Literature DB >> 26756395

Multicenter clinical trial of the Nucleus Hybrid S8 cochlear implant: Final outcomes.

Bruce J Gantz1, Camille Dunn1, Jacob Oleson2, Marlan Hansen1, Aaron Parkinson3,4, Christopher Turner5.   

Abstract

OBJECTIVES/HYPOTHESIS: The concept of expanding electrical speech processing to those with more residual acoustic hearing with a less-invasive shorter cochlear implant (CI) has been ongoing since 1999. A multicenter study of the Nucleus Hybrid S8 CI took place between 2002 and 2011. This report describes the final outcomes of this clinical trial. STUDY
DESIGN: Multicenter, longitudinal, single-subject design.
METHODS: Eighty-seven subjects received a Nucleus Hybrid S8 CI in their poorer ear. Speech perception in quiet (Consonant-Nucleus-Consonant [CNC] words) and in noise (Bamford-Kowal-Bench Sentences-In-Noise [BKB-SIN]) were collected pre- and postoperatively at 3, 6, and 12 months. Subjective questionnaire data using the Abbreviated Profile for Hearing Aid Benefit (APHAB) were also collected.
RESULTS: Some level of hearing preservation was accomplished in 98% subjects, with 90% maintaining a functional low-frequency pure-tone average (LFPTA) at initial activation. By 12 months, five subjects had total hearing loss, and 80% of subjects maintained functional hearing. CNC words demonstrated that 82.5% and 87.5% of subjects had significant improvements in the hybrid and combined conditions, respectively. The majority had improvements with BKB-SIN. Results also indicated that as long as subjects maintained at least a severe LFPTA, there was significant improvement in speech understanding. Furthermore, all subjects reported positive improvements in hearing in three of the four subscales of the APHAB.
CONCLUSIONS: The concept of hybrid speech processing has significant advantages for subjects with residual low-frequency hearing. In this study, the Nucleus Hybrid S8 provided improved word understanding in quiet and noise. Additionally, there appears to be stability of the residual hearing after initial activation of the device. LEVEL OF EVIDENCE: 2c.
© 2016 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Hybrid cochlear implant; acoustic plus electric; hearing preservation; short electrode; speech perception

Mesh:

Year:  2016        PMID: 26756395      PMCID: PMC4803613          DOI: 10.1002/lary.25572

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  28 in total

1.  Residual speech recognition and cochlear implant performance: effects of implantation criteria.

Authors:  J T Rubinstein; W S Parkinson; R S Tyler; B J Gantz
Journal:  Am J Otol       Date:  1999-07

2.  Preservation of hearing in cochlear implant surgery: advantages of combined electrical and acoustical speech processing.

Authors:  Bruce J Gantz; Christopher Turner; Kate E Gfeller; Mary W Lowder
Journal:  Laryngoscope       Date:  2005-05       Impact factor: 3.325

3.  Music perception with cochlear implants and residual hearing.

Authors:  Kate E Gfeller; Carol Olszewski; Christopher Turner; Bruce Gantz; Jacob Oleson
Journal:  Audiol Neurootol       Date:  2006-10-06       Impact factor: 1.854

4.  Acoustic plus electric speech processing: preliminary results of a multicenter clinical trial of the Iowa/Nucleus Hybrid implant.

Authors:  Bruce J Gantz; Christopher Turner; Kate E Gfeller
Journal:  Audiol Neurootol       Date:  2006-10-06       Impact factor: 1.854

Review 5.  Combined acoustic and electric hearing: preserving residual acoustic hearing.

Authors:  Christopher W Turner; Lina A J Reiss; Bruce J Gantz
Journal:  Hear Res       Date:  2007-11-29       Impact factor: 3.208

6.  The effects of hearing loss on the contribution of high- and low-frequency speech information to speech understanding. II. Sloping hearing loss.

Authors:  Benjamin W Y Hornsby; Todd A Ricketts
Journal:  J Acoust Soc Am       Date:  2006-03       Impact factor: 1.840

7.  Hybrid 10 clinical trial: preliminary results.

Authors:  Bruce J Gantz; Marlan R Hansen; Christopher W Turner; Jacob J Oleson; Lina A Reiss; Aaron J Parkinson
Journal:  Audiol Neurootol       Date:  2009-04-22       Impact factor: 1.854

8.  Hearing conservation surgery using the Hybrid-L electrode. Results from the first clinical trial at the Medical University of Hannover.

