Literature DB >> 23257200

Quenching correction for volumetric scintillation dosimetry of proton beams.

Daniel Robertson1, Dragan Mirkovic, Narayan Sahoo, Sam Beddar.   

Abstract

Volumetric scintillation dosimetry has the potential to provide fast, high-resolution, three-dimensional radiation dosimetry. However, scintillators exhibit a nonlinear response at the high linear energy transfer (LET) values characteristic of proton Bragg peaks. The purpose of this study was to develop a quenching correction method for volumetric scintillation dosimetry of proton beams. Scintillation light from a miniature liquid scintillator detector was measured along the central axis of a 161.6 MeV proton pencil beam. Three-dimensional dose and LET distributions were calculated for 85.6, 100.9, 144.9 and 161.6 MeV beams using a validated Monte Carlo model. LET values were also calculated using an analytical formula. A least-squares fit to the data established the empirical parameters of a quenching correction model. The light distribution in a tank of liquid scintillator was measured with a CCD camera at all four beam energies. The quenching model and LET data were used to correct the measured light distribution. The calculated and measured Bragg peak heights agreed within ±3% for all energies except 85.6 MeV, where the agreement was within ±10%. The quality of the quenching correction was poorer for sharp low-energy Bragg peaks because of blurring and detector size effects. The corrections performed using analytical LET values resulted in doses within 1% of those obtained using Monte Carlo LET values. The proposed method can correct for quenching with sufficient accuracy for dosimetric purposes. The required LET values may be computed effectively using Monte Carlo or analytical methods. Future detectors should improve blurring correction methods and optimize the pixel size to improve accuracy for low-energy Bragg peaks.

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Year:  2012        PMID: 23257200      PMCID: PMC3849813          DOI: 10.1088/0031-9155/58/2/261

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  14 in total

1.  New water equivalent liquid scintillation solutions for 3D dosimetry.

Authors:  A S Kirov; S Shrinivas; C Hurlbut; J F Dempsey; W R Binns; J L Poblete
Journal:  Med Phys       Date:  2000-05       Impact factor: 4.071

2.  Analytical linear energy transfer calculations for proton therapy.

Authors:  Jan J Wilkens; Uwe Oelfke
Journal:  Med Phys       Date:  2003-05       Impact factor: 4.071

3.  Three-dimensional LET calculations for treatment planning of proton therapy.

Authors:  Jan J Wilkens; Uwe Oelfke
Journal:  Z Med Phys       Date:  2004       Impact factor: 4.820

4.  Verification of proton range, position, and intensity in IMPT with a 3D liquid scintillator detector system.

Authors:  L Archambault; F Poenisch; N Sahoo; D Robertson; A Lee; M T Gillin; R Mohan; S Beddar
Journal:  Med Phys       Date:  2012-03       Impact factor: 4.071

5.  The three-dimensional scintillation dosimetry method: test for a 106Ru eye plaque applicator.

Authors:  A S Kirov; J Z Piao; N K Mathur; T R Miller; S Devic; S Trichter; M Zaider; C G Soares; T LoSasso
Journal:  Phys Med Biol       Date:  2005-06-22       Impact factor: 3.609

6.  Development of an easy-to-handle range measurement tool using a plastic scintillator for proton beam therapy.

Authors:  Yasuhiro Fukushima; Minoru Hamada; Teiji Nishio; Koichi Maruyama
Journal:  Phys Med Biol       Date:  2006-10-26       Impact factor: 3.609

7.  Transient noise characterization and filtration in CCD cameras exposed to stray radiation from a medical linear accelerator.

Authors:  Louis Archambault; Tina Marie Briere; Sam Beddar
Journal:  Med Phys       Date:  2008-10       Impact factor: 4.071

8.  Commissioning of the discrete spot scanning proton beam delivery system at the University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston.

