Literature DB >> 1605601

Glycosylation of macrolide antibiotics in extracts of Streptomyces lividans.

E Cundliffe1.   

Abstract

Inducible resistance to macrolide antibiotics in Streptomyces lividans involves MGT, a macrolide glycosyl transferase that utilizes UDP-glucose as cofactor. Substrates for MGT include macrolides with 12-, 14-, 15-, or 16-atom cyclic polyketide lactones (as in methymycin, erythromycin, azithromycin, or tylosin, respectively), although spiramycin and carbomycin are not apparently modified. The enzyme is specific for the 2'-OH group of saccharidic moieties attached to C-5 of the 16-atom lactone ring (corresponding to C-5 or C-3 in 14- or 12-atom lactones, respectively).

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Year:  1992        PMID： 1605601      PMCID： PMC188440          DOI： 10.1128/AAC.36.2.348

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Microbial glycosylation of erythromycin A.

Authors:  M S Kuo; D G Chirby; A D Argoudelis; J I Cialdella; J H Coats; V P Marshall
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

2.  Inducible ribosomal RNA methylation in Streptomyces lividans, conferring resistance to lincomycin.

Authors:  G Jenkins; M Zalacain; E Cundliffe
Journal:  J Gen Microbiol       Date:  1989-12

3.  Purification and characterization of macrolide 2'-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin.

Authors:  K O'Hara; T Kanda; K Ohmiya; T Ebisu; M Kono
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

4.  Microbial O-phosphorylation of macrolide antibiotics.

Authors:  V P Marshall; J I Cialdella; L Baczynskyj; W F Liggett; R A Johnson
Journal:  J Antibiot (Tokyo)       Date:  1989-01       Impact factor: 2.649

5.  Methylation of 16S ribosomal RNA and resistance to aminoglycoside antibiotics in clones of Streptomyces lividans carrying DNA from Streptomyces tenjimariensis.

Authors:  P A Skeggs; J Thompson; E Cundliffe
Journal:  Mol Gen Genet       Date:  1985

6.  Enzymatic phosphorylation of macrolide antibiotics.

Authors:  P F Wiley; L Baczynskyj; L A Dolak; J I Cialdella; V P Marshall
Journal:  J Antibiot (Tokyo)       Date:  1987-02       Impact factor: 2.649

7.  Two promoters, one inducible and one constitutive, control transcription of the Streptomyces lividans galactose operon.

Authors:  J A Fornwald; F J Schmidt; C W Adams; M Rosenberg; M E Brawner
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

8.  Methylation of 23S ribosomal RNA due to carB, an antibiotic-resistance determinant from the carbomycin producer, Streptomyces thermotolerans.

Authors:  M Zalacain; E Cundliffe
Journal:  Eur J Biochem       Date:  1990-04-20

9.  Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics.

Authors:  G Jenkins; E Cundliffe
Journal:  Gene       Date:  1991-12-01       Impact factor: 3.688

10.  Plasmids, recombination and chromosome mapping in Streptomyces lividans 66.

Authors:  D A Hopwood; T Kieser; H M Wright; M J Bibb
Journal:  J Gen Microbiol       Date:  1983-07
  10 in total
  15 in total

1.  Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis.

Authors:  S L Otten; X Liu; J Ferguson; C R Hutchinson
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

2.  Induction of ermSV by 16-membered-ring macrolide antibiotics.

Authors:  S Kamimiya; B Weisblum
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

Review 3.  Comparison of Antibiotic Resistance Mechanisms in Antibiotic-Producing and Pathogenic Bacteria.

Authors:  Hiroshi Ogawara
Journal:  Molecules       Date:  2019-09-21       Impact factor: 4.411

4.  Ribosylation by mycobacterial strains as a new mechanism of rifampin inactivation.

Authors:  E R Dabbs; K Yazawa; Y Mikami; M Miyaji; N Morisaki; S Iwasaki; K Furihata
Journal:  Antimicrob Agents Chemother       Date:  1995-04       Impact factor: 5.191

5.  Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.

Authors:  E Fernández; U Weissbach; C Sánchez Reillo; A F Braña; C Méndez; J Rohr; J A Salas
Journal:  J Bacteriol       Date:  1998-09       Impact factor: 3.490

6.  The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans.

Authors:  J L Pernodet; S Fish; M H Blondelet-Rouault; E Cundliffe
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

7.  Microbial conversion of avermectins by Saccharopolyspora erythraea: glycosylation at C-4' and C-4''.

Authors:  M Schulman; P Doherty; B Arison
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

8.  Characterization of a glycosyl transferase inactivating macrolides, encoded by gimA from Streptomyces ambofaciens.

Authors:  A Gourmelen; M H Blondelet-Rouault; J L Pernodet
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191

Review 9.  The Complex Relationship between Virulence and Antibiotic Resistance.

Authors:  Meredith Schroeder; Benjamin D Brooks; Amanda E Brooks
Journal:  Genes (Basel)       Date:  2017-01-18       Impact factor: 4.096

Review 10.  Look and Outlook on Enzyme-Mediated Macrolide Resistance.

Authors:  Tolou Golkar; Michał Zieliński; Albert M Berghuis
Journal:  Front Microbiol       Date:  2018-08-20       Impact factor: 5.640
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