Literature DB >> 8441043

A stationary hemispherical SPECT imager for three-dimensional brain imaging.

R K Rowe1, J N Aarsvold, H H Barrett, J C Chen, W P Klein, B A Moore, I W Pang, D D Patton, T A White.   

Abstract

A completely stationary, hemispherical-coded aperture SPECT imaging system was designed to produce three-dimensional images of the brain. The system consisted of a hemispherical multiple-pinhole coded aperture and 20 small (100 x 100 mm crystal area) digital gamma cameras. Reconstructions and measured performance specifications from two laboratory versions of the imager are presented. The reconstructed field of view of these systems was an ellipsoidal region with semi-diameters of 100 x 100 x 50 mm. The reconstructed spatial resolution for a point source in air at the center of this field was found to be 4.8 mm FWHM and the corresponding system sensitivity was 36 cps/microCi. An analysis using an ideal-observer model indicated that the multiplexed projection data suffered a 21% degradation relative to similar, but nonmultiplexed SPECT data. Therefore, by this measure, the effective sensitivity of the brain imager was 79% of the measured value.

Mesh:

Year:  1993        PMID: 8441043

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  22 in total

Review 1.  Dynamic single photon emission computed tomography--basic principles and cardiac applications.

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2.  A SPECT imager with synthetic collimation.

Authors:  Ronan J Havelin; Brian W Miller; Harrison H Barrett; Lars R Furenlid; J M Murphy; Mark J Foley
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2013-08-25

Review 3.  Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging.

Authors:  Karen Van Audenhaege; Roel Van Holen; Stefaan Vandenberghe; Christian Vanhove; Scott D Metzler; Stephen C Moore
Journal:  Med Phys       Date:  2015-08       Impact factor: 4.071

Review 4.  The pinhole: gateway to ultra-high-resolution three-dimensional radionuclide imaging.

Authors:  Freek Beekman; Frans van der Have
Journal:  Eur J Nucl Med Mol Imaging       Date:  2007-02       Impact factor: 9.236

Review 5.  Brain single-photon emission CT physics principles.

Authors:  R Accorsi
Journal:  AJNR Am J Neuroradiol       Date:  2008-06-26       Impact factor: 3.825

6.  Imaging assessment of cardioprotection mediated by a dodecafluoropentane oxygen-carrier administered during myocardial infarction.

Authors:  Zhonglin Liu; Christy Barber; Akash Gupta; Li Wan; Young-Wook Won; Lars R Furenlid; Qin Chen; Ankit A Desai; Ming Zhao; David A Bull; Evan C Unger; Diego R Martin
Journal:  Nucl Med Biol       Date:  2019-01-17       Impact factor: 2.408

7.  Performance evaluation of small-animal multipinhole μSPECT scanners for mouse imaging.

Authors:  Steven Deleye; Roel Van Holen; Jeroen Verhaeghe; Stefaan Vandenberghe; Sigrid Stroobants; Steven Staelens
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-01-24       Impact factor: 9.236

8.  Design of a Multi-Pinhole Collimator for I-123 DaTscan Imaging on Dual-Headed SPECT Systems in Combination with a Fan-Beam Collimator.

Authors:  Michael A King; Joyeeta M Mukherjee; Arda Könik; I George Zubal; Joyoni Dey; Robert Licho
Journal:  IEEE Trans Nucl Sci       Date:  2016-02-03       Impact factor: 1.679

9.  Evaluating the protective role of ischaemic preconditioning in rat hearts using a stationary small-animal SPECT imager and 99mTc-glucarate.

Authors:  Zhonglin Liu; Harrison H Barrett; Gail D Stevenson; Lars R Furenlid; Koon Yan Pak; James M Woolfenden
Journal:  Nucl Med Commun       Date:  2008-02       Impact factor: 1.690

10.  Is absolute quantification of dopaminergic neurotransmission studies with 123I SPECT ready for clinical use?

Authors:  Habib Zaidi; Georges El Fakhri
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-07       Impact factor: 9.236

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