Literature DB >> 3031618

Minor-groove-modified oligonucleotides: synthesis of decadeoxynucleotides containing hypoxanthine, N2-methylguanine and 3-deazaadenine, and their interactions with restriction endonucleases Bgl II, Sau, 3AI, and Mbo I (Nucleosides and Nucleotides Part 75).

A Ono, T Ueda.   

Abstract

Decadeoxynucleotides containing hypoxanthine, N2-methylguanine, 3-deazaadenine in the recognition sequences of restriction endonucleases Bgl II, Sau 3AI, and Mbo I were synthesized. These decanucleotides modified in the base moieties facing in to the minor groove were strongly resistant to hydrolysis by Bgl II and partially resistant to that of Sau 3AI and Mbo I. The decadeoxynucleotide containing 3-deazaadenine in place of adenine was bound to Bgl II strongly, whereas the nucleotides containing hypoxanthine and N2-methylguanine were bound less tightly.

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Year:  1987        PMID： 3031618      PMCID： PMC340715          DOI： 10.1093/nar/15.7.3059

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  19 in total

1.  A restriction endonuclease from Staphylococcus aureus.

Authors:  J S Sussenbach; C H Monfoort; R Schiphof; E E Stobberingh
Journal:  Nucleic Acids Res       Date:  1976-11       Impact factor: 16.971

2.  The use of nuclease P1 in sequence analysis of end group labeled RNA.

Authors:  M Silberklang; A M Gillum; U L RajBhandary
Journal:  Nucleic Acids Res       Date:  1977-12       Impact factor: 16.971

3.  Two sequence-specific endonucleases from Moraxella bovis.

Authors:  R E Gelinas; P A Myers; R J Roberts
Journal:  J Mol Biol       Date:  1977-07       Impact factor: 5.469

4.  Synthesis of decadeoxyribonucleotides containing N6-methyladenine, N4-methylcytosine, and 5-methylcytosine: recognition and cleavage by restriction endonucleases (nucleosides and nucleotides part 74).

Authors:  A Ono; T Ueda
Journal:  Nucleic Acids Res       Date:  1987-01-12       Impact factor: 16.971

5.  Role of the 2-amino group of deoxyguanosine in sequence recognition by EcoRI restriction and modification enzymes.

Authors:  P Modrich; R A Rubin
Journal:  J Biol Chem       Date:  1977-10-25       Impact factor: 5.157

6.  Biochemical and genetic properties of site-specific restriction endonucleases in Bacillus globigii.

Authors:  C H Duncan; G A Wilson; F E Young
Journal:  J Bacteriol       Date:  1978-04       Impact factor: 3.490

7.  DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping.

Authors:  E Jay; R Bambara; R Padmanabhan; R Wu
Journal:  Nucleic Acids Res       Date:  1974-03       Impact factor: 16.971

8.  Simplications in the synthesis of short oligonucleotide blocks.

Authors:  C Broka; T Hozumi; R Arentzen; K Itakura
Journal:  Nucleic Acids Res       Date:  1980-11-25       Impact factor: 16.971

9.  Solid-phase synthesis of polynucleotides. IV. Usage of polystyrene resins for the synthesis of polydeoxyribonucleotides by the phosphostriester method.

Authors:  K Miyoshi; R Arentzen; T Huang; K Itakura
Journal:  Nucleic Acids Res       Date:  1980-11-25       Impact factor: 16.971

10.  Nucleotides. VI. Syntheses and spectral properties of some deazaadenylyl-deazaadenosines (dinucleoside monophosphates with unusual CD-spectrum) and closely related dinucleoside monophosphates.

Authors:  Y Mizuno; S Kitano; A Nomura
Journal:  Nucleic Acids Res       Date:  1975-12       Impact factor: 16.971
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  8 in total

1.  DNA containing the base analogue 2-aminoadenine: preparation, use as hybridization probes and cleavage by restriction endonucleases.

Authors:  A Chollet; E Kawashima
Journal:  Nucleic Acids Res       Date:  1988-01-11       Impact factor: 16.971

2.  7-Deaza-2'-deoxyadenosine and 3-deaza-2'-deoxyadenosine replacing dA within d(A6)-tracts: differential bending at 3'- and 5'-junctions of d(A6).d(T6) and B-DNA.

Authors:  F Seela; T Grein
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

3.  Molecular recognition in the minor groove of the DNA helix. Studies on the synthesis of oligonucleotides and polynucleotides containing 3-deaza-2'-deoxyadenosine. Interaction of the oligonucleotides with the restriction endonuclease EcoRV.

Authors:  R Cosstick; X Li; D K Tuli; D M Williams; B A Connolly; P C Newman
Journal:  Nucleic Acids Res       Date:  1990-08-25       Impact factor: 16.971

4.  Analysis of the recognition mechanism involved in the EcoRV catalyzed cleavage of DNA using modified oligodeoxynucleotides.

Authors:  A Fliess; H Wolfes; F Seela; A Pingoud
Journal:  Nucleic Acids Res       Date:  1988-12-23       Impact factor: 16.971

5.  Structure and Base Pairing Properties of a Replicable Nonpolar Isostere for Deoxyadenosine.

Authors:  Kevin M Guckian; Juan C Morales; Eric T Kool
Journal:  J Org Chem       Date:  1998       Impact factor: 4.354

6.  Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base pairs.

Authors:  C Lever; X Li; R Cosstick; S Ebel; T Brown
Journal:  Nucleic Acids Res       Date:  1993-04-25       Impact factor: 16.971

7.  Synthesis of decadeoxyribonucleotides containing 5-modified uracils and their interactions with restriction endonucleases Bgl II, Sau 3AI and Mbo I (nucleosides and nucleotides 82).

Authors:  T Hayakawa; A Ono; T Ueda
Journal:  Nucleic Acids Res       Date:  1988-06-10       Impact factor: 16.971

8.  Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base.

Authors:  Ke Wang; Sandra Stringfellow; Shiming Dong; Yugao Jiao; Hongtao Yu
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2002-10       Impact factor: 4.098
  8 in total

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