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Literature DB >> 21218137

System Integration of FastSPECT III, a Dedicated SPECT Rodent-Brain Imager Based on BazookaSPECT Detector Technology.

Brian W Miller¹, Lars R Furenlid, Stephen K Moore, H Bradford Barber, Vivek V Nagarkar, Harrison H Barrett.

Abstract

FastSPECT III is a stationary, single-photon emission computed tomography (SPECT) imager designed specifically for imaging and studying neurological pathologies in rodent brain, including Alzheimer's and Parkinsons's disease. Twenty independent BazookaSPECT [1] gamma-ray detectors acquire projections of a spherical field of view with pinholes selected for desired resolution and sensitivity. Each BazookaSPECT detector comprises a columnar CsI(Tl) scintillator, image-intensifier, optical lens, and fast-frame-rate CCD camera. Data stream back to processing computers via firewire interfaces, and heavy use of graphics processing units (GPUs) ensures that each frame of data is processed in real time to extract the images of individual gamma-ray events. Details of the system design, imaging aperture fabrication methods, and preliminary projection images are presented.

Entities: Chemical Disease Species

Year: 2009 PMID： 21218137 PMCID： PMC3017366 DOI： 10.1109/NSSMIC.2009.5401924

Source DB: PubMed Journal: IEEE Nucl Sci Symp Conf Rec (1997) ISSN： 1095-7863

8 in total

1. FastSPECT II: A Second-Generation High-Resolution Dynamic SPECT Imager.

Authors: Lars R Furenlid; Donald W Wilson; Yi-Chun Chen; Hyunki Kim; Philip J Pietraski; Michael J Crawford; Harrison H Barrett
Journal: IEEE Trans Nucl Sci Date: 2004-06 Impact factor: 1.679

2. A Task-Based Approach to Adaptive and Multimodality Imaging: Computation techniques are proposed for figures-of-merit to establish feasibility and optimize use of multiple imaging systems for disease diagnosis and treatment-monitoring.

Authors: Eric Clarkson; Matthew A Kupinski; Harrison H Barrett; Lars Furenlid
Journal: Proc IEEE Inst Electr Electron Eng Date: 2008-03 Impact factor: 10.961

3. Adaptive SPECT.

Authors: Harrison H Barrett; Lars R Furenlid; Melanie Freed; Jacob Y Hesterman; Matthew A Kupinski; Eric Clarkson; Meredith K Whitaker
Journal: IEEE Trans Med Imaging Date: 2008-06 Impact factor: 10.048

4. A prototype instrument for single pinhole small animal adaptive SPECT imaging.

Authors: Melanie Freed; Matthew A Kupinski; Lars R Furenlid; Donald W Wilson; Harrison H Barrett
Journal: Med Phys Date: 2008-05 Impact factor: 4.071

5. Recent advances in BazookaSPECT: Real-time data processing and the development of a gamma-ray microscope.

Authors: Brian W Miller; Harrison H Barrett; Lars R Furenlid; H Bradford Barber; Robert J Hunter
Journal: Nucl Instrum Methods Phys Res A Date: 2008-06-11 Impact factor: 1.455

6. SemiSPECT: a small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays.

Authors: Hyunki Kim; Lars R Furenlid; Michael J Crawford; Donald W Wilson; H Bradford Barber; Todd E Peterson; William C J Hunter; Zhonglin Liu; James M Woolfenden; Harrison H Barrett
Journal: Med Phys Date: 2006-02 Impact factor: 4.071

7. Novel Applications of Rapid Prototyping in Gamma-ray and X-ray Imaging.

Authors: Brian W Miller; Jared W Moore; Michael E Gehm; Lars R Furenlid; Harrison H Barrett
Journal: IEEE Nucl Sci Symp Conf Rec (1997) Date: 2009-10-24

8. Maximum-Likelihood Methods for Processing Signals From Gamma-Ray Detectors.

Authors: Harrison H Barrett; William C J Hunter; Brian William Miller; Stephen K Moore; Yichun Chen; Lars R Furenlid
Journal: IEEE Trans Nucl Sci Date: 2009-06-01 Impact factor: 1.679

8 in total

16 in total

Review 1. Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging.

Authors: Karen Van Audenhaege; Roel Van Holen; Stefaan Vandenberghe; Christian Vanhove; Scott D Metzler; Stephen C Moore
Journal: Med Phys Date: 2015-08 Impact factor: 4.071

2. SPEM: a state-of-the-art instrument for high resolution molecular imaging of small animal organs.

Authors: Marilia Alves dos Reis; Jorge Mejia; Ilza Rosa Batista; Marycel Rosa Felisa Figols de Barboza; Solange Amorim Nogueira; Jairo Wagner; Francisco Romero Cabral; Petrick Marcellus Victorio Mendonça Davoglio; Vanessa Costhek Abílio; Geng Fu; Nan Li; Ling Jian Meng; Ming Chi Shih; Chin-Tu Chen; Edson Amaro Junior; Rodrigo Affonseca Bressan
Journal: Einstein (Sao Paulo) Date: 2012 Apr-Jun

3. Singular value decomposition for photon-processing nuclear imaging systems and applications for reconstruction and computing null functions.

Authors: Abhinav K Jha; Harrison H Barrett; Eric C Frey; Eric Clarkson; Luca Caucci; Matthew A Kupinski
Journal: Phys Med Biol Date: 2015-09-09 Impact factor: 3.609

Review 4. SPECT detectors: the Anger Camera and beyond.

Authors: Todd E Peterson; Lars R Furenlid
Journal: Phys Med Biol Date: 2011-08-09 Impact factor: 3.609

5. Quantitative single-particle digital autoradiography with α-particle emitters for targeted radionuclide therapy using the iQID camera.

Authors: Brian W Miller; Sofia H L Frost; Shani L Frayo; Aimee L Kenoyer; Erlinda Santos; Jon C Jones; Damian J Green; Donald K Hamlin; D Scott Wilbur; Darrell R Fisher; Johnnie J Orozco; Oliver W Press; John M Pagel; Brenda M Sandmaier
Journal: Med Phys Date: 2015-07 Impact factor: 4.071