Literature DB >> 26233181

Optical delay encoding for fast timing and detector signal multiplexing in PET.

Alexander M Grant1, Craig S Levin2.   

Abstract

PURPOSE: The large number of detector channels in modern positron emission tomography (PET) scanners poses a challenge in terms of readout electronics complexity. Multiplexing schemes are typically implemented to reduce the number of physical readout channels, but often result in performance degradation. Novel methods of multiplexing in PET must be developed to avoid this data degradation. The preservation of fast timing information is especially important for time-of-flight PET.
METHODS: A new multiplexing scheme based on encoding detector interaction events with a series of extremely fast overlapping optical pulses with precise delays is demonstrated in this work. Encoding events in this way potentially allows many detector channels to be simultaneously encoded onto a single optical fiber that is then read out by a single digitizer. A two channel silicon photomultiplier-based prototype utilizing this optical delay encoding technique along with dual threshold time-over-threshold is demonstrated.
RESULTS: The optical encoding and multiplexing prototype achieves a coincidence time resolution of 160 ps full width at half maximum (FWHM) and an energy resolution of 13.1% FWHM at 511 keV with 3 × 3 × 5 mm(3) LYSO crystals. All interaction information for both detectors, including timing, energy, and channel identification, is encoded onto a single optical fiber with little degradation.
CONCLUSIONS: Optical delay encoding and multiplexing technology could lead to time-of-flight PET scanners with fewer readout channels and simplified data acquisition systems.

Mesh:

Year:  2015        PMID: 26233181      PMCID: PMC4499043          DOI: 10.1118/1.4923176

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  13 in total

1.  Prototype positron emission tomography insert with electro-optical signal transmission for simultaneous operation with MRI.

Authors:  Peter Olcott; Ealgoo Kim; Keyjo Hong; Brian J Lee; Alexander M Grant; Chen-Ming Chang; Gary Glover; Craig S Levin
Journal:  Phys Med Biol       Date:  2015-04-09       Impact factor: 3.609

2.  Convex optimization of coincidence time resolution for a high-resolution PET system.

Authors:  Paul D Reynolds; Peter D Olcott; Guillem Pratx; Frances W Y Lau; Craig S Levin
Journal:  IEEE Trans Med Imaging       Date:  2010-09-27       Impact factor: 10.048

3.  Experimental demonstration of two methods for controlling the group delay in a system with photonic-crystal resonators coupled to a waveguide.

Authors:  Yijie Huo; Sunil Sandhu; Jun Pan; Norbert Stuhrmann; Michelle L Povinelli; Joseph M Kahn; James S Harris; Martin M Fejer; Shanhui Fan
Journal:  Opt Lett       Date:  2011-04-15       Impact factor: 3.776

4.  A Digital Preclinical PET/MRI Insert and Initial Results.

Authors:  Bjoern Weissler; Pierre Gebhardt; Peter M Dueppenbecker; Jakob Wehner; David Schug; Christoph W Lerche; Benjamin Goldschmidt; Andre Salomon; Iris Verel; Edwin Heijman; Michael Perkuhn; Dirk Heberling; Rene M Botnar; Fabian Kiessling; Volkmar Schulz
Journal:  IEEE Trans Med Imaging       Date:  2015-04-29       Impact factor: 10.048

5.  19-core MCF transmission system using EDFA with shared core pumping coupled via free-space optics.

Authors:  Jun Sakaguchi; Werner Klaus; Benjamin J Puttnam; José Manuel Delgado Mendinueta; Yoshinari Awaji; Naoya Wada; Yukihiro Tsuchida; Koichi Maeda; Masateru Tadakuma; Katsunori Imamura; Ryuichi Sugizaki; Tetsuya Kobayashi; Yusaku Tottori; Masayuki Watanabe; R V Jensen
Journal:  Opt Express       Date:  2014-01-13       Impact factor: 3.894

6.  A new dual threshold time-over-threshold circuit for fast timing in PET.

Authors:  Alexander M Grant; Craig S Levin
Journal:  Phys Med Biol       Date:  2014-06-03       Impact factor: 3.609

7.  Analog signal multiplexing for PSAPD-based PET detectors: simulation and experimental validation.

Authors:  Frances W Y Lau; Arne Vandenbroucke; Paul D Reynolds; Peter D Olcott; Mark A Horowitz; Craig S Levin
Journal:  Phys Med Biol       Date:  2010-11-16       Impact factor: 3.609

8.  Investigation of analog charge multiplexing schemes for SiPM based PET block detectors.

Authors:  Evan Downie; Xin Yang; Hao Peng
Journal:  Phys Med Biol       Date:  2013-05-16       Impact factor: 3.609

9.  Optimizing timing performance of silicon photomultiplier-based scintillation detectors.

Authors:  Jung Yeol Yeom; Ruud Vinke; Craig S Levin
Journal:  Phys Med Biol       Date:  2013-01-31       Impact factor: 3.609

10.  PET/MRI insert using digital SiPMs: Investigation of MR-compatibility.

Authors:  Jakob Wehner; Bjoern Weissler; Peter Dueppenbecker; Pierre Gebhardt; David Schug; Walter Ruetten; Fabian Kiessling; Volkmar Schulz
Journal:  Nucl Instrum Methods Phys Res A       Date:  2014-01-11       Impact factor: 1.455

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