| Literature DB >> 6164048 |
E Yelverton, D Leung, P Weck, P W Gray, D V Goeddel.
Abstract
A novel human leukocyte interferon cDNA clone (LeIF B) was identified in a cDNA library prepared using polyadenylated mRNA of a myeloblastoid cell line. The nucleotide sequence of LeIF B differs significantly from other published leukocyte interferon cDNA sequences. An expression plasmid was constructed which directs the synthesis in E. coli of 8 x 10(7) interferon units per liter of culture. LeIF B exhibits markedly different specificities from another bacterially synthesized human leukocyte interferon, LeIF A.Entities:
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Year: 1981 PMID: 6164048 PMCID: PMC327233 DOI: 10.1093/nar/9.3.731
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971