Literature DB >> 26626939

Induced Pluripotency and Epigenetic Reprogramming.

Konrad Hochedlinger1, Rudolf Jaenisch2.   

Abstract

Induced pluripotency defines the process by which somatic cells are converted into induced pluripotent stem cells (iPSCs) upon overexpression of a small set of transcription factors. In this article, we put transcription factor-induced pluripotency into a historical context, review current methods to generate iPSCs, and discuss mechanistic insights that have been gained into the process of reprogramming. In addition, we focus on potential therapeutic applications of induced pluripotency and emerging technologies to efficiently engineer the genomes of human pluripotent cells for scientific and therapeutic purposes.
Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26626939      PMCID： PMC4665075          DOI： 10.1101/cshperspect.a019448

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Biol        ISSN： 1943-0264            Impact factor:   9.708


  165 in total

1.  Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.

Authors:  T Wakayama; V Tabar; I Rodriguez; A C Perry; L Studer; P Mombaerts
Journal:  Science       Date:  2001-04-27       Impact factor: 47.728

2.  X-Chromosome inactivation in cloned mouse embryos.

Authors:  K Eggan; H Akutsu; K Hochedlinger; W Rideout; R Yanagimachi; R Jaenisch
Journal:  Science       Date:  2000-11-24       Impact factor: 47.728

Review 3.  Epigenetic reprogramming in mammalian development.

Authors:  W Reik; W Dean; J Walter
Journal:  Science       Date:  2001-08-10       Impact factor: 47.728

4.  Pluripotency of reprogrammed somatic genomes in embryonic stem hybrid cells.

Authors:  Masako Tada; Asuka Morizane; Hironobu Kimura; Hiroshi Kawasaki; Justin F X Ainscough; Yoshiki Sasai; Norio Nakatsuji; Takashi Tada
Journal:  Dev Dyn       Date:  2003-08       Impact factor: 3.780

5.  MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS.

Authors:  L J KLEINSMITH; G B PIERCE
Journal:  Cancer Res       Date:  1964-10       Impact factor: 12.701

6.  The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles.

Authors:  J B GURDON
Journal:  J Embryol Exp Morphol       Date:  1962-12

7.  Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei.

Authors:  M J Munsie; A E Michalska; C M O'Brien; A O Trounson; M F Pera; P S Mountford
Journal:  Curr Biol       Date:  2000-08-24       Impact factor: 10.834

8.  Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation.

Authors:  K Eggan; H Akutsu; J Loring; L Jackson-Grusby; M Klemm; W M Rideout; R Yanagimachi; R Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-01       Impact factor: 11.205

9.  Monoclonal mice generated by nuclear transfer from mature B and T donor cells.

Authors:  Konrad Hochedlinger; Rudolf Jaenisch
Journal:  Nature       Date:  2002-02-10       Impact factor: 49.962

10.  Mice cloned from olfactory sensory neurons.

Authors:  Kevin Eggan; Kristin Baldwin; Michael Tackett; Joseph Osborne; Joseph Gogos; Andrew Chess; Richard Axel; Rudolf Jaenisch
Journal:  Nature       Date:  2004-02-15       Impact factor: 49.962
View more
  32 in total

Review 1.  Chromatin accessibility dynamics during cell fate reprogramming.

Authors:  Dongwei Li; Xiaodong Shu; Ping Zhu; Duanqing Pei
Journal:  EMBO Rep       Date:  2021-01-22       Impact factor: 8.807

Review 2.  Maintenance of Epigenetic Information.

Authors:  Geneviève Almouzni; Howard Cedar
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-05-02       Impact factor: 10.005

Review 3.  Reprogramming of germ cells into pluripotency.

Authors:  Yoichi Sekita; Toshinobu Nakamura; Tohru Kimura
Journal:  World J Stem Cells       Date:  2016-08-26       Impact factor: 5.326

4.  Purging Exhausted Virus-Specific CD8 T Cell Phenotypes by Somatic Cell Reprogramming.

Authors:  Joshua Chan; Patrick Y Kim; Emiko Kranz; Yoshiko Nagaoka; YooJin Lee; Jing Wen; Heidi J Elsaesser; Meng Qin; David G Brooks; Gene-Errol Ringpis; Irvin S Y Chen; Masakazu Kamata
Journal:  AIDS Res Hum Retroviruses       Date:  2017-11       Impact factor: 2.205

5.  Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas.

Authors:  Haiting Ma; Katherine J Wert; Dmitry Shvartsman; Douglas A Melton; Rudolf Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  2018-03-29       Impact factor: 11.205

Review 6.  Emerging roles of the histone chaperone CAF-1 in cellular plasticity.

Authors:  Sihem Cheloufi; Konrad Hochedlinger
Journal:  Curr Opin Genet Dev       Date:  2017-07-07       Impact factor: 5.578

Review 7.  Cellular trajectories and molecular mechanisms of iPSC reprogramming.

Authors:  Effie Apostolou; Matthias Stadtfeld
Journal:  Curr Opin Genet Dev       Date:  2018-06-17       Impact factor: 5.578

Review 8.  Finding MyoD and lessons learned along the way.

Authors:  Andrew B Lassar
Journal:  Semin Cell Dev Biol       Date:  2017-11-01       Impact factor: 7.727

Review 9.  Epigenetic aberrations in human pluripotent stem cells.

Authors:  Shiran Bar; Nissim Benvenisty
Journal:  EMBO J       Date:  2019-05-14       Impact factor: 11.598

10.  Epigenetic regulation of REX1 expression and chromatin binding specificity by HMGNs.

Authors:  Shaofei Zhang; Tao Deng; Wei Tang; Bing He; Takashi Furusawa; Stefan Ambs; Michael Bustin
Journal:  Nucleic Acids Res       Date:  2019-05-21       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.