Literature DB >> 20175477

Commissioning of the discrete spot scanning proton beam delivery system at the University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston.

Michael T Gillin1, Narayan Sahoo, Martin Bues, George Ciangaru, Gabriel Sawakuchi, Falk Poenisch, Bijan Arjomandy, Craig Martin, Uwe Titt, Kazumichi Suzuki, Alfred R Smith, X Ronald Zhu.   

Abstract

PURPOSE: To describe a summary of the clinical commissioning of the discrete spot scanning proton beam at the Proton Therapy Center, Houston (PTC-H).
METHODS: Discrete spot scanning system is composed of a delivery system (Hitachi ProBeat), an electronic medical record (Mosaiq V 1.5), and a treatment planning system (TPS) (Eclipse V 8.1). Discrete proton pencil beams (spots) are used to deposit dose spot by spot and layer by layer for the proton distal ranges spanning from 4.0 to 30.6 g/cm2 and over a maximum scan area at the isocenter of 30 x 30 cm2. An arbitrarily chosen reference calibration condition has been selected to define the monitor units (MUs). Using radiochromic film and ion chambers, the authors have measured spot positions, the spot sizes in air, depth dose curves, and profiles for proton beams with various energies in water, and studied the linearity of the dose monitors. In addition to dosimetric measurements and TPS modeling, significant efforts were spent in testing information flow and recovery of the delivery system from treatment interruptions.
RESULTS: The main dose monitors have been adjusted such that a specific amount of charge is collected in the monitor chamber corresponding to a single MU, following the IAEA TRS 398 protocol under a specific reference condition. The dose monitor calibration method is based on the absolute dose per MU, which is equivalent to the absolute dose per particle, the approach used by other scanning beam institutions. The full width at half maximum for the spot size in air varies from approximately 1.2 cm for 221.8 MeV to 3.4 cm for 72.5 MeV. The measured versus requested 90% depth dose in water agrees to within 1 mm over ranges of 4.0-30.6 cm. The beam delivery interlocks perform as expected, guarantying the safe and accurate delivery of the planned dose.
CONCLUSIONS: The dosimetric parameters of the discrete spot scanning proton beam have been measured as part of the clinical commissioning program, and the machine is found to function in a safe manner, making it suitable for patient treatment.

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Year:  2010        PMID: 20175477     DOI: 10.1118/1.3259742

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  71 in total

1.  Verification of proton range, position, and intensity in IMPT with a 3D liquid scintillator detector system.

Authors:  L Archambault; F Poenisch; N Sahoo; D Robertson; A Lee; M T Gillin; R Mohan; S Beddar
Journal:  Med Phys       Date:  2012-03       Impact factor: 4.071

2.  An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle.

Authors:  Gabriel O Sawakuchi; Dragan Mirkovic; Luis A Perles; Narayan Sahoo; X Ron Zhu; George Ciangaru; Kazumichi Suzuki; Michael T Gillin; Radhe Mohan; Uwe Titt
Journal:  Med Phys       Date:  2010-09       Impact factor: 4.071

3.  Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code.

Authors:  Fada Guan; Christopher Peeler; Lawrence Bronk; Changran Geng; Reza Taleei; Sharmalee Randeniya; Shuaiping Ge; Dragan Mirkovic; David Grosshans; Radhe Mohan; Uwe Titt
Journal:  Med Phys       Date:  2015-11       Impact factor: 4.071

4.  Quality assurance evaluation of spot scanning beam proton therapy with an anthropomorphic prostate phantom.

Authors:  K Iqbal; M Gillin; P A Summers; S Dhanesar; K A Gifford; S A Buzdar
Journal:  Br J Radiol       Date:  2013-09-18       Impact factor: 3.039

5.  Fast range measurement of spot scanning proton beams using a volumetric liquid scintillator detector.

Authors:  CheukKai Hui; Daniel Robertson; Fahed Alsanea; Sam Beddar
Journal:  Biomed Phys Eng Express       Date:  2015-07-30

6.  Impact of range shifter material on proton pencil beam spot characteristics.

Authors:  Jiajian Shen; Wei Liu; Aman Anand; Joshua B Stoker; Xiaoning Ding; Mirek Fatyga; Michael G Herman; Martin Bues
Journal:  Med Phys       Date:  2015-03       Impact factor: 4.071

7.  Interpolation of tabulated proton Bragg peaks.

Authors:  Benjamin M Clasie; Jacob B Flanz; Hanne M Kooy
Journal:  Phys Med Biol       Date:  2012-10-17       Impact factor: 3.609

8.  Optical artefact characterization and correction in volumetric scintillation dosimetry.

Authors:  Daniel Robertson; Cheukkai Hui; Louis Archambault; Radhe Mohan; Sam Beddar
Journal:  Phys Med Biol       Date:  2013-12-10       Impact factor: 3.609

9.  Use of treatment log files in spot scanning proton therapy as part of patient-specific quality assurance.

Authors:  Heng Li; Narayan Sahoo; Falk Poenisch; Kazumichi Suzuki; Yupeng Li; Xiaoqiang Li; Xiaodong Zhang; Andrew K Lee; Michael T Gillin; X Ronald Zhu
Journal:  Med Phys       Date:  2013-02       Impact factor: 4.071

10.  Quenching correction for volumetric scintillation dosimetry of proton beams.

Authors:  Daniel Robertson; Dragan Mirkovic; Narayan Sahoo; Sam Beddar
Journal:  Phys Med Biol       Date:  2012-12-21       Impact factor: 3.609

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