Literature DB >> 21358048

JBluIce-EPICS control system for macromolecular crystallography.

Sergey Stepanov1, Oleg Makarov, Mark Hilgart, Sudhir Babu Pothineni, Alex Urakhchin, Satish Devarapalli, Derek Yoder, Michael Becker, Craig Ogata, Ruslan Sanishvili, Nagarajan Venugopalan, Janet L Smith, Robert F Fischetti.   

Abstract

The trio of macromolecular crystallography beamlines constructed by the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA-CAT) in Sector 23 of the Advanced Photon Source (APS) have been in growing demand owing to their outstanding beam quality and capacity to measure data from crystals of only a few micrometres in size. To take full advantage of the state-of-the-art mechanical and optical design of these beamlines, a significant effort has been devoted to designing fast, convenient, intuitive and robust beamline controls that could easily accommodate new beamline developments. The GM/CA-CAT beamline controls are based on the power of EPICS for distributed hardware control, the rich Java graphical user interface of Eclipse RCP and the task-oriented philosophy as well as the look and feel of the successful SSRL BluIce graphical user interface for crystallography. These beamline controls feature a minimum number of software layers, the wide use of plug-ins that can be written in any language and unified motion controls that allow on-the-fly scanning and optimization of any beamline component. This paper describes the ways in which BluIce was combined with EPICS and converted into the Java-based JBluIce, discusses the solutions aimed at streamlining and speeding up operations and gives an overview of the tools that are provided by this new open-source control system for facilitating crystallographic experiments, especially in the field of microcrystallography.

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Year:  2011        PMID: 21358048      PMCID: PMC3046456          DOI: 10.1107/S0907444910053916

Source DB:  PubMed          Journal:  Acta Crystallogr D Biol Crystallogr        ISSN: 0907-4449


  17 in total

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