Literature DB >> 7122239

The influence of the purine 2-amino group on DNA conformation and stability. Synthesis and conformational analysis of d[T(2-aminoA)]3.

B L Gaffney, L A Marky, R A Jones.   

Abstract

A self-complementary hexanucleotide consisting of thymidine and 2-amino-deoxyadenosine, d(TA')3, has been synthesized by a solid phase phosphotriester method. Melting studies show that the additional hydrogen bond afforded by the 2-amino group substantially stabilizes the duplex. Moreover, conformational analysis using circular dichroism shows that a salt-induced conformational transition occurs, similar to the B leads to Z transition observed for d(CG)n oligonucleotides.

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Year:  1982        PMID： 7122239      PMCID： PMC320804          DOI： 10.1093/nar/10.14.4351

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  29 in total

1.  Structure and circular dichroism of DNA in concentrated polymer solutions.

Authors:  C F Jordan; L S Lerman; J H Venable
Journal:  Nat New Biol       Date:  1972-03-22

2.  Salt-induced co-operative conformational change of a synthetic DNA: equilibrium and kinetic studies with poly (dG-dC).

Authors:  F M Pohl; T M Jovin
Journal:  J Mol Biol       Date:  1972-06-28       Impact factor: 5.469

3.  Oligonucleotide interactions. 3. Circular dichroism studies of the conformation of deoxyoligonucleotides.

Authors:  C R Cantor; M M Warshaw; H Shapiro
Journal:  Biopolymers       Date:  1970       Impact factor: 2.505

4.  Molecular structure of a left-handed double helical DNA fragment at atomic resolution.

Authors:  A H Wang; G J Quigley; F J Kolpak; J L Crawford; J H van Boom; G van der Marel; A Rich
Journal:  Nature       Date:  1979-12-13       Impact factor: 49.962

5.  Rapid synthesis of oligodeoxyribonucleotides. IV. Improved solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates.

Authors:  M J Gait; M Singh; R C Sheppard; M D Edge; A R Greene; G R Heathcliffe; T C Atkinson; C R Newton; A F Markham
Journal:  Nucleic Acids Res       Date:  1980-03-11       Impact factor: 16.971

6.  A compact form of double-stranded DNA in solution.

Authors:  Y M Evdokimov; A L Platonov; A S Tikhonenko; Y M Varshavsky
Journal:  FEBS Lett       Date:  1972-06-15       Impact factor: 4.124

7.  "Alternating B-DNA" conformation for the oligo(dG-dC) duplex in high-salt solution.

Authors:  D J Patel; L L Canuel; F M Pohl
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

8.  Salt-induced conformational changes of poly(dA-dT).

Authors:  M Vorlícková; J Kypr; V Kleinwächter; E Palecek
Journal:  Nucleic Acids Res       Date:  1980-09-11       Impact factor: 16.971

9.  A comparative X-ray diffraction and circular dichroism study of DNA compact particles formed in water-salt solutions, containing poly(ethylene glycol).

Authors:  Y M Evdokimov; T L Pyatigorskaya; O F Polyvtsev; N M Akimenko; V A Kadykov; D Y Tsvankin; Y M Varshavsky
Journal:  Nucleic Acids Res       Date:  1976-09       Impact factor: 16.971

10.  A transition to a compact form of DNA in polymer solutions.

Authors:  L S Lerman
Journal:  Proc Natl Acad Sci U S A       Date:  1971-08       Impact factor: 11.205
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  12 in total

1.  Evidence for a new Z-type left-handed DNA helix: properties of Z(WC)-DNA.

Authors:  A T Ansevin; A H Wang
Journal:  Nucleic Acids Res       Date:  1990-10-25       Impact factor: 16.971

2.  Consecutive A X T pairs can adopt a left-handed DNA structure.

Authors:  M J McLean; J A Blaho; M W Kilpatrick; R D Wells
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

3.  Thermodynamic studies of base pairing involving 2,6-diaminopurine.

Authors:  C Cheong; I Tinoco; A Chollet
Journal:  Nucleic Acids Res       Date:  1988-06-10       Impact factor: 16.971

4.  Conformation of the synthetic DNA poly(amino2dA-dT) duplex in high-salt and aqueous alcohol solutions.

Authors:  M Vorlícková; J Sági; A Szabolcs; A Szemzö; L Otvös; J Kypr
Journal:  Nucleic Acids Res       Date:  1988-01-11       Impact factor: 16.971

5.  The B----Z transition in two synthetic oligonucleotides: d(C-2-amino-ACGTG) and d(m5CGCAm5CGTGCG) studied by IR, NMR and CD spectroscopies.

Authors:  J A Taboury; S Adam; E Taillandier; J M Neumann; S Tran-Dinh; T Huynh-Dinh; B Langlois d'Estaintot; M Conti; J Igolen
Journal:  Nucleic Acids Res       Date:  1984-08-10       Impact factor: 16.971

6.  Specifically alkylated DNA fragments. Synthesis and physical characterization of d[CGC(O6Me)GCG] and d[CGT(O6Me)GCG].

Authors:  S Kuzmich; L A Marky; R A Jones
Journal:  Nucleic Acids Res       Date:  1983-05-25       Impact factor: 16.971

7.  Molecular structure of deoxycytidyl-3'-methylphosphonate (RP) 5'-deoxyguanidine, d[Cp(CH3)G]. A neutral dinucleotide with Watson-Crick base pairing and a right handed helical twist.

Authors:  F Han; W Watt; D J Duchamp; L Callahan; F J Kézdy; K Agarwal
Journal:  Nucleic Acids Res       Date:  1990-05-11       Impact factor: 16.971

8.  Modified oligonucleotides as alternatives to the synthesis of mixed probes for the screening of cDNA libraries.

Authors:  T Huynh-Dinh; N Duchange; M M Zakin; A Lemarchand; J Igolen
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

9.  Structural interconversion of alternating purine-pyrimidine inverted repeats cloned in supercoiled plasmids.

Authors:  J Klysik; W Zacharias; G Galazka; M Kwinkowski; B Uznanski; A Okruszek
Journal:  Nucleic Acids Res       Date:  1988-07-25       Impact factor: 16.971

10.  B- to Z-DNA transition probed by oligonucleotides containing methylphosphonates.

Authors:  L Callahan; F S Han; W Watt; D Duchamp; F J Kézdy; K Agarwal
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205
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