Literature DB >> 27487896

Technical Report: Evaluation of peripheral dose for flattening filter free photon beams.

E L Covington1, T A Ritter2, J M Moran1, A M Owrangi1, J I Prisciandaro1.   

Abstract

PURPOSE: To develop a comprehensive peripheral dose (PD) dataset for the two unflattened beams of nominal energy 6 and 10 MV for use in clinical care.
METHODS: Measurements were made in a 40 × 120 × 20 cm(3) (width × length × depth) stack of solid water using an ionization chamber at varying depths (dmax, 5, and 10 cm), field sizes (3 × 3 to 30 × 30 cm(2)), and distances from the field edge (5-40 cm). The effects of the multileaf collimator (MLC) and collimator rotation were also evaluated for a 10 × 10 cm(2) field. Using the same phantom geometry, the accuracy of the analytic anisotropic algorithm (AAA) and Acuros dose calculation algorithm was assessed and compared to the measured values.
RESULTS: The PDs for both the 6 flattening filter free (FFF) and 10 FFF photon beams were found to decrease with increasing distance from the radiation field edge and the decreasing field size. The measured PD was observed to be higher for the 6 FFF than for the 10 FFF for all field sizes and depths. The impact of collimator rotation was not found to be clinically significant when used in conjunction with MLCs. AAA and Acuros algorithms both underestimated the PD with average errors of -13.6% and -7.8%, respectively, for all field sizes and depths at distances of 5 and 10 cm from the field edge, but the average error was found to increase to nearly -69% at greater distances.
CONCLUSIONS: Given the known inaccuracies of peripheral dose calculations, this comprehensive dataset can be used to estimate the out-of-field dose to regions of interest such as organs at risk, electronic implantable devices, and a fetus. While the impact of collimator rotation was not found to significantly decrease PD when used in conjunction with MLCs, results are expected to be machine model and beam energy dependent. It is not recommended to use a treatment planning system to estimate PD due to the underestimation of the out-of-field dose and the inability to calculate dose at extended distances due to the limits of the dose calculation matrix.

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Year:  2016        PMID: 27487896      PMCID: PMC5148180          DOI: 10.1118/1.4958963

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  28 in total

1.  Peripheral dose from a linear accelerator equipped with multileaf collimation.

Authors:  R L Stern
Journal:  Med Phys       Date:  1999-04       Impact factor: 4.071

2.  Flattening filter free vs flattened beams for breast irradiation.

Authors:  Kees H Spruijt; Max Dahele; Johan P Cuijpers; Marloes Jeulink; Derek Rietveld; Ben J Slotman; Wilko F A R Verbakel
Journal:  Int J Radiat Oncol Biol Phys       Date:  2012-06-05       Impact factor: 7.038

3.  Out-of-field photon dose following removal of the flattening filter from a medical accelerator.

Authors:  Stephen F Kry; Oleg N Vassiliev; Radhe Mohan
Journal:  Phys Med Biol       Date:  2010-03-19       Impact factor: 3.609

4.  Commissioning of photon beams of a flattening filter-free linear accelerator and the accuracy of beam modeling using an anisotropic analytical algorithm.

Authors:  Jan Hrbacek; Stephanie Lang; Stephan Klöck
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-12-02       Impact factor: 7.038

5.  Properties of unflattened photon beams shaped by a multileaf collimator.

Authors:  Falk Pönisch; Uwe Titt; Oleg N Vassiliev; Stephen F Kry; Radhe Mohan
Journal:  Med Phys       Date:  2006-06       Impact factor: 4.071

6.  Monte Carlo study of in-field and out-of-field dose distributions from a linear accelerator operating with and without a flattening-filter.

Authors:  S S Almberg; J Frengen; T Lindmo
Journal:  Med Phys       Date:  2012-08       Impact factor: 4.071

7.  Dosimetric characteristics of 6 and 10MV unflattened photon beams.

Authors:  Gabriele Kragl; Sacha af Wetterstedt; Barbara Knäusl; Mårten Lind; Patrick McCavana; Tommy Knöös; Brendan McClean; Dietmar Georg
Journal:  Radiother Oncol       Date:  2009-07-09       Impact factor: 6.280

8.  A simple and generally applicable method to estimate the peripheral dose in radiation teletherapy with high energy x-rays or gamma radiation.

Authors:  P H Van der Giessen
Journal:  Int J Radiat Oncol Biol Phys       Date:  1996-07-15       Impact factor: 7.038

9.  Calculation and measurement of the dose at points outside the primary beam for photon energies of 6, 10, and 23 MV.

Authors:  P H van der Giessen
Journal:  Int J Radiat Oncol Biol Phys       Date:  1994-12-01       Impact factor: 7.038

10.  Peripheral dose from megavolt beams.

Authors:  B A Fraass; J van de Geijn
Journal:  Med Phys       Date:  1983 Nov-Dec       Impact factor: 4.071

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  6 in total

1.  Measurement and modeling of out-of-field doses from various advanced post-mastectomy radiotherapy techniques.

Authors:  Jihyung Yoon; David Heins; Xiaodong Zhao; Mary Sanders; Rui Zhang
Journal:  Phys Med Biol       Date:  2017-11-13       Impact factor: 3.609

2.  Second cancer risk after radiation therapy of ependymoma using the flattening filter free irradiation mode of a linear accelerator.

Authors:  Judit Alvarez Moret; Tina Obermeier; Fabian Pohl; Rainer Loeschel; Oliver Koelbl; Barbara Dobler
Journal:  J Appl Clin Med Phys       Date:  2018-08-19       Impact factor: 2.102

3.  Association between treatment-related lymphopenia and survival in glioblastoma patients following postoperative chemoradiotherapy.

Authors:  Roberto Mapelli; Chiara Julita; Sofia Paola Bianchi; Nicolò Gallina; Raffaella Lucchini; Martina Midulla; Flavia Puci; Jessica Saddi; Sara Trivellato; Denis Panizza; Elena De Ponti; Stefano Arcangeli
Journal:  Strahlenther Onkol       Date:  2021-10-06       Impact factor: 3.621

4.  Volumetric-modulated arc therapy and intensity-modulated radiation therapy treatment planning for prostate cancer with flattened beam and flattening filter free linear accelerators.

Authors:  Marius Treutwein; Matthias Hipp; Oliver Koelbl; Barbara Dobler
Journal:  J Appl Clin Med Phys       Date:  2017-08-30       Impact factor: 2.102

5.  CyberKnife® fixed cone and Iris™ defined small radiation fields: Assessment with a high-resolution solid-state detector array.

Authors:  Giordano Biasi; Marco Petasecca; Susanna Guatelli; Ebert A Martin; Garry Grogan; Benjamin Hug; Jonathan Lane; Vladimir Perevertaylo; Tomas Kron; Anatoly B Rosenfeld
Journal:  J Appl Clin Med Phys       Date:  2018-07-12       Impact factor: 2.102

6.  Out-of-field dose in stereotactic radiotherapy for paediatric patients.

Authors:  Lachlan Garrett; Nicholas Hardcastle; Adam Yeo; Peta Lonski; Rick Franich; Tomas Kron
Journal:  Phys Imaging Radiat Oncol       Date:  2021-06-04
  6 in total

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