| Literature DB >> 2762114 |
J A Armour1, Z Wong, V Wilson, N J Royle, A J Jeffreys.
Abstract
We present DNA sequences flanking cloned hypervariable human minisatellites. In addition to providing confirmatory evidence that minisatellites cluster with other tandem repeats, these flanking sequences contain a high frequency of interspersed repetitive elements. These elements include a retroviral LTR-like sequence, from which one of the minisatellites appears to have expanded, and a recently described short interspersed repeat. We present our own findings concerning this element, in particular that those examples studied do not show significant evolutionary conservation, despite suggestions that the element may have a cis-acting function.Entities:
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Year: 1989 PMID: 2762114 PMCID: PMC318084 DOI: 10.1093/nar/17.13.4925
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971