Literature DB >> 19258685

Continuous depth-of-interaction encoding using phosphor-coated scintillators.

Huini Du1, Yongfeng Yang, Jarek Glodo, Yibao Wu, Kanai Shah, Simon R Cherry.   

Abstract

We investigate a novel detector using a lutetium oxyorthosilicate (LSO) scintillator and YGG (yttrium-aluminum-gallium oxide:cerium, Y(3)(Al,Ga)(5)O(12):Ce) phosphor to construct a detector with continuous depth-of-interaction (DOI) information. The far end of the LSO scintillator is coated with a thin layer of YGG phosphor powder which absorbs some fraction of the LSO scintillation light and emits wavelength-shifted photons with a characteristic decay time of approximately 50 ns. The near end of the LSO scintillator is directly coupled to a photodetector. The photodetector detects a mixture of the LSO light and the light emitted by YGG. With appropriate placement of the coating, the ratio of the light converted from the YGG coating with respect to the unconverted LSO light can be made to depend on the interaction depth. DOI information can then be estimated by inspecting the overall light pulse decay time. Experiments were conducted to optimize the coating method. 19 ns decay time differences across the length of the detector were achieved experimentally when reading out a 1.5 x 1.5 x 20 mm(3) LSO crystal with unpolished surfaces and half-coated with YGG phosphor. The same coating scheme was applied to a 4 x 4 LSO array. Pulse shape discrimination (PSD) methods were studied to extract DOI information from the pulse shape changes. The DOI full-width-half-maximum (FWHM) resolution was found to be approximately 8 mm for this 2 cm thick array.

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Year:  2009        PMID: 19258685      PMCID: PMC2748919          DOI: 10.1088/0031-9155/54/6/023

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  6 in total

1.  Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors.

Authors:  Martin S Judenhofer; Bernd J Pichler; Simon R Cherry
Journal:  Phys Med Biol       Date:  2005-01-07       Impact factor: 3.609

2.  Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes.

Authors:  Yongfeng Yang; Purushottam A Dokhale; Robert W Silverman; Kanai S Shah; Mickel A McClish; Richard Farrell; Gerald Entine; Simon R Cherry
Journal:  Phys Med Biol       Date:  2006-04-10       Impact factor: 3.609

3.  Measurements of wavelength shifting (WLS) fibre readout for a highly multiplexed, depth-encoding PET detector.

Authors:  Huini Du; Yongfeng Yang; Simon R Cherry
Journal:  Phys Med Biol       Date:  2007-04-10       Impact factor: 3.609

4.  Comparison of four depth-encoding PET detector modules with wavelength shifting (WLS) and optical fiber read-out.

Authors:  Huini Du; Yongfeng Yang; Simon R Cherry
Journal:  Phys Med Biol       Date:  2008-03-10       Impact factor: 3.609

5.  Performance evaluation of the GE healthcare eXplore VISTA dual-ring small-animal PET scanner.

Authors:  Yuchuan Wang; Jurgen Seidel; Benjamin M W Tsui; Juan J Vaquero; Martin G Pomper
Journal:  J Nucl Med       Date:  2006-11       Impact factor: 10.057

6.  A prototype PET scanner with DOI-encoding detectors.

Authors:  Yongfeng Yang; Yibao Wu; Jinyi Qi; Sara St James; Huini Du; Purushottam A Dokhale; Kanai S Shah; Richard Farrell; Simon R Cherry
Journal:  J Nucl Med       Date:  2008-06-13       Impact factor: 10.057

  6 in total
  15 in total

Review 1.  Innovations in Instrumentation for Positron Emission Tomography.

Authors:  Eric Berg; Simon R Cherry
Journal:  Semin Nucl Med       Date:  2018-03-12       Impact factor: 4.446

2.  DOI Determination by Rise Time Discrimination in Single-Ended Readout for TOF PET Imaging.

Authors:  R I Wiener; S Surti; J S Karp
Journal:  IEEE Trans Nucl Sci       Date:  2013-06       Impact factor: 1.679

3.  Side readout of long scintillation crystal elements with digital SiPM for TOF-DOI PET.

Authors:  Jung Yeol Yeom; Ruud Vinke; Craig S Levin
Journal:  Med Phys       Date:  2014-12       Impact factor: 4.071

4.  A depth-of-interaction encoding PET detector module with dual-ended readout using large-area silicon photomultiplier arrays.

Authors:  Junwei Du; Xiaowei Bai; Simon R Cherry
Journal:  Phys Med Biol       Date:  2018-12-14       Impact factor: 3.609

5.  Reaching 200-ps timing resolution in a time-of-flight and depth-of-interaction positron emission tomography detector using phosphor-coated crystals and high-density silicon photomultipliers.

Authors:  Sun Il Kwon; Alessandro Ferri; Alberto Gola; Eric Berg; Claudio Piemonte; Simon R Cherry; Emilie Roncali
Journal:  J Med Imaging (Bellingham)       Date:  2016-11-23

6.  Simulation of light transport in scintillators based on 3D characterization of crystal surfaces.

Authors:  Emilie Roncali; Simon R Cherry
Journal:  Phys Med Biol       Date:  2013-03-11       Impact factor: 3.609

7.  A DOI Detector With Crystal Scatter Identification Capability for High Sensitivity and High Spatial Resolution PET Imaging.

Authors:  Z Gu; D L Prout; R W Silverman; H Herman; A Dooraghi; A F Chatziioannou
Journal:  IEEE Trans Nucl Sci       Date:  2015-06       Impact factor: 1.679

8.  Characterization of stacked-crystal PET detector designs for measurement of both TOF and DOI.

Authors:  Jeffrey P Schmall; Suleman Surti; Joel S Karp
Journal:  Phys Med Biol       Date:  2015-04-10       Impact factor: 3.609

9.  Tapered LSO arrays for small animal PET.

Authors:  Yongfeng Yang; Sara St James; Yibao Wu; Huini Du; Jinyi Qi; Richard Farrell; Purushottam A Dokhale; Kanai S Shah; Keith Vaigneur; Simon R Cherry
Journal:  Phys Med Biol       Date:  2010-11-30       Impact factor: 3.609

10.  Pulse shape discrimination and classification methods for continuous depth of interaction encoding PET detectors.

Authors:  Emilie Roncali; Jennifer E Phipps; Laura Marcu; Simon R Cherry
Journal:  Phys Med Biol       Date:  2012-09-25       Impact factor: 3.609

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