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Literature DB >> 21081831

Analog signal multiplexing for PSAPD-based PET detectors: simulation and experimental validation.

Frances W Y Lau¹, Arne Vandenbroucke, Paul D Reynolds, Peter D Olcott, Mark A Horowitz, Craig S Levin.

Abstract

A 1 mm(3) resolution clinical positron emission tomography (PET) system employing 4608 position-sensitive avalanche photodiodes (PSAPDs) is under development. This paper describes a detector multiplexing technique that simplifies the readout electronics and reduces the density of the circuit board design. The multiplexing scheme was validated using a simulation framework that models the PSAPDs and front-end multiplexing circuits to predict the signal-to-noise ratio and flood histogram performance. Two independent experimental setups measured the energy resolution, time resolution, crystal identification ability and count rate both with and without multiplexing. With multiplexing, there was no significant degradation in energy resolution, time resolution and count rate. There was a relative 6.9 ± 1.0% and 9.4 ± 1.0% degradation in the figure of merit that characterizes the crystal identification ability observed in the measured and simulated ceramic-mounted PSAPD module flood histograms, respectively.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 21081831 PMCID： PMC3691840 DOI： 10.1088/0031-9155/55/23/001

Source DB: PubMed Journal: Phys Med Biol ISSN： 0031-9155 Impact factor: 3.609

13 in total

1. Effects of multiple-interaction photon events in a high-resolution PET system that uses 3-D positioning detectors.

Authors: Yi Gu; Guillem Pratx; Frances W Y Lau; Craig S Levin
Journal: Med Phys Date: 2010-10 Impact factor: 4.071

2. Performance measurements of a depth-encoding PET detector module based on position-sensitive avalanche photodiode read-out.

Authors: P A Dokhale; R W Silverman; K S Shah; R Grazioso; R Farrell; J Glodo; M A McClish; G Entine; V H Tran; S R Cherry
Journal: Phys Med Biol Date: 2004-09-21 Impact factor: 3.609

3. A new timing model for calculating the intrinsic timing resolution of a scintillator detector.

Authors: Yiping Shao
Journal: Phys Med Biol Date: 2007-01-25 Impact factor: 3.609

4. Convex optimization of coincidence time resolution for a high-resolution PET system.

Authors: Paul D Reynolds; Peter D Olcott; Guillem Pratx; Frances W Y Lau; Craig S Levin
Journal: IEEE Trans Med Imaging Date: 2010-09-27 Impact factor: 10.048

5. The positron emission mammography/tomography breast imaging and biopsy system (PEM/PET): design, construction and phantom-based measurements.

Authors: Raymond R Raylman; Stan Majewski; Mark F Smith; James Proffitt; William Hammond; Amarnath Srinivasan; John McKisson; Vladimir Popov; Andrew Weisenberger; Clifford O Judy; Brian Kross; Srikanth Ramasubramanian; Larry E Banta; Paul E Kinahan; Kyle Champley
Journal: Phys Med Biol Date: 2008-01-10 Impact factor: 3.609

9. Performance evaluation of a depth-of-interaction detector by use of position-sensitive PMT with a super-bialkali photocathode.

Authors: Yoshiyuki Hirano; Munetaka Nitta; Naoko Inadama; Fumihiko Nishikido; Eiji Yoshida; Hideo Murayama; Taiga Yamaya
Journal: Radiol Phys Technol Date: 2013-08-21

9 in total

Analog signal multiplexing for PSAPD-based PET detectors: simulation and experimental validation.

1. Effects of multiple-interaction photon events in a high-resolution PET system that uses 3-D positioning detectors.

2. Performance measurements of a depth-encoding PET detector module based on position-sensitive avalanche photodiode read-out.

3. A new timing model for calculating the intrinsic timing resolution of a scintillator detector.

4. Convex optimization of coincidence time resolution for a high-resolution PET system.

5. The positron emission mammography/tomography breast imaging and biopsy system (PEM/PET): design, construction and phantom-based measurements.

6. PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet.

7. Dedicated PET scanners for breast imaging.

8. Positron emission mammography: high-resolution biochemical breast imaging.

9. Bayesian reconstruction of photon interaction sequences for high-resolution PET detectors.

10. Impact of high energy resolution detectors on the performance of a PET system dedicated to breast cancer imaging.

Review 1. Promising new photon detection concepts for high-resolution clinical and preclinical PET.

2. Optical delay encoding for fast timing and detector signal multiplexing in PET.

3. Convex optimization of coincidence time resolution for a high-resolution PET system.

4. Development of 1.45-mm resolution four-layer DOI-PET detector for simultaneous measurement in 3T MRI.

5. Thermal regulation of tightly packed solid-state photodetectors in a 1 mm(3) resolution clinical PET system.

6. Compact pulse width modulation circuitry for silicon photomultiplier readout.

7. Performance Comparison of Different Readouts for Position-Sensitive Solid-State Photomultiplier Arrays.

8. A Simple Capacitive Charge-Division Readout for Position-Sensitive Solid-State Photomultiplier Arrays.

9. Performance evaluation of a depth-of-interaction detector by use of position-sensitive PMT with a super-bialkali photocathode.