Literature DB >> 3856104

Hypervariable 'minisatellite' regions in human DNA.

A J Jeffreys, V Wilson, S L Thein.   

Abstract

The human genome contains many dispersed tandem-repetitive 'minisatellite' regions detected via a shared 10-15-base pair 'core' sequence similar to the generalized recombination signal (chi) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite. A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA 'fingerprint' of general use in human genetic analysis.

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Year:  1985        PMID： 3856104     DOI： 10.1038/314067a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  605 in total

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Authors:  P R LaFayette; K E Eriksson; J F Dean
Journal:  Plant Mol Biol       Date:  1999-05       Impact factor: 4.076

2.  Meiotic recombination and flanking marker exchange at the highly unstable human minisatellite CEB1 (D2S90).

Authors:  J Buard; A C Shone; A J Jeffreys
Journal:  Am J Hum Genet       Date:  2000-06-26       Impact factor: 11.025

3.  The 10q25 neocentromere and its inactive progenitor have identical primary nucleotide sequence: further evidence for epigenetic modification.

Authors:  A E Barry; M Bateman; E V Howman; M R Cancilla; K M Tainton; D V Irvine; R Saffery; K H Choo
Journal:  Genome Res       Date:  2000-06       Impact factor: 9.043

4.  Comparative sequence analysis of human minisatellites showing meiotic repeat instability.

Authors:  J Murray; J Buard; D L Neil; E Yeramian; K Tamaki; C Hollies; A J Jeffreys
Journal:  Genome Res       Date:  1999-02       Impact factor: 9.043

5.  2001 ASHG Presidential Address. On black boxes and storytellers: lessons learned in human genetics.

Authors:  Huntington F Willard
Journal:  Am J Hum Genet       Date:  2002-01-04       Impact factor: 11.025

6.  Cell culture forensics.

Authors:  S J O'Brien
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-03       Impact factor: 11.205

7.  DNA flow cytometric quantification and DNA polymorphism analysis in the case of a complete mole with a coexisting fetus.

Authors:  M Hirose; T Kimura; N Mitsuno; K Wakuda; K Takakura; J Fujita; Y Noda
Journal:  J Assist Reprod Genet       Date:  1999-05       Impact factor: 3.412

8.  Sp1 binds to the precise locus of end processing within the terminal repeats of Epstein-Barr virus DNA.

Authors:  R Sun; T A Spain; S F Lin; G Miller
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

9.  DNA fingerprinting with the oligonucleotide probe (CAC)5/(GTG)5: somatic stability and germline mutations.

Authors:  P Nürnberg; L Roewer; H Neitzel; K Sperling; A Pöpperl; J Hundrieser; H Pöche; C Epplen; H Zischler; J T Epplen
Journal:  Hum Genet       Date:  1989-12       Impact factor: 4.132

10.  Nucleotide sequence and genomic organization of bird minisatellites.

Authors:  U B Gyllensten; S Jakobsson; H Temrin; A C Wilson
Journal:  Nucleic Acids Res       Date:  1989-03-25       Impact factor: 16.971
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