Literature DB >> 22382803

Tilting at windmills no longer: a data-driven discussion of DTC DNA ancestry tests.

Jennifer K Wagner1, Jill D Cooper, Rene Sterling, Charmaine D Royal.   

Abstract

PURPOSE: Discussions about direct-to-consumer (DTC) DNA ancestry tests have to date been based primarily on conjectures, speculation, and anecdotes, despite the industry being more than a decade old. Representative, empirical data on consumer characteristics; motivations and expectations for testing; intended uses for the information; understanding of results; and behavioral and psychological reactions to the tests are absent. Although the 2010 American Society of Human Genetics white paper clarifies the number and some general characteristics of companies marketing and selling DNA ancestry tests, additional data about the industry's practices have been unavailable.
METHODS: To promote a data-driven discussion of the DNA ancestry testing industry, we conducted a systematic investigation to identify companies selling DNA ancestry tests and conducted an empirical study of the industry's practices using data collected from each company's website.
RESULTS: Here, we present a wealth of data, including an updated directory of companies, marketing slogans, product types and names, range of prices, diversity of reporting and representing results, noted benefits and limitations of testing, and a host of website practices.
CONCLUSION: The tremendous diversity of tests, information, and practices of companies in the DNA ancestry sector should be considered when policies for best practice guidelines or regulatory oversight are being developed.

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Year:  2012        PMID: 22382803      PMCID: PMC8339991          DOI: 10.1038/gim.2011.77

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  24 in total

1.  Direct-to-consumer sales of genetic services on the Internet.

Authors:  Sarah E Gollust; Benjamin S Wilfond; Sara Chandros Hull
Journal:  Genet Med       Date:  2003 Jul-Aug       Impact factor: 8.822

2.  Inferring genetic ancestry: opportunities, challenges, and implications.

Authors:  Charmaine D Royal; John Novembre; Stephanie M Fullerton; David B Goldstein; Jeffrey C Long; Michael J Bamshad; Andrew G Clark
Journal:  Am J Hum Genet       Date:  2010-05-14       Impact factor: 11.025

3.  Interpreting the implications of DNA ancestry tests.

Authors:  Jennifer K Wagner
Journal:  Perspect Biol Med       Date:  2010       Impact factor: 1.416

4.  Genetics. The science and business of genetic ancestry testing.

Authors:  Deborah A Bolnick; Duana Fullwiley; Troy Duster; Richard S Cooper; Joan H Fujimura; Jonathan Kahn; Jay S Kaufman; Jonathan Marks; Ann Morning; Alondra Nelson; Pilar Ossorio; Jenny Reardon; Susan M Reverby; Kimberly TallBear
Journal:  Science       Date:  2007-10-19       Impact factor: 47.728

5.  Narratives of race and indigeneity in the Genographic Project.

Authors:  Kim TallBear
Journal:  J Law Med Ethics       Date:  2007       Impact factor: 1.718

Review 6.  Genomics and identity: the bioinformatisation of human life.

Authors:  Hub Zwart
Journal:  Med Health Care Philos       Date:  2009-02-26

7.  Genetics. The illusive gold standard in genetic ancestry testing.

Authors:  Sandra Soo-Jin Lee; Sandra Soo-Jin Lee; Deborah A Bolnick; Troy Duster; Pilar Ossorio; Kimberly Tallbear
Journal:  Science       Date:  2009-07-03       Impact factor: 47.728

8.  Attitudes on DNA ancestry tests.

Authors:  Jennifer K Wagner; Kenneth M Weiss
Journal:  Hum Genet       Date:  2011-06-23       Impact factor: 4.132

9.  The biologistical construction of race: 'admixture' technology and the new genetic medicine.

Authors:  Duana Fullwiley
Journal:  Soc Stud Sci       Date:  2008-10       Impact factor: 3.885

10.  Non-Darwinian estimation: my ancestors, my genes' ancestors.

Authors:  Kenneth M Weiss; Jeffrey C Long
Journal:  Genome Res       Date:  2009-05       Impact factor: 9.043

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  15 in total

1.  Attitudes on DNA ancestry tests.

Authors:  Jennifer K Wagner; Kenneth M Weiss
Journal:  Hum Genet       Date:  2011-06-23       Impact factor: 4.132

2.  Estimates of continental ancestry vary widely among individuals with the same mtDNA haplogroup.

Authors:  Leslie S Emery; Kevin M Magnaye; Abigail W Bigham; Joshua M Akey; Michael J Bamshad
Journal:  Am J Hum Genet       Date:  2015-01-22       Impact factor: 11.025

Review 3.  The Y chromosome as the most popular marker in genetic genealogy benefits interdisciplinary research.

Authors:  Francesc Calafell; Maarten H D Larmuseau
Journal:  Hum Genet       Date:  2016-11-05       Impact factor: 4.132

4.  Impacts of personal DNA ancestry testing.

Authors:  Caryn Kseniya Rubanovich; Riley Taitingfong; Cynthia Triplett; Ondrej Libiger; Nicholas J Schork; Jennifer K Wagner; Cinnamon S Bloss
Journal:  J Community Genet       Date:  2020-08-13

5.  Direct-to-Consumer Genetic Testing and Personal Genomics Services: A Review of Recent Empirical Studies.

Authors:  J Scott Roberts; Jenny Ostergren
Journal:  Curr Genet Med Rep       Date:  2013-09

6.  "Bridge to the Literature"? Third-Party Genetic Interpretation Tools and the Views of Tool Developers.

Authors:  Sarah C Nelson; Stephanie M Fullerton
Journal:  J Genet Couns       Date:  2018-02-07       Impact factor: 2.537

7.  Consumer (dis-)interest in Genetic Ancestry Testing: The roles of race, immigration, and ancestral certainty.

Authors:  Adam L Horowitz; Aliya Saperstein; Jasmine Little; Martin Maiers; Jill A Hollenbach
Journal:  New Genet Soc       Date:  2019-01-20

8.  Barriers and Strategies Related to Qualitative Research on Genetic Ancestry Testing in Indigenous Communities.

Authors:  Jessica W Blanchard; Gloria Tallbull; Chantelle Wolpert; Jill Powell; Morris W Foster; Charmaine Royal
Journal:  J Empir Res Hum Res Ethics       Date:  2017-04-23       Impact factor: 1.742

9.  Public reactions to direct-to-consumer genetic health tests: A comparison across the US, UK, Japan and Australia.

Authors:  Jan Charbonneau; Dianne Nicol; Don Chalmers; Kazuto Kato; Natsuko Yamamoto; Jarrod Walshe; Christine Critchley
Journal:  Eur J Hum Genet       Date:  2019-10-23       Impact factor: 5.351

10.  Field of genes: an investigation of sports-related genetic testing.

Authors:  Jennifer K Wagner; Charmaine D Royal
Journal:  J Pers Med       Date:  2012-09-12
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