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Literature DB >> 3387218

Thermodynamic studies of base pairing involving 2,6-diaminopurine.

Abstract

The thermal stabilities of oligodeoxyribonucleotide duplexes containing 2,6-diaminopurine (D) matched with each of the four normal DNA bases were determined by optical melting techniques. Comparison of optical melting curves yielded relative stabilities for the D-containing standard base pairs in an otherwise identical base-pair sequence. The D:T pair was found to be more stable than the A:T pair in dC3DG3:dC3TG3, as stable as the A:T in dCT3DT3G:dCA3TA3G, and less stable than the A:T in dCA3DA3G:dCT7G. The order of stabilities for X:Y in the DNA duplex dCA3XA3G:dCT3YT3G is: (A:T) greater than (T:D) congruent to (D:T) greater than or equal to (T:A) greater than (C:D) congruent to (D:A) congruent to (D:G) greater than or equal to (D:C) congruent to (G:D) congruent to (D:D) greater than or equal to (A:D). Implications of these results for design of DNA oligonucleotide probes are discussed.

Entities: Chemical

Mesh：

Substances：

Year: 1988 PMID： 3387218 PMCID： PMC336721 DOI： 10.1093/nar/16.11.5115

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

30 in total

1. 2-aminoadenine is an adenine substituting for a base in S-2L cyanophage DNA.

Authors: M D Kirnos; I Y Khudyakov; N I Alexandrushkina; B F Vanyushin
Journal: Nature Date: 1977-11-24 Impact factor: 49.962

2. DNA bending at adenine . thymine tracts.

Authors: H S Koo; H M Wu; D M Crothers
Journal: Nature Date: 1986 Apr 10-16 Impact factor: 49.962

3. Cyanophage S-2L contains DNA with 2,6-diaminopurine substituted for adenine.

Authors: I Y Khudyakov; M D Kirnos; N I Alexandrushkina; B F Vanyushin
Journal: Virology Date: 1978-07-01 Impact factor: 3.616

4. The effect of thioketo substitution on uracil-2-aminopurine and uracil-2, 6-diaminopurine interactions in polynucleotides.

Authors: C Janion; K H Scheit
Journal: Biochim Biophys Acta Date: 1976-05-03

5. Poly(2-aminoadenylic acid): interaction with poly(uridylic acid).

Authors: F B Howard; J Frazier; H T Miles
Journal: Biochemistry Date: 1976-08-24 Impact factor: 3.162

6. The stereochemical basis of template function.

Authors: H R Rackwitz; K H Scheit
Journal: Eur J Biochem Date: 1977-01-03

7. Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs.

Authors: M Coll; A H Wang; G A van der Marel; J H van Boom; A Rich
Journal: J Biomol Struct Dyn Date: 1986-10

8. Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch.

Authors: R B Wallace; J Shaffer; R F Murphy; J Bonner; T Hirose; K Itakura
Journal: Nucleic Acids Res Date: 1979-08-10 Impact factor: 16.971

9. Human leukocyte interferon produced by E. coli is biologically active.

Authors: D V Goeddel; E Yelverton; A Ullrich; H L Heyneker; G Miozzari; W Holmes; P H Seeburg; T Dull; L May; N Stebbing; R Crea; S Maeda; R McCandliss; A Sloma; J M Tabor; M Gross; P C Familletti; S Pestka
Journal: Nature Date: 1980-10-02 Impact factor: 49.962

10. Copolymers of adenylic and 2-aminoadenylic acids. Effect of progressive changes in hydrogen bonding and stacking on interaction with poly(uridylic acid).

Authors: M Muraoka; H T Miles; F B Howard
Journal: Biochemistry Date: 1980-05-27 Impact factor: 3.162

19 in total

1. Pyrazolo[3,4-d]pyrimidine nucleic acids: adjustment of dA-dT to dG-dC base pair stability.

Authors: F Seela; G Becher
Journal: Nucleic Acids Res Date: 2001-05-15 Impact factor: 16.971

2. Structural basis for promoter-10 element recognition by the bacterial RNA polymerase σ subunit.

Authors: Andrey Feklistov; Seth A Darst
Journal: Cell Date: 2011-12-01 Impact factor: 41.582

3. Mechanisms of base selection by the Escherichia coli mispaired uracil glycosylase.

Authors: Pingfang Liu; Jacob A Theruvathu; Agus Darwanto; Victoria Valinluck Lao; Tod Pascal; William Goddard; Lawrence C Sowers
Journal: J Biol Chem Date: 2008-01-20 Impact factor: 5.157

4. Structural destabilization of DNA duplexes containing single-base lesions investigated by nanopore measurements.

Authors: Qian Jin; Aaron M Fleming; Yun Ding; Cynthia J Burrows; Henry S White
Journal: Biochemistry Date: 2013-10-31 Impact factor: 3.162

5. Binding specificity and stability of duplexes formed by modified oligonucleotides with a 4096-hexanucleotide microarray.

Authors: E Timofeev; A Mirzabekov
Journal: Nucleic Acids Res Date: 2001-06-15 Impact factor: 16.971

6. Strings of contiguous modified pentanucleotides with increased DNA-binding affinity can be used for DNA sequencing by primer walking.

Authors: T Azhikina; S Veselovskaya; V Myasnikov; V Potapov; O Ermolayeva; E Sverdlov
Journal: Proc Natl Acad Sci U S A Date: 1993-12-15 Impact factor: 11.205

7. Improved templated fluorogenic probes enhance the analysis of closely related pathogenic bacteria by microscopy and flow cytometry.

Authors: Raphael M Franzini; Eric T Kool
Journal: Bioconjug Chem Date: 2011-08-26 Impact factor: 4.774

8. Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing.

Authors: Aaron M Fleming; James G Muller; Adrienne C Dlouhy; Cynthia J Burrows
Journal: J Am Chem Soc Date: 2012-08-29 Impact factor: 15.419

9. Comparative NMR analysis of the decadeoxynucleotide d-(GCATTAATGC)2 and an analogue containing 2-aminoadenine.

Authors: W J Chazin; M Rance; A Chollet; W Leupin
Journal: Nucleic Acids Res Date: 1991-10-25 Impact factor: 16.971

10. Labelling oligonucleotides to high specific activity (I).

Authors: A G Craig; D Nizetic; H Lehrach
Journal: Nucleic Acids Res Date: 1989-06-26 Impact factor: 16.971