| Literature DB >> 18343979 |
F Harald R De Man1, Daniel Haverkamp, Harm M Van der Vis, Philip P Besselaar, René K Marti.
Abstract
UNLABELLED: Total hip arthroplasty in hypoplastic femurs is technically difficult and the incidence of complications and aseptic loosening is relatively high. Cemented, uncemented, off-the-shelf, and custom-made stems all have been advocated in these cases. From 1978 to 1997, we performed 86 total hip arthroplasties in 77 patients with a hypoplastic femur using a cemented, off-the-shelf, small, curved, cobalt-chromium stem. We hypothesized results equaled those of the identical but larger-sized stems in normal-sized femora which were used as comparisons. Clinical and radiographic evaluations were performed. Minimum followup was 4.2 years (mean, 12 years; range, 4.2-20.3 years); mean Harris hip score was 88, and mean hip flexion was 104 degrees . Six stems were revised: four because of aseptic loosening, one after a femoral fracture, and one because of malpositioning. Complications included one perforation and one fracture of the femur, one fracture, one nonunion of the greater trochanter, and one deep infection. Implant survivorship for all hips at 15 years with aseptic revision of the stem as the end point was 90% (confidence interval, 82-99) which equaled results of the larger stems. The small off-the-shelf cemented Weber stem has a high long-term survival and a low complication rate. Survival compares favorably with other small-sized total hip systems. LEVEL OF EVIDENCE: Level III, therapeutic study, case-control.Entities:
Mesh:
Year: 2008 PMID: 18343979 PMCID: PMC2384046 DOI: 10.1007/s11999-008-0190-y
Source DB: PubMed Journal: Clin Orthop Relat Res ISSN: 0009-921X Impact factor: 4.176
Fig. 1This preoperative radiograph shows the left hip of a 49-year-old woman with bilateral femoral hypoplasia in the presence of developmental dysplasia of the hip and secondary OA.
Patient demographics
| Demographics | Hypoplastic group | Normal anatomy group |
|---|---|---|
| Number of patients (hips) | 77 (86)1 | 198 (231) |
| Man : Woman | 4 : 732 | 81 : 117 |
| Median age, years (range) | 65 (23–80)3 | 69 (36–85) |
| Mean followup, years (range) | 11.7 (4.2–20.3)4 | 16.1 (4.7–23.7) |
| Median weight, kg (range) | 64 (38–111)5 | 68 (46–115) |
| Median height, cm (range) | 160 (143–189)6 | 168 (144–192) |
| Median body mass index | 25.2 (16.9–41.1)7 | 24.5 (18.4–37.2) |
| Preoperative diagnosis (%) | 8 | |
| DDH | 71/86 (83%) | 58/231 (25%) |
| Primary OA | 5/86 (6%) | 148/231 (64%) |
| Posttraumatic OA | 5/86 (6%) | 7/231 (3%) |
| Osteonecrosis | 4/86 (5%) | 2/231 (1%) |
| Reumatoid arthritis | 1/86 (1%) | 58/231 (25%) |
| Other | 0/86 (0%) | 8/231 (3%) |
| Number of previous hip surgeries (%) | 35/86 (41%)9 | 53/231 (23%) |
Statistical differences between the two groups:
1 Student’s t-test, p < 0.01.
2 chi square, p < 0.01.
3 Student’s t-test, p < 0.01.
4 Student’s t-test, p < 0.01.
5 Mann-Whitney U, p < 0.03.
6 Student’s t-test, p < 0.01.
7 chi square, p = 0.58.
8 chi square, p < 0.01.
9 chi square, p < 0.01.
Specifics of surgery and results
| Data for surgery | Hypoplastic group | Normal anatomy group |
|---|---|---|
| Number of trochanteric osteotomies | 22/86 (26%)1 | 30/231 (13%) |
| Number of acetabular roofplasties | 22/86 (26%)2 | 64/231 (28%) |
| Spherical cup : flat cup | 69 : 15 | NR |
| Ceramic : metal heads | 42 : 423 | 143 : 83 |
| Mean HHS (range) | 88 (51–100)4 | 89 (53–100) |
| Number of surgery-related complications (%) | 4/86 (5%)5 | 12/231 (5%) |
| Number of aseptic loosening stems (%) | 6/86 (7%)6 | 16/231 (7%) |
| Number of aseptic loosening cups (%) | 4/86 (5%)7 | 15/231 (6%) |
NR = not reported; Statistical differences between groups:
1 chi square, p < 0.01.