Authors:  Michael T Gillin; Narayan Sahoo; Martin Bues; George Ciangaru; Gabriel Sawakuchi; Falk Poenisch; Bijan Arjomandy; Craig Martin; Uwe Titt; Kazumichi Suzuki; Alfred R Smith; X Ronald Zhu
Journal:  Med Phys       Date:  2010-01       Impact factor: 4.071

9.  Verification of patient-specific dose distributions in proton therapy using a commercial two-dimensional ion chamber array.

Authors:  Bijan Arjomandy; Narayan Sahoo; George Ciangaru; Ronald Zhu; Xiaofei Song; Michael Gillin
Journal:  Med Phys       Date:  2010-11       Impact factor: 4.071

10.  Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams.

Authors:  L L W Wang; L A Perles; L Archambault; N Sahoo; D Mirkovic; S Beddar
Journal:  Phys Med Biol       Date:  2012-11-06       Impact factor: 3.609

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  13 in total

1.  Ionization quenching correction for a 3D scintillator detector exposed to scanning proton beams.

Authors:  Fahed Alsanea; Chinmay Darne; Daniel Robertson; Sam Beddar
Journal:  Phys Med Biol       Date:  2020-04-06       Impact factor: 3.609

2.  Polyenergetic Data Acquisition Using a Video-Scintillator Detector for Scanned Proton Beams.

Authors:  John G Eley; Daniel R Strauss; Ulrich W Langner
Journal:  Int J Part Ther       Date:  2017-03-14

3.  Calculations and measurements of the scintillator-to-water stopping power ratio of liquid scintillators for use in proton radiotherapy.

Authors:  W Scott Ingram; Daniel Robertson; Sam Beddar
Journal:  Nucl Instrum Methods Phys Res A       Date:  2015-03-11       Impact factor: 1.455

4.  Optical artefact characterization and correction in volumetric scintillation dosimetry.

Authors:  Daniel Robertson; Cheukkai Hui; Louis Archambault; Radhe Mohan; Sam Beddar
Journal:  Phys Med Biol       Date:  2013-12-10       Impact factor: 3.609

5.  3D reconstruction of scintillation light emission from proton pencil beams using limited viewing angles-a simulation study.

Authors:  CheukKai Hui; Daniel Robertson; Sam Beddar
Journal:  Phys Med Biol       Date:  2014-07-23       Impact factor: 3.609

6.  Determination of the Range and Spread-Out Bragg Peak Width of Proton Beams Using a Large-Volume Liquid Scintillator.

Authors:  Thomas Henry; Daniel Robertson; François Therriault-Proulx; Sam Beddar
Journal:  Int J Part Ther       Date:  2017-09-26

Review 7.  Towards effective and efficient patient-specific quality assurance for spot scanning proton therapy.

Authors:  X Ronald Zhu; Yupeng Li; Dennis Mackin; Heng Li; Falk Poenisch; Andrew K Lee; Anita Mahajan; Steven J Frank; Michael T Gillin; Narayan Sahoo; Xiaodong Zhang
Journal:  Cancers (Basel)       Date:  2015-04-10       Impact factor: 6.639

8.  Quality assurance in proton beam therapy using a plastic scintillator and a commercially available digital camera.

Authors:  Mansour Almurayshid; Yusuf Helo; Andrzej Kacperek; Jennifer Griffiths; Jem Hebden; Adam Gibson
Journal:  J Appl Clin Med Phys       Date:  2017-07-29       Impact factor: 2.102

9.  Optical imaging of muons.

Authors:  Seiichi Yamamoto; Kazuhiko Ninomiya; Naritoshi Kawamura; Yoshiyuki Hirano
Journal:  Sci Rep       Date:  2020-11-26       Impact factor: 4.379

10.  Empirical quenching correction in radiochromic silicone-based three-dimensional dosimetry of spot-scanning proton therapy.

Authors:  Lia Barbosa Valdetaro; Ellen Marie Høye; Peter Sandegaard Skyt; Jørgen Breede Baltzer Petersen; Peter Balling; Ludvig Paul Muren
Journal:  Phys Imaging Radiat Oncol       Date:  2021-04-12
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