Ya-Jun Ma1, Yanchun Zhu1, Xing Lu1, Michael Carl2, Eric Y Chang1,3, Jiang Du1. 1. Department of Radiology, University of California, San Diego, California, USA. 2. GE Healthcare, San Diego, California, USA. 3. Radiology Service, VA San Diego Healthcare System, San Diego, California, USA.
Abstract
PURPOSE: To investigate high contrast imaging of short T2 tissues with a three-dimensional double adiabatic inversion recovery prepared ultrashort echo time Cones (3D DIR-UTE-Cones) sequence. METHODS: The sequence used two sequential adiabatic inversion pulses to suppress signals from long T2 tissues, followed by multispoke UTE acquisition to detect signals from short T2 tissues. The two adiabatic inversion pulses are identical with a center frequency located at the water peak, but the spectral width is broad enough to cover both water and fat frequencies. The feasibility of this technique was demonstrated through numerical simulation and phantom studies. Finally, DIR-UTE-Cones was applied to three healthy volunteers to image cortical bone, patellar tendon, and Achilles tendon. T2* was also measured via single-component exponential fitting. RESULTS: Numerical simulation suggests that the DIR technique provides perfect nulling of muscle and fat as well as efficient suppression of other long T2 tissues with T1 values between fat and water or those above water. Excellent image contrast can be achieved with DIR-UTE-Cones for the short T2 tissues, with fitted T2* values of 0.28-0.38 ms for cortical bone, 0.56 ± 0.07 ms for the patella tendon, and 0.45 ± 0.06 ms for the Achilles tendon, respectively. CONCLUSION: The 3D DIR-UTE-Cones sequence provides robust suppression of long T2 tissues and allows selective imaging as well as T2* measurement of short T2 tissues such as cortical bone, patellar tendon, and the Achilles tendon. Magn Reson Med 79:2555-2563, 2018.
PURPOSE: To investigate high contrast imaging of short T2 tissues with a three-dimensional double adiabatic inversion recovery prepared ultrashort echo time Cones (3D DIR-UTE-Cones) sequence. METHODS: The sequence used two sequential adiabatic inversion pulses to suppress signals from long T2 tissues, followed by multispoke UTE acquisition to detect signals from short T2 tissues. The two adiabatic inversion pulses are identical with a center frequency located at the water peak, but the spectral width is broad enough to cover both water and fat frequencies. The feasibility of this technique was demonstrated through numerical simulation and phantom studies. Finally, DIR-UTE-Cones was applied to three healthy volunteers to image cortical bone, patellar tendon, and Achilles tendon. T2* was also measured via single-component exponential fitting. RESULTS: Numerical simulation suggests that the DIR technique provides perfect nulling of muscle and fat as well as efficient suppression of other long T2 tissues with T1 values between fat and water or those above water. Excellent image contrast can be achieved with DIR-UTE-Cones for the short T2 tissues, with fitted T2* values of 0.28-0.38 ms for cortical bone, 0.56 ± 0.07 ms for the patella tendon, and 0.45 ± 0.06 ms for the Achilles tendon, respectively. CONCLUSION: The 3D DIR-UTE-Cones sequence provides robust suppression of long T2 tissues and allows selective imaging as well as T2* measurement of short T2 tissues such as cortical bone, patellar tendon, and the Achilles tendon. Magn Reson Med 79:2555-2563, 2018.
Authors: Garry E Gold; Eric Han; Jeff Stainsby; Graham Wright; Jean Brittain; Christopher Beaulieu Journal: AJR Am J Roentgenol Date: 2004-08 Impact factor: 3.959
Authors: Jiang Du; Michael Carl; Mark Bydder; Atsushi Takahashi; Christine B Chung; Graeme M Bydder Journal: J Magn Reson Date: 2010-09-25 Impact factor: 2.229
Authors: Peder E Z Larson; Paul T Gurney; Krishna Nayak; Garry E Gold; John M Pauly; Dwight G Nishimura Journal: Magn Reson Med Date: 2006-07 Impact factor: 4.668
Authors: Ya-Jun Ma; Xing Lu; Michael Carl; Yanchun Zhu; Nikolaus M Szeverenyi; Graeme M Bydder; Eric Y Chang; Jiang Du Journal: Magn Reson Med Date: 2018-01-03 Impact factor: 4.668
Authors: Xing Lu; Yajun Ma; Eric Y Chang; Qun He; Adam Searleman; Annette von Drygalski; Jiang Du Journal: Magn Reson Med Date: 2018-01-04 Impact factor: 4.668
Authors: Behnam Namiranian; Saeed Jerban; Yajun Ma; Erik W Dorthe; Amir Masoud-Afsahi; Jonathan Wong; Zhao Wei; Yanjun Chen; Darryl D'Lima; Eric Y Chang; Jiang Du Journal: J Biomech Date: 2020-10-24 Impact factor: 2.712
Authors: Ya-Jun Ma; Wei Zhao; Lidi Wan; Tan Guo; Adam Searleman; Hyungseok Jang; Eric Y Chang; Jiang Du Journal: Magn Reson Med Date: 2018-11-16 Impact factor: 4.668
Authors: Hyungseok Jang; Zhao Wei; Mei Wu; Ya-Jun Ma; Eric Y Chang; Jody Corey-Bloom; Jiang Du Journal: Magn Reson Med Date: 2019-11-20 Impact factor: 4.668