Literature DB >> 3570968

Enzymatic phosphorylation of macrolide antibiotics.

P F Wiley, L Baczynskyj, L A Dolak, J I Cialdella, V P Marshall.   

Abstract

Five macrolide antibiotics (erythromycin A, 1; oleandomycin, 3a; tylosin, 4a; spiramycins, 5a; leucomycin A3, 6a) have been phosphorylated enzymatically using cell-free extracts derived from Streptomyces coelicolor UC 5240. The necessary cofactors and the rates of the conversion have been determined.

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Year:  1987        PMID： 3570968     DOI： 10.7164/antibiotics.40.195

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

1.  Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus.

Authors:  C Vilches; C Hernandez; C Mendez; J A Salas
Journal:  J Bacteriol       Date:  1992-01       Impact factor: 3.490

Review 2.  Avoidance of suicide in antibiotic-producing microbes.

Authors:  Eric Cundliffe; Arnold L Demain
Journal:  J Ind Microbiol Biotechnol       Date:  2010-05-06       Impact factor: 3.346

3.  Microbial glycosylation of erythromycin A.

Authors:  M S Kuo; D G Chirby; A D Argoudelis; J I Cialdella; J H Coats; V P Marshall
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

4.  Purification and characterization of macrolide 2'-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin.

Authors:  K O'Hara; T Kanda; K Ohmiya; T Ebisu; M Kono
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

5.  Binding of novel macrolide structures to macrolides-lincosamides-streptogramin B-resistant ribosomes inhibits protein synthesis and bacterial growth.

Authors:  R C Goldman; S K Kadam
Journal:  Antimicrob Agents Chemother       Date:  1989-07       Impact factor: 5.191

6.  Glycosylation of macrolide antibiotics in extracts of Streptomyces lividans.

Authors:  E Cundliffe
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191

7.  Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species.

Authors:  K Yazawa; Y Mikami; T Sakamoto; Y Ueno; N Morisaki; S Iwasaki; K Furihata
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

8.  Role of an energy-dependent efflux pump in plasmid pNE24-mediated resistance to 14- and 15-membered macrolides in Staphylococcus epidermidis.

Authors:  R C Goldman; J O Capobianco
Journal:  Antimicrob Agents Chemother       Date:  1990-10       Impact factor: 5.191

9.  Innovative Perspectives on Biofilm Interactions in Poultry Drinking Water Systems and Veterinary Antibiotics Used Worldwide.

Authors:  Friederike Hahne; Simon Jensch; Gerd Hamscher; Jessica Meißner; Manfred Kietzmann; Nicole Kemper; Jochen Schulz; Rafael H Mateus-Vargas
Journal:  Antibiotics (Basel)       Date:  2022-01-09
  9 in total

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