OBJECTIVE: To test the effects of low perfusion caused by emerging sepsis on the performance of two new pulse oximetry techniques: Masimo SET in comparison with Nellcor Oxismart XL. DESIGN: Cohort study with random allocation of two pulse oximetry devices to two sensor sites. SETTING. University animal research facility. SUBJECTS: Twenty-five adult, anesthetized, ventilated rabbits. INTERVENTIONS: Pneumonia/sepsis was induced by tracheal instillation of E. coli. MEASUREMENTS AND RESULTS: Oxygen saturation was measured by pulse oximetry (SpO(2)) and recorded continuously until death. Arterial oxygen saturation (SaO(2)) was measured hourly by CO oximetry and whenever a difference of >5% between the devices occurred. SpO(2) sensors were positioned at both forelegs and switched hourly. There was no difference in total signal dropout time [median 3.8 min (range 0.4-66.6 min) vs 3.3 min (range 0-94.5 min), Masimo SET vs Oxismart XL]. There were fewer episodes with a false SpO(2) reading [1 (range 0-7) vs 2 (range 0-17)] using the Masimo SET vs the Oxismart XL as verified by CO oximetry; p<0.05. Average bias (SpO(2)-SaO(2)) was significantly different between the two devices, and variability of bias values increased across time with both devices. CONCLUSIONS: Both devices were capable to measure SpO(2) during most of the experimental time in this model of low perfusion and therefore appear to be highly sensitive to pick up a signal; however, low perfusion caused by emerging sepsis may result in inaccurate measurements with both devices. These episodes were less common with the Masimo SET vs the Oxismart XL.
OBJECTIVE: To test the effects of low perfusion caused by emerging sepsis on the performance of two new pulse oximetry techniques: Masimo SET in comparison with Nellcor Oxismart XL. DESIGN: Cohort study with random allocation of two pulse oximetry devices to two sensor sites. SETTING. University animal research facility. SUBJECTS: Twenty-five adult, anesthetized, ventilated rabbits. INTERVENTIONS:Pneumonia/sepsis was induced by tracheal instillation of E. coli. MEASUREMENTS AND RESULTS:Oxygen saturation was measured by pulse oximetry (SpO(2)) and recorded continuously until death. Arterial oxygen saturation (SaO(2)) was measured hourly by CO oximetry and whenever a difference of >5% between the devices occurred. SpO(2) sensors were positioned at both forelegs and switched hourly. There was no difference in total signal dropout time [median 3.8 min (range 0.4-66.6 min) vs 3.3 min (range 0-94.5 min), Masimo SET vs Oxismart XL]. There were fewer episodes with a false SpO(2) reading [1 (range 0-7) vs 2 (range 0-17)] using the Masimo SET vs the Oxismart XL as verified by CO oximetry; p<0.05. Average bias (SpO(2)-SaO(2)) was significantly different between the two devices, and variability of bias values increased across time with both devices. CONCLUSIONS: Both devices were capable to measure SpO(2) during most of the experimental time in this model of low perfusion and therefore appear to be highly sensitive to pick up a signal; however, low perfusion caused by emerging sepsis may result in inaccurate measurements with both devices. These episodes were less common with the Masimo SET vs the Oxismart XL.
Authors: William W Hay; Donna J Rodden; Shannon M Collins; Diane L Melara; Kathy A Hale; Lucy M Fashaw Journal: J Perinatol Date: 2002 Jul-Aug Impact factor: 2.521
Authors: Helmut D Hummler; Anja Engelmann; Frank Pohlandt; Josef Högel; Axel R Franz Journal: Intensive Care Med Date: 2006-06-30 Impact factor: 17.440