2 chi square, p = 0.59.
3 chi square, p = 0.03.
4 Student’s t-test, p = 0.55.
5 chi square, p = 0.84.
6 chi square, p = 0.99.
7 chi square, p = 0.54.
Fig. 2In this picture, the hemispheric (left) and flat (right) socket with the curved stem of the 102 size Weber rotation total hip prosthesis with Protasul (right) and ceramic (left) heads with a trunnion bearing are shown.
Fig. 3The postoperative radiograph shows a 102-sized Weber stem on the left and a larger 103 stem on the right after a trochanteric osteotomy with bilateral 52-mm cemented cups and roofplasties 17 and 18 years, respectively, after the index operation. No demarcation around the components is seen. The acetabular roofplasties are completely integrated and the trochanteric osteotomy is healed. Periacetabular ossifications (Grade II according to Brooker) were asymptomatic. The Harris hip score at the time of the last followup was 87 points for the left side and 100 points for the right side.
Survival analysis according to the life-table method with different end points
| End point | Hypoplastic group (86 hips) | Normal anatomy group (231 hips) |
|---|---|---|
| Survival rate at 15-years (95% CI) | Survival rate at 15-years (95% CI) | |
| Revision for any reason | ||
| Stem | 90% (CI, 82–99)1 | 89% (CI, 84–94) |
| Cup | 91% (CI, 83–100)2 | 92% (CI, 87–96) |
| Revision for aseptic loosening | ||
| Stem | 90% (CI, 82–99)3 | 93% (CI, 89–97) |
| Cup | 91% (CI, 83–100)4 | 94% (CI, 90–98) |
| Radiologic loosening | ||
| Stem | 89% (CI, 79–99)5 | 86% (CI, 80–92) |
| Cup | 91% (CI, 82–100)6 | 89% (CI, 83–95) |
CI = confidence interval; Hypoplastic vs. normal anatomy group (log rank test):
1p = 0.79.
2p = 0.50.
3P = 0.26.
4p = 0.40.
5p = 0.67.
6p = 0.77.
Cox regression analysis: outcome revision aseptic stem corrected for length and gender showed no significant difference, p = 0.22; outcome revision aseptic cup corrected for length and gender showed no significant difference, p = 0.07.
Time between index operation and revision of components and reason for revision
| Acetabular component (years) | Femoral component (years) | Acetabular/Femoral |
|---|---|---|
| — | 6.2 | Aseptic loosening |
| — | 17 | Aseptic loosening |
| 5.7 | 5.7 | Aseptic loosening |
| 12.9 | 12.9 | Aseptic loosening |
| 10.5 | 7.5 | Aseptic loosening/shaft fracture |
| 7.8 | 7.8 | Aseptic loosening/malpositioning |
| 15.3 | — | Wear |
Results of studies with identical stem design or with diagnosis of femoral hypoplasia with or without dysplasia
| Type of prosthesis/stem design | Authors | Percent survivorship analysis with an end point of aseptic stem loosening (95% CI) | Revision rate of aseptic or stem fracture (%) | Complication rate (%) | Number of hips | Median height (cm) | Mean followup (years) |
|---|---|---|---|---|---|---|---|
|
| |||||||
| Off-the-shelf Weber, curved cemented all sizes | De Jong et al. [ | 82% (CI, NR) at 15 years | 7 | NR | 315 | NR | 10.5 |
|
| |||||||
| Off-the-shelf Charnley, cemented | Iida et al. [ | 94% (88–100) at 15 years | 4 | 20 | 133 | 150 | 12 |
| Off-the-shelf Charnley, cemented | MacKenzie et al. [ | 97% (CI, NR) at 15 years | 5 | NR | 66 | NR | 25 |
| Off-the-shelf AML, uncemented | Oh et al. [ | 97% (CI, NR) at 12 years | 5 | 0 | 40 | 157 | 7 |
| Off-the-shelf AML, cemented | 77% (CI, NR) at 12 years | 25 | 0 | 12 | |||
| Custom-made straight/offset cemented | Huo et al. [ | NR | 6 | 0 | 19 | 152 | 13 |
| Customized CDH, straight cemented | Woolson and Harris [ | NR | 5.5 | 19 | 69 | 156 | 5 |
CI = confidence interval; DDH, developmental dysplasia of the hip; NR = not reported in the study.