Literature DB >> 23128412

Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams.

L L W Wang1, L A Perles, L Archambault, N Sahoo, D Mirkovic, S Beddar.   

Abstract

Plastic scintillation detectors (PSDs) have many advantages over other detectors in small field dosimetry due to their high spatial resolution, excellent water equivalence and instantaneous readout. However, in proton beams, the PSDs undergo a quenching effect which makes the signal level reduced significantly when the detector is close to the Bragg peak where the linear energy transfer (LET) for protons is very high. This study measures the quenching correction factor (QCF) for a PSD in clinical passive-scattering proton beams and investigates the feasibility of using PSDs in depth-dose measurements in proton beams. A polystyrene-based PSD (BCF-12, ϕ0.5 mm × 4 mm) was used to measure the depth-dose curves in a water phantom for monoenergetic unmodulated proton beams of nominal energies 100, 180 and 250 MeV. A Markus plane-parallel ion chamber was also used to get the dose distributions for the same proton beams. From these results, the QCF as a function of depth was derived for these proton beams. Next, the LET depth distributions for these proton beams were calculated by using the MCNPX Monte Carlo code, based on the experimentally validated nozzle models for these passive-scattering proton beams. Then the relationship between the QCF and the proton LET could be derived as an empirical formula. Finally, the obtained empirical formula was applied to the PSD measurements to get the corrected depth-dose curves and they were compared to the ion chamber measurements. A linear relationship between the QCF and LET, i.e. Birks' formula, was obtained for the proton beams studied. The result is in agreement with the literature. The PSD measurements after the quenching corrections agree with ion chamber measurements within 5%. PSDs are good dosimeters for proton beam measurement if the quenching effect is corrected appropriately.

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Year:  2012        PMID: 23128412      PMCID: PMC3849705          DOI: 10.1088/0031-9155/57/23/7767

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  15 in total

1.  Analytical linear energy transfer calculations for proton therapy.

Authors:  Jan J Wilkens; Uwe Oelfke
Journal:  Med Phys       Date:  2003-05       Impact factor: 4.071

2.  Dosimetric performance and array assessment of plastic scintillation detectors for stereotactic radiosurgery quality assurance.

Authors:  Jean-Christophe Gagnon; Dany Thériault; Mathieu Guillot; Louis Archambault; Sam Beddar; Luc Gingras; Luc Beaulieu
Journal:  Med Phys       Date:  2012-01       Impact factor: 4.071

3.  Development of an inorganic scintillating mixture for proton beam verification dosimetry.

Authors:  Sairos Safai; Shixiong Lin; Eros Pedroni
Journal:  Phys Med Biol       Date:  2004-10-07       Impact factor: 3.609

4.  Measurement accuracy and cerenkov removal for high performance, high spatial resolution scintillation dosimetry.

Authors:  Louis Archambault; A Sam Beddar; Luc Gingras; René Roy; Luc Beaulieu
Journal:  Med Phys       Date:  2006-01       Impact factor: 4.071

5.  Monte Carlo calculated stopping-power ratios, water/air, for clinical proton dosimetry (50-250 MeV).

Authors:  J Medin; P Andreo
Journal:  Phys Med Biol       Date:  1997-01       Impact factor: 3.609

6.  A comparative study of small field total scatter factors and dose profiles using plastic scintillation detectors and other stereotactic dosimeters: the case of the CyberKnife.

Authors:  Jonathan Morin; Dominic Beliveau-Nadeau; Eunah Chung; Jan Seuntjens; Dany Theriault; Louis Archambault; Sam Beddar; Luc Beaulieu
Journal:  Med Phys       Date:  2013-01       Impact factor: 4.071

7.  Spectral discrimination of Cerenkov radiation in scintillating dosimeters.

Authors:  A M Frelin; J M Fontbonne; G Ban; J Colin; M Labalme; A Batalla; A Isambert; A Vela; T Leroux
Journal:  Med Phys       Date:  2005-09       Impact factor: 4.071

8.  Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: II. Properties and measurements.

Authors:  A S Beddar; T R Mackie; F H Attix
Journal:  Phys Med Biol       Date:  1992-10       Impact factor: 3.609

9.  Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: I. Physical characteristics and theoretical consideration.

Authors:  A S Beddar; T R Mackie; F H Attix
Journal:  Phys Med Biol       Date:  1992-10       Impact factor: 3.609

Review 10.  Current developments in proton therapy: a review.

Authors:  D E Bonnett
Journal:  Phys Med Biol       Date:  1993-10       Impact factor: 3.609

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  9 in total

1.  Ionization quenching correction for a 3D scintillator detector exposed to scanning proton beams.

Authors:  Fahed Alsanea; Chinmay Darne; Daniel Robertson; Sam Beddar
Journal:  Phys Med Biol       Date:  2020-04-06       Impact factor: 3.609

2.  A Millimeter-scale Single Charged Particle Dosimeter for Cancer Radiotherapy.

Authors:  Kyoungtae Lee; Jessica Scholey; Eric B Norman; Inder K Daftari; Kavita K Mishra; Bruce A Faddegon; Michel M Maharbiz; Mekhail Anwar
Journal:  IEEE J Solid-State Circuits       Date:  2020-09-23       Impact factor: 5.013

3.  Polyethylene Naphthalate Scintillator: A Novel Detector for the Dosimetry of Radioactive Ophthalmic Applicators.

Authors:  Dirk Flühs; Andrea Flühs; Melanie Ebenau; Marion Eichmann
Journal:  Ocul Oncol Pathol       Date:  2015-06-06

4.  Passively scattered proton beam entrance dosimetry with a plastic scintillation detector.

Authors:  Landon Wootton; Charles Holmes; Narayan Sahoo; Sam Beddar
Journal:  Phys Med Biol       Date:  2015-01-15       Impact factor: 3.609

5.  Quenching correction for volumetric scintillation dosimetry of proton beams.

Authors:  Daniel Robertson; Dragan Mirkovic; Narayan Sahoo; Sam Beddar
Journal:  Phys Med Biol       Date:  2012-12-21       Impact factor: 3.609

6.  Quality assurance in proton beam therapy using a plastic scintillator and a commercially available digital camera.

Authors:  Mansour Almurayshid; Yusuf Helo; Andrzej Kacperek; Jennifer Griffiths; Jem Hebden; Adam Gibson
Journal:  J Appl Clin Med Phys       Date:  2017-07-29       Impact factor: 2.102

7.  Ultra-high dose rate dosimetry: Challenges and opportunities for FLASH radiation therapy.

Authors:  Francesco Romano; Claude Bailat; Patrik Gonçalves Jorge; Michael Lloyd Franz Lerch; Arash Darafsheh
Journal:  Med Phys       Date:  2022-05-07       Impact factor: 4.506

8.  Sensitivity analysis of Monte Carlo model of a gantry-mounted passively scattered proton system.

Authors:  Milad Baradaran-Ghahfarokhi; Francisco Reynoso; Michael T Prusator; Baozhou Sun; Tianyu Zhao
Journal:  J Appl Clin Med Phys       Date:  2020-01-03       Impact factor: 2.102

9.  Characterization of a Low-Cost Plastic Fiber Array Detector for Proton Beam Dosimetry.

Authors:  Cigdem Ozkan Loch; Michael Alexander Eichenberger; Michele Togno; Simon Pascal Zinsli; Martina Egloff; Angela Papa; Rasmus Ischebeck; Antony John Lomax; Peter Peier; Sairos Safai
Journal:  Sensors (Basel)       Date:  2020-10-09       Impact factor: 3.576

  9 in total

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