ring with an inner diameter of 6 cm. This system provides a FOV of 1 cm diameter and a peak geometrical efficiency of approximately 1.3% (the typical levels of 0.1%-0.01% found in modern pre-clinical SPECT instrumentations), while maintaining a sub-500 μm spatial resolution. Compared to the first-generation MRC-SPECT system (MRC-SPECT-I) (Cai 2014 Nucl. Instrum. Methods Phys. Res. A 734 147-51) developed in our lab, the MRC-SPECT-II system offers a similar resolution with dramatically improved sensitivity and greatly reduced physical dimension. The latter should allow the system to be placed inside most clinical and pre-clinical MRI scanners for high-performance simultaneous MRI and SPECT imaging.

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Year:  2018        PMID： 29298960      PMCID： PMC5880680          DOI： 10.1088/1361-6560/aaa4fb

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN： 0031-9155            Impact factor:   3.609


  23 in total

1.  Genome-wide atlas of gene expression in the adult mouse brain.

Authors:  Ed S Lein; Michael J Hawrylycz; Nancy Ao; Mikael Ayres; Amy Bensinger; Amy Bernard; Andrew F Boe; Mark S Boguski; Kevin S Brockway; Emi J Byrnes; Lin Chen; Li Chen; Tsuey-Ming Chen; Mei Chi Chin; Jimmy Chong; Brian E Crook; Aneta Czaplinska; Chinh N Dang; Suvro Datta; Nick R Dee; Aimee L Desaki; Tsega Desta; Ellen Diep; Tim A Dolbeare; Matthew J Donelan; Hong-Wei Dong; Jennifer G Dougherty; Ben J Duncan; Amanda J Ebbert; Gregor Eichele; Lili K Estin; Casey Faber; Benjamin A Facer; Rick Fields; Shanna R Fischer; Tim P Fliss; Cliff Frensley; Sabrina N Gates; Katie J Glattfelder; Kevin R Halverson; Matthew R Hart; John G Hohmann; Maureen P Howell; Darren P Jeung; Rebecca A Johnson; Patrick T Karr; Reena Kawal; Jolene M Kidney; Rachel H Knapik; Chihchau L Kuan; James H Lake; Annabel R Laramee; Kirk D Larsen; Christopher Lau; Tracy A Lemon; Agnes J Liang; Ying Liu; Lon T Luong; Jesse Michaels; Judith J Morgan; Rebecca J Morgan; Marty T Mortrud; Nerick F Mosqueda; Lydia L Ng; Randy Ng; Geralyn J Orta; Caroline C Overly; Tu H Pak; Sheana E Parry; Sayan D Pathak; Owen C Pearson; Ralph B Puchalski; Zackery L Riley; Hannah R Rockett; Stephen A Rowland; Joshua J Royall; Marcos J Ruiz; Nadia R Sarno; Katherine Schaffnit; Nadiya V Shapovalova; Taz Sivisay; Clifford R Slaughterbeck; Simon C Smith; Kimberly A Smith; Bryan I Smith; Andy J Sodt; Nick N Stewart; Kenda-Ruth Stumpf; Susan M Sunkin; Madhavi Sutram; Angelene Tam; Carey D Teemer; Christina Thaller; Carol L Thompson; Lee R Varnam; Axel Visel; Ray M Whitlock; Paul E Wohnoutka; Crissa K Wolkey; Victoria Y Wong; Matthew Wood; Murat B Yaylaoglu; Rob C Young; Brian L Youngstrom; Xu Feng Yuan; Bin Zhang; Theresa A Zwingman; Allan R Jones
Journal:  Nature       Date:  2006-12-06       Impact factor: 49.962

2.  A Vector Uniform Cramer-Rao Bound for SPECT System Design.

Authors:  Ling-Jian Meng; Nan Li
Journal:  IEEE Trans Nucl Sci       Date:  2009-02-10       Impact factor: 1.679

3.  Estimate interaction timing in a large volume HgI2 detector using cathode pulse waveforms.

Authors:  L J Meng; Z He
Journal:  Nucl Instrum Methods Phys Res A       Date:  2005-03-23       Impact factor: 1.455

4.  Rapid additive manufacturing of MR compatible multipinhole collimators with selective laser melting of tungsten powder.

Authors:  Karel Deprez; Stefaan Vandenberghe; Karen Van Audenhaege; Jonas Van Vaerenbergh; Roel Van Holen
Journal:  Med Phys       Date:  2013-01       Impact factor: 4.071

5.  Performance measurements of the Siemens mMR integrated whole-body PET/MR scanner.

Authors:  Gaspar Delso; Sebastian Fürst; Björn Jakoby; Ralf Ladebeck; Carl Ganter; Stephan G Nekolla; Markus Schwaiger; Sibylle I Ziegler
Journal:  J Nucl Med       Date:  2011-11-11       Impact factor: 10.057

6.  Hybrid Pixel-Waveform (HPWF) Enabled CdTe Detectors for Small Animal Gamma-Ray Imaging Applications.

Authors:  A Groll; K Kim; H Bhatia; J C Zhang; J H Wang; Z M Shen; L Cai; J Dutta; Q Li; L J Meng
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2016-11-01

7.  SPECT system optimization against a discrete parameter space.

Authors:  L J Meng; N Li
Journal:  Phys Med Biol       Date:  2013-04-15       Impact factor: 3.609

8.  Development of a high-resolution detection module for the INSERT SPECT/MRI system.

Authors:  Paolo Busca; Carlo Fiorini; Arslan D Butt; Michele Occhipinti; Riccardo Quaglia; Paolo Trigilio; Gabor Nemeth; Peter Major; Tamas Bukki; Kalman Nagy; Claudio Piemonte; Alessandro Ferri; Alberto Gola; Jan Rieger; Thoralf Niendorf
Journal:  EJNMMI Phys       Date:  2014-07

9.  Development of clinical simultaneous SPECT/MRI.

Authors:  Brian F Hutton; Michele Occhipinti; Andre Kuehne; Domokos Máthé; Noémi Kovács; Helmar Waiczies; Kjell Erlandsson; Debora Salvado; Marco Carminati; Giovanni L Montagnani; Susan C Short; Luisa Ottobrini; Pieter van Mullekom; Claudio Piemonte; Tamas Bukki; Zoltan Nyitrai; Zoltan Papp; Kalman Nagy; Thoralf Niendorf; Irene de Francesco; Carlo Fiorini
Journal:  Br J Radiol       Date:  2017-03-07       Impact factor: 3.039

10.  Preliminary evaluation of image quality in a new clinical ToF-PET/MR scanner.

Authors:  Gaspar Delso; Mehdi Khalighi; Marlena Hofbauer; Miguel Porto; Patrick Veit-Haibach; Gustav von Schulthess
Journal:  EJNMMI Phys       Date:  2014-07
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  2 in total

1.  System Modeling and Evaluation of a Prototype Inverted-Compound Eye Gamma Camera for the Second Generation MR Compatible SPECT.

Authors:  Xiaochun Lai; Elena M Zannoni; Jonathan George; Ling-Jian Meng
Journal:  Nucl Instrum Methods Phys Res A       Date:  2019-04-17       Impact factor: 1.455

2.  Design Study of an Ultrahigh Resolution Brain SPECT System Using a Synthetic Compound-Eye Camera Design With Micro-Slit and Micro-Ring Apertures.

Authors:  Elena Maria Zannoni; Can Yang; Ling-Jian Meng
Journal:  IEEE Trans Med Imaging       Date:  2021-11-30       Impact factor: 10.048
  2 in total

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