Literature DB >> 21776799

Variations in photon energy spectra of a 6 MV beam and their impact on TLD response.

Sarah B Scarboro1, David S Followill, Rebecca M Howell, Stephen F Kry.   

Abstract

PURPOSE: Measurement of the absorbed dose from radiotherapy beams is an essential component of providing safe and reproducible treatment. For an energy-dependent dosimeter such as thermoluminescent dosimeters (TLDs), it is generally assumed that the energy spectrum is constant throughout the treatment field and is unperturbed by field size, depth, field modulation, or heterogeneities. However, this does not reflect reality and introduces error into clinical dose measurements. The purpose of this study was to evaluate the variability in the energy spectrum of a Varian 6 MV beam and to evaluate the impact of these variations in photon energy spectra on the response of a common energy-dependent dosimeter, TLD.
METHODS: Using Monte Carlo methods, we calculated variations in the photon energy spectra of a 6 MV beam as a result of variations of treatment parameters, including field size, measurement location, the presence of heterogeneities, and field modulation. The impact of these spectral variations on the response of the TLD is largely based on increased photoelectric effect in the dosimeter, and this impact was calculated using Burlin cavity theory. Measurements of the energy response were also made to determine the additional energy response due to all intrinsic and secondary effects.
RESULTS: For most in-field measurements, regardless of treatment parameter, the dosimeter response was not significantly affected by the spectral variations (<1% effect). For measurement points outside of the treatment field, where the spectrum is softer, the TLD over-responded by up to 12% due to an increased probability of photoelectric effect in the TLD material as well as inherent ionization density effects that play a role at low photon energies.
CONCLUSIONS: It is generally acceptable to ignore the impact of variations in the photon spectrum on the measured dose for locations within the treatment field. However, outside the treatment field, the spectra are much softer, and a correction factor is generally appropriate. The results of this work have determined values for this factor, which range from 0.88 to 0.99 depending on the specific irradiation conditions.

Mesh:

Year:  2011        PMID: 21776799      PMCID: PMC3107829          DOI: 10.1118/1.3575419

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  14 in total

1.  Energy spectra, angular spread, fluence profiles and dose distributions of 6 and 18 MV photon beams: results of monte carlo simulations for a varian 2100EX accelerator.

Authors:  George X Ding
Journal:  Phys Med Biol       Date:  2002-04-07       Impact factor: 3.609

2.  The response of lif thermoluminescence dosemeters to photon beams in the energy range from 30 kV x rays to 60Co gamma rays.

Authors:  S D Davis; C K Ross; P N Mobit; L Van der Zwan; W J Chase; K R Shortt
Journal:  Radiat Prot Dosimetry       Date:  2003       Impact factor: 0.972

3.  An investigation of energy spectrum and lineal energy variations in mega-voltage photon beams used for radiotherapy.

Authors:  H H Liu; F Verhaegen
Journal:  Radiat Prot Dosimetry       Date:  2002       Impact factor: 0.972

4.  Uncertainty analysis of absorbed dose calculations from thermoluminescence dosimeters.

Authors:  T H Kirby; W F Hanson; D A Johnston
Journal:  Med Phys       Date:  1992 Nov-Dec       Impact factor: 4.071

5.  Consistency of absorbed dose to water measurements using 21 ion-chamber models following the AAPM TG51 and TG21 calibration protocols.

Authors:  Ramesh C Tailor; William F Hanson; Nathan Wells; Geoffrey S Ibbott
Journal:  Med Phys       Date:  2006-06       Impact factor: 4.071

6.  A Monte Carlo model for calculating out-of-field dose from a varian 6 MV beam.

Authors:  Stephen F Kry; Uwe Titt; Falk Pönisch; David Followill; Oleg N Vassiliev; R Allen White; Radhe Mohan; Mohammad Salehpour
Journal:  Med Phys       Date:  2006-11       Impact factor: 4.071

7.  Variations in energy spectra and water-to-material stopping-power ratios in three-dimensional conformal and intensity-modulated photon fields.