Authors:  Thomas Lenarz; Timo Stöver; Andreas Buechner; Anke Lesinski-Schiedat; Jim Patrick; Joerg Pesch
Journal:  Audiol Neurootol       Date:  2009-04-22       Impact factor: 1.854

9.  Changes in pitch with a cochlear implant over time.

Authors:  Lina A J Reiss; Christopher W Turner; Sheryl R Erenberg; Bruce J Gantz
Journal:  J Assoc Res Otolaryngol       Date:  2007-03-09

10.  Hearing preservation surgery: psychophysical estimates of cochlear damage in recipients of a short electrode array.

Authors:  René H Gifford; Michael F Dorman; Anthony J Spahr; Sid P Bacon; Henryk Skarzynski; Artur Lorens
Journal:  J Acoust Soc Am       Date:  2008-10       Impact factor: 2.482

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  48 in total

1.  Using Neural Response Telemetry to Monitor Physiological Responses to Acoustic Stimulation in Hybrid Cochlear Implant Users.

Authors:  Paul J Abbas; Viral D Tejani; Rachel A Scheperle; Carolyn J Brown
Journal:  Ear Hear       Date:  2017 Jul/Aug       Impact factor: 3.570

2.  Postoperative Electrocochleography from Hybrid Cochlear Implant users: An Alternative Analysis Procedure.

Authors:  Jeong-Seo Kim; Viral D Tejani; Paul J Abbas; Carolyn J Brown
Journal:  Hear Res       Date:  2018-10-29       Impact factor: 3.208

3.  Hybrid Music Perception Outcomes: Implications for Melody and Timbre Recognition in Cochlear Implant Recipients.

Authors:  Aaron J Parkinson; Jay T Rubinstein; Ward R Drennan; Christa Dodson; Kaibao Nie
Journal:  Otol Neurotol       Date:  2019-03       Impact factor: 2.311

4.  Bilateral Cochlear Implants Using Two Electrode Lengths in Infants With Profound Deafness.

Authors:  Camille C Dunn; Elizabeth A Walker; Stephanie Gogel; Tanya Van Voorst; Marlan Hansen; Bruce J Gantz
Journal:  Otol Neurotol       Date:  2019-03       Impact factor: 2.311

5.  Outcomes of Adolescents With a Short Electrode Cochlear Implant With Preserved Residual Hearing.

Authors:  Bruce J Gantz; Camille Dunn; Elizabeth Walker; Tanya Van Voorst; Stephanie Gogel; Marlan Hansen
Journal:  Otol Neurotol       Date:  2016-02       Impact factor: 2.311

6.  Insertion characteristics and placement of the Mid-Scala electrode array in human temporal bones using detailed cone beam computed tomography.

Authors:  Aarno Dietz; Dzemal Gazibegovic; Jyrki Tervaniemi; Veli-Matti Vartiainen; Heikki Löppönen
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-05-19       Impact factor: 2.503

7.  Minimum Reporting Standards for Adult Cochlear Implantation.

Authors:  Oliver F Adunka; Bruce J Gantz; Camille Dunn; Richard K Gurgel; Craig A Buchman
Journal:  Otolaryngol Head Neck Surg       Date:  2018-03-20       Impact factor: 3.497

Review 8.  Electrical stimulation of cranial nerves in cognition and disease.

Authors:  Devin Adair; Dennis Truong; Zeinab Esmaeilpour; Nigel Gebodh; Helen Borges; Libby Ho; J Douglas Bremner; Bashar W Badran; Vitaly Napadow; Vincent P Clark; Marom Bikson
Journal:  Brain Stimul       Date:  2020-02-23       Impact factor: 8.955

9.  Delayed changes in auditory status in cochlear implant users with preserved acoustic hearing.

Authors:  Rachel A Scheperle; Viral D Tejani; Julia K Omtvedt; Carolyn J Brown; Paul J Abbas; Marlan R Hansen; Bruce J Gantz; Jacob J Oleson; Marie V Ozanne
Journal:  Hear Res       Date:  2017-04-12       Impact factor: 3.208

10.  Effect of Scala Tympani Height on Insertion Depth of Straight Cochlear Implant Electrodes.

Authors:  William G Morrel; Jourdan T Holder; Benoit M Dawant; Jack H Noble; Robert F Labadie
Journal:  Otolaryngol Head Neck Surg       Date:  2020-02-25       Impact factor: 3.497

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