Literature DB >> 11326103

Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.

T Wakayama1, V Tabar, I Rodriguez, A C Perry, L Studer, P Mombaerts.   

Abstract

Embryonic stem (ES) cells are fully pluripotent in that they can differentiate into all cell types, including gametes. We have derived 35 ES cell lines via nuclear transfer (ntES cell lines) from adult mouse somatic cells of inbred, hybrid, and mutant strains. ntES cells contributed to an extensive variety of cell types, including dopaminergic and serotonergic neurons in vitro and germ cells in vivo. Cloning by transfer of ntES cell nuclei could result in normal development of fertile adults. These studies demonstrate the full pluripotency of ntES cells.

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Year:  2001        PMID: 11326103     DOI: 10.1126/science.1059399

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  109 in total

1.  From intestine to muscle: nuclear reprogramming through defective cloned embryos.

Authors:  J A Byrne; S Simonsson; J B Gurdon
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-23       Impact factor: 11.205

Review 2.  Nuclear reprogramming and stem cell creation.

Authors:  J B Gurdon; J A Byrne; S Simonsson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-14       Impact factor: 11.205

Review 3.  Immunogenicity and allogenicity: a challenge of stem cell therapy.

Authors:  Dominique Charron; Caroline Suberbielle-Boissel; Reem Al-Daccak
Journal:  J Cardiovasc Transl Res       Date:  2008-09-26       Impact factor: 4.132

Review 4.  The challenge of immunogenicity in the quest for induced pluripotency.

Authors:  Paul J Fairchild
Journal:  Nat Rev Immunol       Date:  2010-12       Impact factor: 53.106

Review 5.  Induced pluripotency: history, mechanisms, and applications.

Authors:  Matthias Stadtfeld; Konrad Hochedlinger
Journal:  Genes Dev       Date:  2010-10-15       Impact factor: 11.361

Review 6.  A transcriptional roadmap to the induction of pluripotency in somatic cells.

Authors:  Ying Wang; Nancy Mah; Alessandro Prigione; Katharina Wolfrum; Miguel A Andrade-Navarro; James Adjaye
Journal:  Stem Cell Rev Rep       Date:  2010-06       Impact factor: 5.739

Review 7.  Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications.

Authors:  Shogo Matoba; Yi Zhang
Journal:  Cell Stem Cell       Date:  2018-07-19       Impact factor: 24.633

Review 8.  Mechanisms underlying the formation of induced pluripotent stem cells.

Authors:  Federico González; Danwei Huangfu
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2015-09-18       Impact factor: 5.814

9.  Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance.

Authors:  Alexandre Fort; Kosuke Hashimoto; Daisuke Yamada; Md Salimullah; Chaman A Keya; Alka Saxena; Alessandro Bonetti; Irina Voineagu; Nicolas Bertin; Anton Kratz; Yukihiko Noro; Chee-Hong Wong; Michiel de Hoon; Robin Andersson; Albin Sandelin; Harukazu Suzuki; Chia-Lin Wei; Haruhiko Koseki; Yuki Hasegawa; Alistair R R Forrest; Piero Carninci
Journal:  Nat Genet       Date:  2014-04-28       Impact factor: 38.330

Review 10.  Stem cell potency and the ability to contribute to chimeric organisms.

Authors:  Irina Polejaeva; Shoukhrat Mitalipov
Journal:  Reproduction       Date:  2013-03-07       Impact factor: 3.906

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