Literature DB >> 21335649

Study of a high-resolution, 3D positioning cadmium zinc telluride detector for PET.

Y Gu1, J L Matteson, R T Skelton, A C Deal, E A Stephan, F Duttweiler, T M Gasaway, C S Levin.   

Abstract

This paper investigates the performance of 1 mm resolution cadmium zinc telluride (CZT) detectors for positron emission tomography (PET) capable of positioning the 3D coordinates of individual 511 keV photon interactions. The detectors comprise 40 mm × 40 mm × 5 mm monolithic CZT crystals that employ a novel cross-strip readout with interspersed steering electrodes to obtain high spatial and energy resolution. The study found a single anode FWHM energy resolution of 3.06 ± 0.39% at 511 keV throughout most of the detector volume. Improved resolution is expected with properly shielded front-end electronics. Measurements made using a collimated beam established the efficacy of the steering electrodes in facilitating enhanced charge collection across anodes, as well as a spatial resolution of 0.44 ± 0.07 mm in the direction orthogonal to the electrode planes. Finally, measurements based on coincidence electronic collimation yielded a point spread function with 0.78 ± 0.10 mm FWHM, demonstrating 1 mm spatial resolution capability transverse to the anodes-as expected from the 1 mm anode pitch. These findings indicate that the CZT-based detector concept has excellent performance and shows great promise for a high-resolution PET system.

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Year:  2011        PMID: 21335649      PMCID: PMC3274175          DOI: 10.1088/0031-9155/56/6/004

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  7 in total

1.  Performance evaluation of the 16-module quad-HIDAC small animal PET camera.

Authors:  John Missimer; Zoltan Madi; Michael Honer; Claudia Keller; August Schubiger; Simon-Mensah Ametamey
Journal:  Phys Med Biol       Date:  2004-05-21       Impact factor: 3.609

2.  Charge transport in arrays of semiconductor gamma-ray detectors.

Authors: 
Journal:  Phys Rev Lett       Date:  1995-07-03       Impact factor: 9.161

3.  Effects of multiple-interaction photon events in a high-resolution PET system that uses 3-D positioning detectors.

Authors:  Yi Gu; Guillem Pratx; Frances W Y Lau; Craig S Levin
Journal:  Med Phys       Date:  2010-10       Impact factor: 4.071

4.  Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging.

Authors:  Yongfeng Yang; Yuan-Chuan Tai; Stefan Siegel; Danny F Newport; Bing Bai; Quanzheng Li; Richard M Leahy; Simon R Cherry
Journal:  Phys Med Biol       Date:  2004-06-21       Impact factor: 3.609

5.  Effects of system geometry and other physical factors on photon sensitivity of high-resolution positron emission tomography.

Authors:  F Habte; A M K Foudray; P D Olcott; C S Levin
Journal:  Phys Med Biol       Date:  2007-05-29       Impact factor: 3.609

6.  Bayesian reconstruction of photon interaction sequences for high-resolution PET detectors.

Authors:  Guillem Pratx; Craig S Levin
Journal:  Phys Med Biol       Date:  2009-08-04       Impact factor: 3.609

7.  Impact of high energy resolution detectors on the performance of a PET system dedicated to breast cancer imaging.

Authors:  Craig S Levin; Angela M K Foudray; Frezghi Habte
Journal:  Phys Med       Date:  2006       Impact factor: 2.685

  7 in total
  29 in total

Review 1.  Promising new photon detection concepts for high-resolution clinical and preclinical PET.

Authors:  Craig S Levin
Journal:  J Nucl Med       Date:  2012-02       Impact factor: 10.057

2.  Attenuation correction in emission tomography using the emission data--A review.

Authors:  Yannick Berker; Yusheng Li
Journal:  Med Phys       Date:  2016-02       Impact factor: 4.071

Review 3.  Innovations in Instrumentation for Positron Emission Tomography.

Authors:  Eric Berg; Simon R Cherry
Journal:  Semin Nucl Med       Date:  2018-03-12       Impact factor: 4.446

4.  Side readout of long scintillation crystal elements with digital SiPM for TOF-DOI PET.

Authors:  Jung Yeol Yeom; Ruud Vinke; Craig S Levin
Journal:  Med Phys       Date:  2014-12       Impact factor: 4.071

5.  Effect of CZT system characteristics on Compton scatter event recovery.

Authors:  Sheng Yang; Mohan Li; Michael Reed; James Hugg; Henry Chen; Shiva Abbaszadeh
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2019-05-06

6.  Online detector response calculations for high-resolution PET image reconstruction.

Authors:  Guillem Pratx; Craig Levin
Journal:  Phys Med Biol       Date:  2011-06-15       Impact factor: 3.609

7.  A DOI Detector With Crystal Scatter Identification Capability for High Sensitivity and High Spatial Resolution PET Imaging.

Authors:  Z Gu; D L Prout; R W Silverman; H Herman; A Dooraghi; A F Chatziioannou
Journal:  IEEE Trans Nucl Sci       Date:  2015-06       Impact factor: 1.679

8.  Hybrid Pixel-Waveform (HPWF) Enabled CdTe Detectors for Small Animal Gamma-Ray Imaging Applications.

Authors:  A Groll; K Kim; H Bhatia; J C Zhang; J H Wang; Z M Shen; L Cai; J Dutta; Q Li; L J Meng
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2016-11-01

9.  Segmental and global left ventricular function assessment using gated SPECT with a semiconductor Cadmium Zinc Telluride (CZT) camera: phantom study and clinical validation vs cardiac magnetic resonance.

Authors:  Alban Bailliez; Tanguy Blaire; Frédéric Mouquet; R Legghe; B Etienne; Damien Legallois; Denis Agostini; Alain Manrique
Journal:  J Nucl Cardiol       Date:  2014-05-09       Impact factor: 5.952

10.  Investigation of the limitations of the highly pixilated CdZnTe detector for PET applications.

Authors:  Sergey Komarov; Yongzhi Yin; Heyu Wu; Jie Wen; Henric Krawczynski; Ling-Jian Meng; Yuan-Chuan Tai
Journal:  Phys Med Biol       Date:  2012-10-18       Impact factor: 3.609

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