High-resolution, anamorphic, adaptive small-animal SPECT imaging with silicon double-sided strip detectors.

We are developing a prototype gamma-ray imaging system that consists of two sets of movable, keel-edged copper-tungsten blades configured as crossed slits. These apertures can be positioned independently between the object and detector, producing an anamorphic image in which the axial and transaxial magnifications are not constrained to be equal. The detector is a 60 mm × 60 mm, millimeter thick, one-megapixel silicon double-sided strip detector. The flexible nature of this system allows the application of adaptive imaging techniques. We will discuss system details, calibration and acquisition methods, and our progress towards biological imaging applications.