Literature DB >> 31344688

First Cerenkov charge-induction (CCI) TlBr detector for TOF-PET and proton range verification.

Gerard Ariño-Estrada1, Gregory S Mitchell, Hadong Kim, Junwei Du, Sun Il Kwon, Leonard J Cirignano, Kanai S Shah, Simon R Cherry.   

Abstract

Thallium bromide (TlBr) is a semiconductor material and, simultaneously, a good Cerenkov radiator. The performance of a TlBr detector that integrates two different readouts, the charge induction readout and the detection of Cerenkov light, was evaluated. A TlBr detector with dimensions of 4  ×  4  ×  5 mm3, with a monolithic cathode and an anode segmented into strips, was manufactured. One of the bare and polished 4  ×  4 mm2 faces of the detector was coupled to a silicon photomultiplier (SiPM) to read out the Cerenkov light. Simultaneous timing and energy resolutions of  <400 ps full width at half maximum (FWHM) and ~8.5% at 511 keV were measured using the Cerenkov detection and charge induction readouts, respectively. A coincidence time resolution of 330 ps was obtained when selecting Cerenkov events with amplitudes above 70 mV. The combination of both readouts showed the potential to resolve the depth-of-interaction (DOI) positioning, based on the improvement of energy resolution when selecting events with similar electron drift times. This manuscript sets the stage for a new family of semiconductor detectors that combine charge induction readout with the Cerenkov light detection. Such detectors can provide, simultaneously, outstanding timing, energy, and spatial resolution, and will be an excellent fit for applications that require the detection of high-energy gamma photons with high timing accuracy, such as time-of-flight positron emission tomography (TOF-PET) and prompt gamma imaging (PGI) to assess the particle range in hadron therapy.

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Year:  2019        PMID: 31344688      PMCID: PMC8187111          DOI: 10.1088/1361-6560/ab35c4

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  10 in total

1.  Range assessment in particle therapy based on prompt γ-ray timing measurements.

Authors:  Christian Golnik; Fernando Hueso-González; Andreas Müller; Peter Dendooven; Wolfgang Enghardt; Fine Fiedler; Thomas Kormoll; Katja Roemer; Johannes Petzoldt; Andreas Wagner; Guntram Pausch
Journal:  Phys Med Biol       Date:  2014-08-26       Impact factor: 3.609

2.  Towards time-of-flight PET with a semiconductor detector.

Authors:  Gerard Ariño-Estrada; Gregory S Mitchell; Sun Il Kwon; Junwei Du; Hadong Kim; Leonard J Cirignano; Kanai S Shah; Simon R Cherry
Journal:  Phys Med Biol       Date:  2018-02-16       Impact factor: 3.609

3.  A full-scale clinical prototype for proton range verification using prompt gamma-ray spectroscopy.

Authors:  Fernando Hueso-González; Moritz Rabe; Thomas A Ruggieri; Thomas Bortfeld; Joost M Verburg
Journal:  Phys Med Biol       Date:  2018-09-17       Impact factor: 3.609

4.  Hybrid Pixel-Waveform (HPWF) Enabled CdTe Detectors for Small Animal Gamma-Ray Imaging Applications.

Authors:  A Groll; K Kim; H Bhatia; J C Zhang; J H Wang; Z M Shen; L Cai; J Dutta; Q Li; L J Meng
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2016-11-01

5.  Development of TlBr detectors for PET imaging.

Authors:  Gerard Ariño-Estrada; Junwei Du; Hadong Kim; Leonard J Cirignano; Kanai S Shah; Simon R Cherry; Gregory S Mitchell
Journal:  Phys Med Biol       Date:  2018-07-03       Impact factor: 3.609

6.  3D prompt gamma imaging for proton beam range verification.

Authors:  E Draeger; D Mackin; S Peterson; H Chen; S Avery; S Beddar; J C Polf
Journal:  Phys Med Biol       Date:  2018-01-30       Impact factor: 3.609

7.  Energy and coincidence time resolution measurements of CdTe detectors for PET.

Authors:  G Ariño; M Chmeissani; G De Lorenzo; C Puigdengoles; E Cabruja; Y Calderón; M Kolstein; J G Macias-Montero; R Martinez; E Mikhaylova; D Uzun
Journal:  J Instrum       Date:  2013-02       Impact factor: 1.415

8.  New-generation small animal positron emission tomography system for molecular imaging.

Authors:  Shiva Abbaszadeh; Craig S Levin
Journal:  J Med Imaging (Bellingham)       Date:  2017-01-12

9.  First Images of a Three-Layer Compton Telescope Prototype for Treatment Monitoring in Hadron Therapy.

Authors:  Gabriela Llosá; Marco Trovato; John Barrio; Ane Etxebeste; Enrique Muñoz; Carlos Lacasta; Josep F Oliver; Magdalena Rafecas; Carles Solaz; Paola Solevi
Journal:  Front Oncol       Date:  2016-02-02       Impact factor: 6.244

10.  Measurement of mobility and lifetime of electrons and holes in a Schottky CdTe diode.

Authors:  G Ariño-Estrada; M Chmeissani; G de Lorenzo; M Kolstein; C Puigdengoles; J García; E Cabruja
Journal:  J Instrum       Date:  2014-12-01       Impact factor: 1.415

  10 in total
  3 in total

1.  Study of Čerenkov Light Emission in the Semiconductors TlBr and TlCl for TOF-PET.

Authors:  Gerard Ariño-Estrada; Emilie Roncali; Aaron R Selfridge; Junwei Du; Jaroslaw Glodo; Kanai S Shah; Simon R Cherry
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2020-09-17

2.  Energy and electron drift time measurements in a pixel CCI TlBr detector with 1.3 MeV prompt-gammas.

Authors:  Gerard Ariño-Estrada; Hadong Kim; Junwei Du; Leonard J Cirignano; Kanai S Shah; Simon R Cherry
Journal:  Phys Med Biol       Date:  2021-02-02       Impact factor: 4.174

3.  Energy Recovery of Multiple Charge Sharing Events in Room Temperature Semiconductor Pixel Detectors.

Authors:  Antonino Buttacavoli; Gaetano Gerardi; Fabio Principato; Marcello Mirabello; Donato Cascio; Giuseppe Raso; Manuele Bettelli; Andrea Zappettini; Paul Seller; Matthew C Veale; Leonardo Abbene
Journal:  Sensors (Basel)       Date:  2021-05-25       Impact factor: 3.576

  3 in total

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