Literature DB >> 23298112

Rapid additive manufacturing of MR compatible multipinhole collimators with selective laser melting of tungsten powder.

Karel Deprez1, Stefaan Vandenberghe, Karen Van Audenhaege, Jonas Van Vaerenbergh, Roel Van Holen.   

Abstract

PURPOSE: The construction of complex collimators with a high number of oblique pinholes is very labor intensive, expensive or is sometimes impossible with the current available techniques (drilling, milling or electric discharge machining). All these techniques are subtractive: one starts from solid plates and the material at the position of the pinholes is removed. The authors used a novel technique for collimator construction, called metal additive manufacturing. This process starts with a solid piece of tungsten on which a first layer of tungsten powder is melted. Each subsequent layer is then melted on the previous layer. This melting is done by selective laser melting at the locations where the CAD design file defines solid material.
METHODS: A complex collimator with 20 loftholes with 500 μm diameter pinhole opening was designed and produced (16 mm thick and 70 × 52 mm(2) transverse size). The density was determined, the production accuracy was measured (GOM ATOS II Triple Scan, Nikon AZ100M microscope, Olympus IMT200 microscope). Point source measurements were done by mounting the collimator on a SPECT detector. Because there is increasing interest in dual-modality SPECT-MR imaging, the collimator was also positioned in a 7T MRI scanner (Bruker Pharmascan). A uniform phantom was acquired using T1, T2, and T2* sequences to check for artifacts or distortion of the phantom images due to the collimator presence. Additionally, three tungsten sample pieces (250, 500, and 750 μm thick) were produced. The density, attenuation (140 keV beam), and uniformity (GE eXplore Locus SP micro-CT) of these samples were measured.
RESULTS: The density of the collimator was equal to 17.31 ± 0.10 g∕cm(3) (89.92% of pure tungsten). The production accuracy ranges from -260 to +650 μm. The aperture positions have a mean deviation of 5 μm, the maximum deviation was 174 μm and the minimum deviation was -122 μm. The mean aperture diameter is 464 ± 19 μm. The calculated and measured sensitivity and resolution of point sources at different positions in the field-of-view agree well. The measured and expected attenuation of the three sample pieces are in a good agreement. There was no influence of the 7T magnetic field on the collimator (which is paramagnetic) and minimal distortion was noticed on the MR scan of the uniform phantom.
CONCLUSIONS: Additive manufacturing is a very promising technique for the production of complex multipinhole collimators and may also be used for producing other complex collimators. The cost of this technique is only related to the amount of powder needed and the time it takes to have the collimator built. The timeframe from design to collimator production is significantly reduced.

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Year:  2013        PMID: 23298112     DOI: 10.1118/1.4769122

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  6 in total

Review 1.  Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging.

Authors:  Karen Van Audenhaege; Roel Van Holen; Stefaan Vandenberghe; Christian Vanhove; Scott D Metzler; Stephen C Moore
Journal:  Med Phys       Date:  2015-08       Impact factor: 4.071

2.  Simulation study of the second-generation MR-compatible SPECT system based on the inverted compound-eye gamma camera design.

Authors:  Xiaochun Lai; Ling-Jian Meng
Journal:  Phys Med Biol       Date:  2018-02-12       Impact factor: 3.609

3.  System Modeling and Evaluation of a Prototype Inverted-Compound Eye Gamma Camera for the Second Generation MR Compatible SPECT.

Authors:  Xiaochun Lai; Elena M Zannoni; Jonathan George; Ling-Jian Meng
Journal:  Nucl Instrum Methods Phys Res A       Date:  2019-04-17       Impact factor: 1.455

4.  Integration of AdaptiSPECT, a small-animal adaptive SPECT imaging system.

Authors:  Cécile Chaix; Stephen Kovalsky; Matthew Kosmider; Harrison H Barrett; Lars R Furenlid
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2013-08-25

5.  Selective laser melting of high-performance pure tungsten: parameter design, densification behavior and mechanical properties.

Authors:  Chaolin Tan; Kesong Zhou; Wenyou Ma; Bonnie Attard; Panpan Zhang; Tongchun Kuang
Journal:  Sci Technol Adv Mater       Date:  2018-04-18       Impact factor: 8.090

6.  Development of clinical simultaneous SPECT/MRI.

Authors:  Brian F Hutton; Michele Occhipinti; Andre Kuehne; Domokos Máthé; Noémi Kovács; Helmar Waiczies; Kjell Erlandsson; Debora Salvado; Marco Carminati; Giovanni L Montagnani; Susan C Short; Luisa Ottobrini; Pieter van Mullekom; Claudio Piemonte; Tamas Bukki; Zoltan Nyitrai; Zoltan Papp; Kalman Nagy; Thoralf Niendorf; Irene de Francesco; Carlo Fiorini
Journal:  Br J Radiol       Date:  2017-03-07       Impact factor: 3.039

  6 in total

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