Literature DB >> 18364543

Characterizing the response of miniature scintillation detectors when irradiated with proton beams.

Louis Archambault1, Jerimy C Polf, Luc Beaulieu, Sam Beddar.   

Abstract

Designing a plastic scintillation detector for proton radiation therapy requires careful consideration. Most of the plastic scintillators should not perturb a proton beam if they are sufficiently small but may exhibit some energy dependence due to the quenching effect. In this work, we studied the factors that would affect the performance of such scintillation detectors. We performed Monte Carlo simulations of proton beams with energies between 50 and 250 MeV to study signal amplitude, water equivalence, spatial resolution and quenching of light output. Implementation of the quenching effect in the Monte Carlo simulations was then compared with prior experimental data for validation. The signal amplitude of a plastic scintillating fiber detector was on the order of 300 photons per MeV of energy deposited in the detector, corresponding to a power of about 30 pW at a proton dose rate of 100 cGy min(-1). The signal amplitude could be increased by up to a factor of 2 with reflective coating. We also found that Cerenkov light was not a significant source of noise. Dose deposited in the plastic scintillator was within 2% of the dose deposited in a similar volume of water throughout the whole depth-dose curve for protons with energies higher than 50 MeV. A scintillation detector with a radius of 0.5 mm offers a sufficient spatial resolution for use with a proton beam of 100 MeV or more. The main disadvantage of plastic scintillators when irradiated by protons was the quenching effect, which reduced the amount of scintillation and resulted in dose underestimation by close to 30% at the Bragg peak for beams of 150 MeV or more. However, the level of quenching was nearly constant throughout the proximal half of the depth-dose curve for all proton energies considered. We therefore conclude that it is possible to construct an effective detector to overcome the problems traditionally encountered in proton dosimetry. Scintillation detectors could be used for surface or shallow measurements with a single calibration for specific beam energy. For deeper measurements, Monte Carlo simulations can be used to generate depth-dependent correction factors.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18364543      PMCID: PMC3987823          DOI: 10.1088/0031-9155/53/7/004

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  11 in total

1.  Comments on ICRU report no. 49: stopping powers and ranges for protons and alpha particles.

Authors:  J F Ziegler
Journal:  Radiat Res       Date:  1999-08       Impact factor: 2.841

2.  Test of GEANT3 and GEANT4 nuclear models for 160 MeV protons stopping in CH2.

Authors:  H Paganetti; B Gottschalk
Journal:  Med Phys       Date:  2003-07       Impact factor: 4.071

3.  Model of ion-induced luminescence based on energy deposition by secondary electrons.

Authors: 
Journal:  Phys Rev B Condens Matter       Date:  1994-06-01

4.  Accurate Monte Carlo simulations for nozzle design, commissioning and quality assurance for a proton radiation therapy facility.

Authors:  H Paganetti; H Jiang; S Y Lee; H M Kooy
Journal:  Med Phys       Date:  2004-07       Impact factor: 4.071

5.  Development of an inorganic scintillating mixture for proton beam verification dosimetry.

Authors:  Sairos Safai; Shixiong Lin; Eros Pedroni
Journal:  Phys Med Biol       Date:  2004-10-07       Impact factor: 3.609

6.  Plastic scintillation dosimetry: optimal selection of scintillating fibers and scintillators.

Authors:  Louis Archambault; Jean Arsenault; Luc Gingras; A Sam Beddar; René Roy; Luc Beaulieu
Journal:  Med Phys       Date:  2005-07       Impact factor: 4.071

7.  Measurement accuracy and cerenkov removal for high performance, high spatial resolution scintillation dosimetry.

Authors:  Louis Archambault; A Sam Beddar; Luc Gingras; René Roy; Luc Beaulieu
Journal:  Med Phys       Date:  2006-01       Impact factor: 4.071

8.  Proton dosimetry intercomparison based on the ICRU report 59 protocol.

Authors:  S Vatnitsky; M Moyers; D Miller; G Abell; J M Slater; E Pedroni; A Coray; A Mazal; W Newhauser; O Jaekel; J Heese; A Fukumura; Y Futami; L Verhey; I Daftari; E Grusell; A Molokanov; C Bloch
Journal:  Radiother Oncol       Date:  1999-06       Impact factor: 6.280

9.  Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: II. Properties and measurements.

Authors:  A S Beddar; T R Mackie; F H Attix
Journal:  Phys Med Biol       Date:  1992-10       Impact factor: 3.609

10.  Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: I. Physical characteristics and theoretical consideration.

Authors:  A S Beddar; T R Mackie; F H Attix
Journal:  Phys Med Biol       Date:  1992-10       Impact factor: 3.609

View more
  13 in total

1.  Verification of proton range, position, and intensity in IMPT with a 3D liquid scintillator detector system.

Authors:  L Archambault; F Poenisch; N Sahoo; D Robertson; A Lee; M T Gillin; R Mohan; S Beddar
Journal:  Med Phys       Date:  2012-03       Impact factor: 4.071

2.  Monte Carlo study of the energy and angular dependence of the response of plastic scintillation detectors in photon beams.

Authors:  Lilie L W Wang; David Klein; A Sam Beddar
Journal:  Med Phys       Date:  2010-10       Impact factor: 4.071

3.  Extraction of depth-dependent perturbation factors for parallel-plate chambers in electron beams using a plastic scintillation detector.

Authors:  Frédéric Lacroix; Mathieu Guillot; Malcolm McEwen; Claudiu Cojocaru; Luc Gingras; A Sam Beddar; Luc Beaulieu
Journal:  Med Phys       Date:  2010-08       Impact factor: 4.071

4.  Exploration of the potential of liquid scintillators for real-time 3D dosimetry of intensity modulated proton beams.

Authors:  Sam Beddar; Louis Archambault; Narayan Sahoo; Falk Poenisch; George T Chen; Michael T Gillin; Radhe Mohan
Journal:  Med Phys       Date:  2009-05       Impact factor: 4.071

5.  Real-time dosimetry in external beam radiation therapy.

Authors:  Ramachandran Prabhakar
Journal:  World J Radiol       Date:  2013-10-28

6.  Fast range measurement of spot scanning proton beams using a volumetric liquid scintillator detector.

Authors:  CheukKai Hui; Daniel Robertson; Fahed Alsanea; Sam Beddar
Journal:  Biomed Phys Eng Express       Date:  2015-07-30

7.  Simulation of the precision limits of plastic scintillation detectors using optimal component selection.

Authors:  Frédéric Lacroix; Luc Beaulieu; Louis Archambault; A Sam Beddar
Journal:  Med Phys       Date:  2010-02       Impact factor: 4.071

8.  A design methodology using signal-to-noise ratio for plastic scintillation detectors design and performance optimization.

Authors:  Frédéric Lacroix; A Sam Beddar; Mathieu Guillot; Luc Beaulieu; Luc Gingras
Journal:  Med Phys       Date:  2009-11       Impact factor: 4.071

9.  Passively scattered proton beam entrance dosimetry with a plastic scintillation detector.

Authors:  Landon Wootton; Charles Holmes; Narayan Sahoo; Sam Beddar
Journal:  Phys Med Biol       Date:  2015-01-15       Impact factor: 3.609

10.  Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams.

Authors:  L L W Wang; L A Perles; L Archambault; N Sahoo; D Mirkovic; S Beddar
Journal:  Phys Med Biol       Date:  2012-11-06       Impact factor: 3.609

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.