Literature DB >> 15509066

Performance measurements of a depth-encoding PET detector module based on position-sensitive avalanche photodiode read-out.

P A Dokhale1, R W Silverman, K S Shah, R Grazioso, R Farrell, J Glodo, M A McClish, G Entine, V H Tran, S R Cherry.   

Abstract

We are developing a high-resolution, high-efficiency positron emission tomography (PET) detector module with depth of interaction (DOI) capability based on a lutetium oxyorthosilicate (LSO) scintillator array coupled at both ends to position-sensitive avalanche photodiodes (PSAPDs). In this paper we present the DOI resolution, energy resolution and timing resolution results for complete detector modules. The detector module consists of a 7 x 7 matrix of LSO scintillator crystals (1 x 1 x 20 mm3 in dimension) coupled to 8 x 8 mm2 PSAPDs at both ends. Flood histograms were acquired and used to generate crystal look-up tables. The DOI resolution was measured for individual crystals within the array by using the ratio of the signal amplitudes from the two PSAPDs on an event-by-event basis. A measure of the total scintillation light produced was obtained by summing the signal amplitudes from the two PSAPDs. This summed signal was used to measure the energy resolution. The DOI resolution was measured to be 3-4 mm FWHM irrespective of the position of the crystal within the array, or the interaction location along the length of the crystal. The total light signal and energy resolution was almost independent of the depth of interaction. The measured energy resolution averaged 14% FWHM. The coincidence timing resolution measured using a pair of identical detector modules was 4.5 ns FWHM. These results are consistent with the design goals and the performance required of a compact, high-resolution and high-efficiency PET detector module for small animal and breast imaging applications.

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Year:  2004        PMID: 15509066     DOI: 10.1088/0031-9155/49/18/007

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  16 in total

1.  Physical effects of mechanical design parameters on photon sensitivity and spatial resolution performance of a breast-dedicated PET system.

Authors:  V C Spanoudaki; F W Y Lau; A Vandenbroucke; C S Levin
Journal:  Med Phys       Date:  2010-11       Impact factor: 4.071

2.  Depth of interaction calibration for PET detectors with dual-ended readout by PSAPDs.

Authors:  Yongfeng Yang; Jinyi Qi; Yibao Wu; Sara St James; Richard Farrell; Purushottam A Dokhale; Kanai S Shah; Simon R Cherry
Journal:  Phys Med Biol       Date:  2008-12-19       Impact factor: 3.609

3.  A New Positioning Algorithm for Position-Sensitive Avalanche Photodiodes.

Authors:  Jin Zhang; Peter D Olcott; Craig S Levin
Journal:  IEEE Trans Nucl Sci       Date:  2007-06-01       Impact factor: 1.679

Review 4.  Innovations in Instrumentation for Positron Emission Tomography.

Authors:  Eric Berg; Simon R Cherry
Journal:  Semin Nucl Med       Date:  2018-03-12       Impact factor: 4.446

5.  Experimental characterization and system simulations of depth of interaction PET detectors using 0.5 mm and 0.7 mm LSO arrays.

Authors:  Sara St James; Yongfeng Yang; Yibao Wu; Richard Farrell; Purushottam Dokhale; Kanai S Shah; Simon R Cherry
Journal:  Phys Med Biol       Date:  2009-06-30       Impact factor: 3.609

6.  Effect of CZT system characteristics on Compton scatter event recovery.

Authors:  Sheng Yang; Mohan Li; Michael Reed; James Hugg; Henry Chen; Shiva Abbaszadeh
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2019-05-06

7.  Effects of reflector and crystal surface on the performance of a depth-encoding PET detector with dual-ended readout.

Authors:  Silin Ren; Yongfeng Yang; Simon R Cherry
Journal:  Med Phys       Date:  2014-07       Impact factor: 4.071

8.  Efficient one-pair experimental system for spatial resolution demonstration of prototype PET detectors.

Authors:  Hideaki Tashima; Eiji Yoshida; Yoshiyuki Hirano; Fumihiko Nishikido; Naoko Inadama; Hideo Murayama; Taiga Yamaya
Journal:  Radiol Phys Technol       Date:  2014-06-18

Review 9.  Breast cancer imaging: a perspective for the next decade.

Authors:  Andrew Karellas; Srinivasan Vedantham
Journal:  Med Phys       Date:  2008-11       Impact factor: 4.071

10.  Performance evaluation of a depth-of-interaction detector by use of position-sensitive PMT with a super-bialkali photocathode.

Authors:  Yoshiyuki Hirano; Munetaka Nitta; Naoko Inadama; Fumihiko Nishikido; Eiji Yoshida; Hideo Murayama; Taiga Yamaya
Journal:  Radiol Phys Technol       Date:  2013-08-21
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