Authors:  Si Young Jang; H Helen Liu; Radhe Mohan; Jeffrey V Siebers
Journal:  Med Phys       Date:  2007-04       Impact factor: 4.071

8.  LiF:Mg,Ti TLD response as a function of photon energy for moderately filtered x-ray spectra in the range of 20-250 kVp relative to 60Co.

Authors:  A A Nunn; S D Davis; J A Micka; L A DeWerd
Journal:  Med Phys       Date:  2008-05       Impact factor: 4.071

9.  Measurements of dose from secondary radiation outside a treatment field.

Authors:  K R Kase; G K Svensson; A B Wolbarst; M A Marks
Journal:  Int J Radiat Oncol Biol Phys       Date:  1983-08       Impact factor: 7.038

10.  A protocol for the determination of absorbed dose from high-energy photon and electron beams.

Authors: 
Journal:  Med Phys       Date:  1983 Nov-Dec       Impact factor: 4.071

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  18 in total

1.  The effect of energy spectrum change on DNA damage in and out of field in 10-MV clinical photon beams.

Authors:  A O Ezzati; Y Xiao; M Sohrabpour; M T Studenski
Journal:  Med Biol Eng Comput       Date:  2014-10-29       Impact factor: 2.602

2.  Measurement and modeling of out-of-field doses from various advanced post-mastectomy radiotherapy techniques.

Authors:  Jihyung Yoon; David Heins; Xiaodong Zhao; Mary Sanders; Rui Zhang
Journal:  Phys Med Biol       Date:  2017-11-13       Impact factor: 3.609

3.  Institutional patient-specific IMRT QA does not predict unacceptable plan delivery.

Authors:  Stephen F Kry; Andrea Molineu; James R Kerns; Austin M Faught; Jessie Y Huang; Kiley B Pulliam; Jackie Tonigan; Paola Alvarez; Francesco Stingo; David S Followill
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-10-21       Impact factor: 7.038

4.  Characterisation of energy response of Al(2)O(3):C optically stimulated luminescent dosemeters (OSLDs) using cavity theory.

Authors:  S B Scarboro; S F Kry
Journal:  Radiat Prot Dosimetry       Date:  2012-05-31       Impact factor: 0.972

5.  Analytical model for out-of-field dose in photon craniospinal irradiation.

Authors:  Phillip J Taddei; Wassim Jalbout; Rebecca M Howell; Nabil Khater; Fady Geara; Kenneth Homann; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2013-10-08       Impact factor: 3.609

6.  Technical Note: A Monte Carlo study of magnetic-field-induced radiation dose effects in mice.

Authors:  Ashley E Rubinstein; Zhongxing Liao; Adam D Melancon; Michele Guindani; David S Followill; Ramesh C Tailor; John D Hazle; Laurence E Court
Journal:  Med Phys       Date:  2015-09       Impact factor: 4.071

7.  Performance of KCl:Eu2+ storage phosphor dosimeters for low-dose measurements.

Authors:  H Harold Li; Zhiyan Xiao; Rachael Hansel; Nels Knutson; Deshan Yang
Journal:  Phys Med Biol       Date:  2013-06-05       Impact factor: 3.609

8.  Average stopping powers for electron and photon sources for radiobiological modeling and microdosimetric applications.

Authors:  Oleg N Vassiliev; Stephen F Kry; David R Grosshans; Radhe Mohan
Journal:  Phys Med Biol       Date:  2018-03-02       Impact factor: 3.609

9.  Energy spectrum and dose enhancement due to the depth of the Lipiodol position using flattened and unflattened beams.

Authors:  Daisuke Kawahara; Shuichi Ozawa; Akito Saito; Tomoki Kimura; Tatsuhiko Suzuki; Masato Tsuneda; Sodai Tanaka; Kazunari Hioki; Takeo Nakashima; Yoshimi Ohno; Yuji Murakami; Yasushi Nagata
Journal:  Rep Pract Oncol Radiother       Date:  2018-01-12

10.  Future directions on low-energy radiation dosimetry.

Authors:  G Massillon-Jl
Journal:  Sci Rep       Date:  2021-05-19       Impact factor: 4.379

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